TopFIND 4.0

Q5SRH9: Tetratricopeptide repeat protein 39A

General Information

Protein names
- Tetratricopeptide repeat protein 39A
- TPR repeat protein 39A
- Differentially expressed in MCF7 with estradiol protein 6
- DEME-6
Gene names TTC39A
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5SRH9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGQKGHKDSL YPCGGTPESS LHEALDQCMT ALDLFLTNQF SEALSYLKPR TKESMYHSLT 
        70         80         90        100        110        120 
YATILEMQAM MTFDPQDILL AGNMMKEAQM LCQRHRRKSS VTDSFSSLVN RPTLGQFTEE 
       130        140        150        160        170        180 
EIHAEVCYAE CLLQRAALTF LQGSSHGGAV RPRALHDPSH ACSCPPGPGR QHLFLLQDEN 
       190        200        210        220        230        240 
MVSFIKGGIK VRNSYQTYKE LDSLVQSSQY CKGENHPHFE GGVKLGVGAF NLTLSMLPTR 
       250        260        270        280        290        300 
ILRLLEFVGF SGNKDYGLLQ LEEGASGHSF RSVLCVMLLL CYHTFLTFVL GTGNVNIEEA 
       310        320        330        340        350        360 
EKLLKPYLNR YPKGAIFLFF AGRIEVIKGN IDAAIRRFEE CCEAQQHWKQ FHHMCYWELM 
       370        380        390        400        410        420 
WCFTYKGQWK MSYFYADLLS KENCWSKATY IYMKAAYLSM FGKEDHKPFG DDEVELFRAV 
       430        440        450        460        470        480 
PGLKLKIAGK SLPTEKFAIR KSRRYFSSNP ISLPVPALEM MYIWNGYAVI GKQPKLTDGI 
       490        500        510        520        530        540 
LEIITKAEEM LEKGPENEYS VDDECLVKLL KGLCLKYLGR VQEAEENFRS ISANEKKIKY 
       550        560        570        580        590        600 
DHYLIPNALL ELALLLMEQD RNEEAIKLLE SAKQNYKNYS MESRTHFRIQ AATLQAKSSL 
       610    
ENSSRSMVSS VSL

Isoforms

- Isoform 2 of Tetratricopeptide repeat protein 39A - Isoform 3 of Tetratricopeptide repeat protein 39A - Isoform 4 of Tetratricopeptide repeat protein 39A - Isoform 5 of Tetratricopeptide repeat protein 39A - Isoform 6 of Tetratricopeptide repeat protein 39A

