Q5JS13: Ras-specific guanine nucleotide-releasing factor RalGPS1

General Information

Protein names	- Ras-specific guanine nucleotide-releasing factor RalGPS1 - Ral GEF with PH domain and SH3-binding motif 1 - Ral guanine nucleotide exchange factor 2 - RalGEF 2 - RalA exchange factor RalGPS1
Gene names	RALGPS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5JS13

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE

Isoforms

- Isoform 2 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 3 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 4 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 5 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 6 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 7 of Ras-specific guanine nucleotide-releasing factor RalGPS1

Sequence View

        10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTREY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSG SARFSRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNMMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLALTSSS AVTNGLSLGS SESSEFSEEM SSGLESPTGP
       430        440        450        460        470        480
CICSLGNSAA VPTMEGPLRR KTLLKEGRKP ALSSWTRYWV ILSGSTLLYY GAKSLRGTDR
       490        500        510        520        530        540
KHYKSTPGKK VSIVGWMVQL PDDPEHPDIF QLNNPDKGNV YKFQTGSRFH AILWHKHLDD
       550
ACKSNRPQVP ANLMSFE

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5JS13-1-unknown	MYKRNG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5JS13-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87447
Q5JS13-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87448
Q5JS13-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87449
Q5JS13-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87450
Q5JS13-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87451
Q5JS13-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87452

TopFIND

Q5JS13: Ras-specific guanine nucleotide-releasing factor RalGPS1

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates