TopFIND 4.0

Q5MY95: Ectonucleoside triphosphate diphosphohydrolase 8

General Information

Protein names
- Ectonucleoside triphosphate diphosphohydrolase 8
- E-NTPDase 8
- NTPDase 8
- NTPDase8
- 3.6.1.5
Gene names ENTPD8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5MY95

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGLSRKEQVF LALLGASGVS GLTALILLLV EATSVLLPTD IKFGIVFDAG SSHTSLFLYQ 
        70         80         90        100        110        120 
WLANKENGTG VVSQALACQV EGPGISSYTS NAAQAGESLQ GCLEEALVLI PEAQHRKTPT 
       130        140        150        160        170        180 
FLGATAGMRL LSRKNSSQAR DIFAAVTQVL GRSPVDFWGA ELLAGQAEGA FGWITVNYGL 
       190        200        210        220        230        240 
GTLVKYSFTG EWIQPPEEML VGALDMGGAS TQITFVPGGP ILDKSTQADF RLYGSDYSVY 
       250        260        270        280        290        300 
THSYLCFGRD QMLSRLLVGL VQSRPAALLR HPCYLSGYQT TLALGPLYES PCVHATPPLS 
       310        320        330        340        350        360 
LPQNLTVEGT GNPGACVSAI RELFNFSSCQ GQEDCAFDGV YQPPLRGQFY AFSNFYYTFH 
       370        380        390        400        410        420 
FLNLTSRQPL STVNATIWEF CQRPWKLVEA SYPGQDRWLR DYCASGLYIL TLLHEGYGFS 
       430        440        450        460        470        480 
EETWPSLEFR KQAGGVDIGW TLGYMLNLTG MIPADAPAQW RAESYGVWVA KVVFMVLALV 
       490    
AVVGAALVQL FWLQD

Isoforms

- Isoform 2 of Ectonucleoside triphosphate diphosphohydrolase 8

Sequence View

        10         20         30         40         50         60 
MGLSRKEQVF LALLGASGVS GLTALILLLV EATSVLLPTD IKFGIVFDAG SSHTSLFLYQ 
        70         80         90        100        110        120 
WLANKENGTG VVSQALACQV EGPGISSYTS NAAQAGESLQ GCLEEALVLI PEAQHRKTPT 
       130        140        150        160        170        180 
FLGATAGMRL LSRKNSSQAR DIFAAVTQVL GRSPVDFWGA ELLAGQAEGA FGWITVNYGL 
       190        200        210        220        230        240 
GTLVKYSFTG EWIQPPEEML VGALDMGGAS TQITFVPGGP ILDKSTQADF RLYGSDYSVY 
       250        260        270        280        290        300 
THSYLCFGRD QMLSRLLVGL VQSRPAALLR HPCYLSGYQT TLALGPLYES PCVHATPPLS 
       310        320        330        340        350        360 
LPQNLTVEGT GNPGACVSAI RELFNFSSCQ GQEDCAFDGV YQPPLRGQFY AFSNFYYTFH 
       370        380        390        400        410        420 
FLNLTSRQPL STVNATIWEF CQRPWKLVEA SYPGQDRWLR DYCASGLYIL TLLHEGYGFS 
       430        440        450        460        470        480 
EETWPSLEFR KQAGGVDIGW TLGYMLNLTG MIPADAPAQW RAESYGVWVA KVVFMVLALV 
       490    
AVVGAALVQL FWLQD



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5MY95-1-unknown MGLSRK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5MY95-1-unknown MGLSRK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73983

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FWLQD 495 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...FWLQD 495 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69601

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)