TopFIND 4.0

Q5PSV9: Mediator of DNA damage checkpoint protein 1

General Information

Protein names
- Mediator of DNA damage checkpoint protein 1
Gene names Mdc1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q5PSV9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MESTQVIDWD AEEEEETELS SGSLGYSVEP IGQLRLFSGT HGPERDFPLY LGKNVVGRSP 
        70         80         90        100        110        120 
DCSVALPFPS ISKQHAVIEI SAWNKAPILQ DCGSLNGTQI VKPPRVLPPG VSHRLRDQEL 
       130        140        150        160        170        180 
ILFADFPCQY HRLDVPPPLV PRSLLTIEKT PRIRIESQNS RVLLAADSEE EGDFPSGRCV 
       190        200        210        220        230        240 
ANGQRNTASP SATVVPESDE EVSSPAPSVP GPSSPFGLGS DTDEEQGQQP GVEESSLADS 
       250        260        270        280        290        300 
SGAAGEAEQP EANGTTAGIQ AQPTEHKLKD TKVKKEAGRA GVSDGSVLER SPTLGEDSDT 
       310        320        330        340        350        360 
EVDEDHKPGF ADSETDVEEE RIPVTPPVAP VKKNQVLLAV GIGDPEAPGV AHLQDCLAGS 
       370        380        390        400        410        420 
GTDVEDKTAL DVPLERNHTP MVINSDTDEE EEEEEEVSAA LTLAHLKERG IGLWSRDPGA 
       430        440        450        460        470        480 
EEVKSQPQVL VEQSQSASGR DSDTDVEEES SGRKREIIPD SPMDVDEALT VTQPESQPPR 
       490        500        510        520        530        540 
RPNDADEYMD MSSPGSHLVV NQASFAVVGK TRAQVEEEVP GPSVILGEKH QVPLEGAQPP 
       550        560        570        580        590        600 
EEAWETAVQE GSSSPEAAAS VRPSQQPVAE DAGTECATAV SEQESTLEVR SQSGSPAAPV 
       610        620        630        640        650        660 
EQVVIHTDTS GDPTLPQREG AQTPTGRERE AHVGRTKSAK ECCDAEPEDL CLPATQCFVE 
       670        680        690        700        710        720 
GESQHPEAVQ SLENEPTQLF PCTLPQEPGP SHLSLQTPGA DTLDVPWEVL ATQPFCLREQ 
       730        740        750        760        770        780 
SETSELHEAH GSQPSLPREP PGHQHLVHTS PVHTELLRIE GREIQTVEKA MGIPKEMADR 
       790        800        810        820        830        840 
MTPEREPLER EIRGRTENSE RDVIGEELIQ GTKDREPKKV LARDSQRKEA DKDLEGNRES 
       850        860        870        880        890        900 
LEVEIEMSKD SQKRERKVEK PEPKREWEPA DLEVTPDRGV TEEGSHDQKG QIASLTLKPG 
       910        920        930        940        950        960 
VGVKDLEGLA SAPIITGSQA DGGKGDPLSP GRQQRGRLSC QTTPAGKASR GDPEPPDHCL 
       970        980        990       1000       1010       1020 
FSSVPEASTQ SLLTSQSQKQ STPQPLFSTS SSEIPLPESL HTKPNVRPRR SSRMTPSPHS 
      1030       1040       1050       1060       1070       1080 
SAALKPNTTC PTNQPAASRP TSRPTRGRAN RSSTRTPELI VPVDPELQPS TSTEQPVIPK 
      1090       1100       1110       1120       1130       1140 
LTSQVTEGRV QMPEPLLTGP EIQSPTSTEQ SVTPDRKPRA TRGRPSKSPN KTPEPLISTG 
      1150       1160       1170       1180       1190       1200 
PELQPPTSIE QPVIPKPTSR VTRGRPRKSS VRTPESVVST GPELQPLTSI EQPVIPEPRA 
      1210       1220       1230       1240       1250       1260 
TRGRPSKSSI KTPESVVPTG PELQPLTSAK QPVTPNLTSR ASRGRSSKSI RTPEPVVQTG 
      1270       1280       1290       1300       1310       1320 
PEFHPSTSTE QPDTREPSSQ ARTRRSAVKT PEASVPTTPE LQPFTSKKQP APKPTALVTQ 
      1330       1340       1350       1360       1370       1380 
GRTYKPSTED CESVGPVAPD FEPSTSTDHL VTPKVTDQSL TLQSSPLSAS PVSSTPDLKP 
      1390       1400       1410       1420       1430       1440 
PVPIAQPVTP EPIPQANHQR KRRAAGKQGS RTVPLGHKSY SALSEPEPQS SASQSSGASE 
      1450       1460       1470       1480       1490       1500 
ADSPRQKRPR RQASQKTVVI KEEPVETEVK EEPQETAIPT PEKRKRDHAE EVTQGKPTRS 
      1510       1520       1530       1540       1550       1560 
RRTKPNQETA PKVLFTGVMD SRGERAVLAL GGSLASSVNE ASHLVTDRIR RTVKFLCALG 
      1570       1580       1590       1600       1610       1620 
KGIPILSLNW LYQSRKAGCF LPPDDYLVTD PEQEKNFSFS LRDSLCRARE RRLLEDYEIH 
      1630       1640       1650       1660       1670       1680 
VTPGVQPPPP QMGEIISCCG GTFLPSMPHS YKLHRVIITC TEDLPRCAIP SRLGLPLLSP 
      1690       1700    
EFLLTGVLKQ EATPEAFVLS NLEMSST

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5PSV9-1-unknown MESTQV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EMSST 1707 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)