TopFIND 4.0

Q5SQS7: SH2 domain-containing protein 4B

General Information

Protein names
- SH2 domain-containing protein 4B
Gene names SH2D4B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5SQS7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLQQILHDMY IDPELLAELS DVQKHILFYK MREEQLRRWK ERETWEALAQ DEGLRPPKTK 
        70         80         90        100        110        120 
RASDKHIQWL LGADGEVWVW IMGEGPGDKP YEEISEELIA ERARLQAQRE AEELWRQKEA 
       130        140        150        160        170        180 
EITKKFRDAL ANEKARILAE KWKVEMEDRK AAKVLEERIH EEFKRKEEEE RKRGEEQIRL 
       190        200        210        220        230        240 
QEEQRAKELY WTLKQAQLHC QASEKEEREW EEQLRRSKAA DEERSRRAQR ARDEYRHHSL 
       250        260        270        280        290        300 
RAIQKGTVAG LSSMFRELGQ SHEQEARLYH HLPDPGLPQP LALPVRTWER PLRPVSRDVI 
       310        320        330        340        350        360 
VRWFKEEQLP RRAGFERNTK FIAPWFHGII SREDAEALLE NMTEGAFLVR VSEKIWGYTL 
       370        380        390        400        410        420 
SYRLQKGFKH FLVDASGDFY SFLGVDPNRH ATLTDLVDFH KEEIITVSGG ELLQEPCGQR 
       430    
DSPPDYHLLF E

Isoforms

- Isoform 2 of SH2 domain-containing protein 4B - Isoform 3 of SH2 domain-containing protein 4B

Sequence View

        10         20         30         40         50         60 
MLQQILHDMY IDPELLAELS DVQKHILFYK MREEQLRRWK ERETWEALAQ DEGLRPPKTK 
        70         80         90        100        110        120 
RASDKHIQWL LGADGEVWVW IMGEGPGDKP YEEISEELIA ERARLQAQRE AEELWRQKEA 
       130        140        150        160        170        180 
EITKKFRDAL ANEKARILAE KWKVEMEDRK AAKVLEERIH EEFKRKEEEE RKRGEEQIRL 
       190        200        210        220        230        240 
QEEQRAKELY WTLKQAQLHC QASEKEEREW EEQLRRSKAA DEERSRRAQR ARDEYRHHSL 
       250        260        270        280        290        300 
RAIQKGTVAG LSSMFRELGQ SHEQEARLYH HLPDPGLPQP LALPVRTWER PLRPVSRDVI 
       310        320        330        340        350        360 
VRWFKEEQLP RRAGFERNTK FIAPWFHGII SREDAEALLE NMTEGAFLVR VSEKIWGYTL 
       370        380        390        400        410        420 
SYRLQKGFKH FLVDASGDFY SFLGVDPNRH ATLTDLVDFH KEEIITVSGG ELLQEPCGQR 
       430    
DSPPDYHLLF E         10         20         30         40         50         60 
MLQQILHDMY IDPELLAELS DVQKHILFYK MREEQLRRWK ERETWEALAQ DEGLRPPKTK 
        70         80         90        100        110        120 
RASDKHIQWL LGADGEVWVW IMGEGPGDKP YEEISEELIA ERARLQAQRE AEELWRQKEA 
       130        140        150        160        170        180 
EITKKFRDAL ANEKARILAE KWKVEMEDRK AAKVLEERIH EEFKRKEEEE RKRGEEQIRL 
       190        200        210        220        230        240 
QEEQRAKELY WTLKQAQLHC QASEKEEREW EEQLRRSKAA DEERSRRAQR ARDEYRHHSL 
       250        260        270        280        290        300 
RAIQKGTVAG LSSMFRELGQ SHEQEARLYH HLPDPGLPQP LALPVRTWER PLRPVSRDVI 
       310        320        330        340        350        360 
VRWFKEEQLP RRAGFERNTK FIAPWFHGII SREDAEALLE NMTEGAFLVR VSEKIWGYTL 
       370        380        390        400        410        420 
SYRLQKGFKH FLVDASGDFY SFLGVDPNRH ATLTDLVDFH KEEIITVSGG ELLQEPCGQR 
       430    
DSPPDYHLLF E



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5SQS7-1-unknown MLQQIL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5SQS7-1-unknown MLQQIL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89498

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HLLFE 431 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)