TopFIND 4.0

Q5M7Z0: E3 ubiquitin-protein ligase RNFT1 {ECO:0000305}

General Information

Protein names
- E3 ubiquitin-protein ligase RNFT1 {ECO:0000305}
- 2.3.2.27 {ECO:0000269|PubMed:27485036}
- Protein PTD016
- RING finger and transmembrane domain-containing protein 1
Gene names RNFT1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5M7Z0

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPLFLLSLPT PPSASGHERR QRPEAKTSGS EKKYLRAMQA NRSQLHSPPG TGSSEDASTP 
        70         80         90        100        110        120 
QCVHTRLTGE GSCPHSGDVH IQINSIPKEC AENASSRNIR SGVHSCAHGC VHSRLRGHSH 
       130        140        150        160        170        180 
SEARLTDDTA AESGDHGSSS FSEFRYLFKW LQKSLPYILI LSVKLVMQHI TGISLGIGLL 
       190        200        210        220        230        240 
TTFMYANKSI VNQVFLRERS SKIQCAWLLV FLAGSSVLLY YTFHSQSLYY SLIFLNPTLD 
       250        260        270        280        290        300 
HLSFWEVFWI VGITDFILKF FFMGLKCLIL LVPSFIMPFK SKGYWYMLLE ELCQYYRTFV 
       310        320        330        340        350        360 
PIPVWFRYLI SYGEFGNVTR WSLGILLALL YLILKLLEFF GHLRTFRQVL RIFFTQPSYG 
       370        380        390        400        410        420 
VAASKRQCSD VDDICSICQA EFQKPILLIC QHIFCEECMT LWFNREKTCP LCRTVISDHI 
       430    
NKWKDGATSS HLQIY

Isoforms

- Isoform 2 of RING finger and transmembrane domain-containing protein 1 - Isoform 3 of RING finger and transmembrane domain-containing protein 1 - Isoform 2 of E3 ubiquitin-protein ligase RNFT1 - Isoform 3 of E3 ubiquitin-protein ligase RNFT1

Sequence View

        10         20         30         40         50         60 
MPLFLLSLPT PPSASGHERR QRPEAKTSGS EKKYLRAMQA NRSQLHSPPG TGSSEDASTP 
        70         80         90        100        110        120 
QCVHTRLTGE GSCPHSGDVH IQINSIPKEC AENASSRNIR SGVHSCAHGC VHSRLRGHSH 
       130        140        150        160        170        180 
SEARLTDDTA AESGDHGSSS FSEFRYLFKW LQKSLPYILI LSVKLVMQHI TGISLGIGLL 
       190        200        210        220        230        240 
TTFMYANKSI VNQVFLRERS SKIQCAWLLV FLAGSSVLLY YTFHSQSLYY SLIFLNPTLD 
       250        260        270        280        290        300 
HLSFWEVFWI VGITDFILKF FFMGLKCLIL LVPSFIMPFK SKGYWYMLLE ELCQYYRTFV 
       310        320        330        340        350        360 
PIPVWFRYLI SYGEFGNVTR WSLGILLALL YLILKLLEFF GHLRTFRQVL RIFFTQPSYG 
       370        380        390        400        410        420 
VAASKRQCSD VDDICSICQA EFQKPILLIC QHIFCEECMT LWFNREKTCP LCRTVISDHI 
       430    
NKWKDGATSS HLQIY         10         20         30         40         50         60 
MPLFLLSLPT PPSASGHERR QRPEAKTSGS EKKYLRAMQA NRSQLHSPPG TGSSEDASTP 
        70         80         90        100        110        120 
QCVHTRLTGE GSCPHSGDVH IQINSIPKEC AENASSRNIR SGVHSCAHGC VHSRLRGHSH 
       130        140        150        160        170        180 
SEARLTDDTA AESGDHGSSS FSEFRYLFKW LQKSLPYILI LSVKLVMQHI TGISLGIGLL 
       190        200        210        220        230        240 
TTFMYANKSI VNQVFLRERS SKIQCAWLLV FLAGSSVLLY YTFHSQSLYY SLIFLNPTLD 
       250        260        270        280        290        300 
HLSFWEVFWI VGITDFILKF FFMGLKCLIL LVPSFIMPFK SKGYWYMLLE ELCQYYRTFV 
       310        320        330        340        350        360 
PIPVWFRYLI SYGEFGNVTR WSLGILLALL YLILKLLEFF GHLRTFRQVL RIFFTQPSYG 
       370        380        390        400        410        420 
VAASKRQCSD VDDICSICQA EFQKPILLIC QHIFCEECMT LWFNREKTCP LCRTVISDHI 
       430    
NKWKDGATSS HLQIY         10         20         30         40         50         60 
MPLFLLSLPT PPSASGHERR QRPEAKTSGS EKKYLRAMQA NRSQLHSPPG TGSSEDASTP 
        70         80         90        100        110        120 
QCVHTRLTGE GSCPHSGDVH IQINSIPKEC AENASSRNIR SGVHSCAHGC VHSRLRGHSH 
       130        140        150        160        170        180 
SEARLTDDTA AESGDHGSSS FSEFRYLFKW LQKSLPYILI LSVKLVMQHI TGISLGIGLL 
       190        200        210        220        230        240 
TTFMYANKSI VNQVFLRERS SKIQCAWLLV FLAGSSVLLY YTFHSQSLYY SLIFLNPTLD 
       250        260        270        280        290        300 
HLSFWEVFWI VGITDFILKF FFMGLKCLIL LVPSFIMPFK SKGYWYMLLE ELCQYYRTFV 
       310        320        330        340        350        360 
PIPVWFRYLI SYGEFGNVTR WSLGILLALL YLILKLLEFF GHLRTFRQVL RIFFTQPSYG 
       370        380        390        400        410        420 
VAASKRQCSD VDDICSICQA EFQKPILLIC QHIFCEECMT LWFNREKTCP LCRTVISDHI 
       430    
NKWKDGATSS HLQIY         10         20         30         40         50         60 
MPLFLLSLPT PPSASGHERR QRPEAKTSGS EKKYLRAMQA NRSQLHSPPG TGSSEDASTP 
        70         80         90        100        110        120 
QCVHTRLTGE GSCPHSGDVH IQINSIPKEC AENASSRNIR SGVHSCAHGC VHSRLRGHSH 
       130        140        150        160        170        180 
SEARLTDDTA AESGDHGSSS FSEFRYLFKW LQKSLPYILI LSVKLVMQHI TGISLGIGLL 
       190        200        210        220        230        240 
TTFMYANKSI VNQVFLRERS SKIQCAWLLV FLAGSSVLLY YTFHSQSLYY SLIFLNPTLD 
       250        260        270        280        290        300 
HLSFWEVFWI VGITDFILKF FFMGLKCLIL LVPSFIMPFK SKGYWYMLLE ELCQYYRTFV 
       310        320        330        340        350        360 
PIPVWFRYLI SYGEFGNVTR WSLGILLALL YLILKLLEFF GHLRTFRQVL RIFFTQPSYG 
       370        380        390        400        410        420 
VAASKRQCSD VDDICSICQA EFQKPILLIC QHIFCEECMT LWFNREKTCP LCRTVISDHI 
       430    
NKWKDGATSS HLQIY



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5M7Z0-1-unknown MPLFLL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5M7Z0-1-unknown MPLFLL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88021
    Q5M7Z0-1-unknown MPLFLL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88022

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HLQIY 435 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)