Sequence View

        10         20         30         40         50         60 
MGQKGHKDSL YPCGGTPESS LHEALDQCMT ALDLFLTNQF SEALSYLKPR TKESMYHSLT 
        70         80         90        100        110        120 
YATILEMQAM MTFDPQDILL AGNMMKEAQM LCQRHRRKSS VTDSFSSLVN RPTLGQFTEE 
       130        140        150        160        170        180 
EIHAEVCYAE CLLQRAALTF LQGSSHGGAV RPRALHDPSH ACSCPPGPGR QHLFLLQDEN 
       190        200        210        220        230        240 
MVSFIKGGIK VRNSYQTYKE LDSLVQSSQY CKGENHPHFE GGVKLGVGAF NLTLSMLPTR 
       250        260        270        280        290        300 
ILRLLEFVGF SGNKDYGLLQ LEEGASGHSF RSVLCVMLLL CYHTFLTFVL GTGNVNIEEA 
       310        320        330        340        350        360 
EKLLKPYLNR YPKGAIFLFF AGRIEVIKGN IDAAIRRFEE CCEAQQHWKQ FHHMCYWELM 
       370        380        390        400        410        420 
WCFTYKGQWK MSYFYADLLS KENCWSKATY IYMKAAYLSM FGKEDHKPFG DDEVELFRAV 
       430        440        450        460        470        480 
PGLKLKIAGK SLPTEKFAIR KSRRYFSSNP ISLPVPALEM MYIWNGYAVI GKQPKLTDGI 
       490        500        510        520        530        540 
LEIITKAEEM LEKGPENEYS VDDECLVKLL KGLCLKYLGR VQEAEENFRS ISANEKKIKY 
       550        560        570        580        590        600 
DHYLIPNALL ELALLLMEQD RNEEAIKLLE SAKQNYKNYS MESRTHFRIQ AATLQAKSSL 
       610    
ENSSRSMVSS VSL         10         20         30         40         50         60 
MGQKGHKDSL YPCGGTPESS LHEALDQCMT ALDLFLTNQF SEALSYLKPR TKESMYHSLT 
        70         80         90        100        110        120 
YATILEMQAM MTFDPQDILL AGNMMKEAQM LCQRHRRKSS VTDSFSSLVN RPTLGQFTEE 
       130        140        150        160        170        180 
EIHAEVCYAE CLLQRAALTF LQGSSHGGAV RPRALHDPSH ACSCPPGPGR QHLFLLQDEN 
       190        200        210        220        230        240 
MVSFIKGGIK VRNSYQTYKE LDSLVQSSQY CKGENHPHFE GGVKLGVGAF NLTLSMLPTR 
       250        260        270        280        290        300 
ILRLLEFVGF SGNKDYGLLQ LEEGASGHSF RSVLCVMLLL CYHTFLTFVL GTGNVNIEEA 
       310        320        330        340        350        360 
EKLLKPYLNR YPKGAIFLFF AGRIEVIKGN IDAAIRRFEE CCEAQQHWKQ FHHMCYWELM 
       370        380        390        400        410        420 
WCFTYKGQWK MSYFYADLLS KENCWSKATY IYMKAAYLSM FGKEDHKPFG DDEVELFRAV 
       430        440        450        460        470        480 
PGLKLKIAGK SLPTEKFAIR KSRRYFSSNP ISLPVPALEM MYIWNGYAVI GKQPKLTDGI 
       490        500        510        520        530        540 
LEIITKAEEM LEKGPENEYS VDDECLVKLL KGLCLKYLGR VQEAEENFRS ISANEKKIKY 
       550        560        570        580        590        600 
DHYLIPNALL ELALLLMEQD RNEEAIKLLE SAKQNYKNYS MESRTHFRIQ AATLQAKSSL 
       610    
ENSSRSMVSS VSL         10         20         30         40         50         60 
MGQKGHKDSL YPCGGTPESS LHEALDQCMT ALDLFLTNQF SEALSYLKPR TKESMYHSLT 
        70         80         90        100        110        120 
YATILEMQAM MTFDPQDILL AGNMMKEAQM LCQRHRRKSS VTDSFSSLVN RPTLGQFTEE 
       130        140        150        160        170        180 
EIHAEVCYAE CLLQRAALTF LQGSSHGGAV RPRALHDPSH ACSCPPGPGR QHLFLLQDEN 
       190        200        210        220        230        240 
MVSFIKGGIK VRNSYQTYKE LDSLVQSSQY CKGENHPHFE GGVKLGVGAF NLTLSMLPTR 
       250        260        270        280        290        300 
ILRLLEFVGF SGNKDYGLLQ LEEGASGHSF RSVLCVMLLL CYHTFLTFVL GTGNVNIEEA 
       310        320        330        340        350        360 
EKLLKPYLNR YPKGAIFLFF AGRIEVIKGN IDAAIRRFEE CCEAQQHWKQ FHHMCYWELM 
       370        380        390        400        410        420 
WCFTYKGQWK MSYFYADLLS KENCWSKATY IYMKAAYLSM FGKEDHKPFG DDEVELFRAV 
       430        440        450        460        470        480 
PGLKLKIAGK SLPTEKFAIR KSRRYFSSNP ISLPVPALEM MYIWNGYAVI GKQPKLTDGI 
       490        500        510        520        530        540 
LEIITKAEEM LEKGPENEYS VDDECLVKLL KGLCLKYLGR VQEAEENFRS ISANEKKIKY 
       550        560        570        580        590        600 
DHYLIPNALL ELALLLMEQD RNEEAIKLLE SAKQNYKNYS MESRTHFRIQ AATLQAKSSL 
       610    
ENSSRSMVSS VSL         10         20         30         40         50         60 
MGQKGHKDSL YPCGGTPESS LHEALDQCMT ALDLFLTNQF SEALSYLKPR TKESMYHSLT 
        70         80         90        100        110        120 
YATILEMQAM MTFDPQDILL AGNMMKEAQM LCQRHRRKSS VTDSFSSLVN RPTLGQFTEE 
       130        140        150        160        170        180 
EIHAEVCYAE CLLQRAALTF LQGSSHGGAV RPRALHDPSH ACSCPPGPGR QHLFLLQDEN 
       190        200        210        220        230        240 
MVSFIKGGIK VRNSYQTYKE LDSLVQSSQY CKGENHPHFE GGVKLGVGAF NLTLSMLPTR 
       250        260        270        280        290        300 
ILRLLEFVGF SGNKDYGLLQ LEEGASGHSF RSVLCVMLLL CYHTFLTFVL GTGNVNIEEA 
       310        320        330        340        350        360 
EKLLKPYLNR YPKGAIFLFF AGRIEVIKGN IDAAIRRFEE CCEAQQHWKQ FHHMCYWELM 
       370        380        390        400        410        420 
WCFTYKGQWK MSYFYADLLS KENCWSKATY IYMKAAYLSM FGKEDHKPFG DDEVELFRAV 
       430        440        450        460        470        480 
PGLKLKIAGK SLPTEKFAIR KSRRYFSSNP ISLPVPALEM MYIWNGYAVI GKQPKLTDGI 
       490        500        510        520        530        540 
LEIITKAEEM LEKGPENEYS VDDECLVKLL KGLCLKYLGR VQEAEENFRS ISANEKKIKY 
       550        560        570        580        590        600 
DHYLIPNALL ELALLLMEQD RNEEAIKLLE SAKQNYKNYS MESRTHFRIQ AATLQAKSSL 
       610    
ENSSRSMVSS VSL         10         20         30         40         50         60 
MGQKGHKDSL YPCGGTPESS LHEALDQCMT ALDLFLTNQF SEALSYLKPR TKESMYHSLT 
        70         80         90        100        110        120 
YATILEMQAM MTFDPQDILL AGNMMKEAQM LCQRHRRKSS VTDSFSSLVN RPTLGQFTEE 
       130        140        150        160        170        180 
EIHAEVCYAE CLLQRAALTF LQGSSHGGAV RPRALHDPSH ACSCPPGPGR QHLFLLQDEN 
       190        200        210        220        230        240 
MVSFIKGGIK VRNSYQTYKE LDSLVQSSQY CKGENHPHFE GGVKLGVGAF NLTLSMLPTR 
       250        260        270        280        290        300 
ILRLLEFVGF SGNKDYGLLQ LEEGASGHSF RSVLCVMLLL CYHTFLTFVL GTGNVNIEEA 
       310        320        330        340        350        360 
EKLLKPYLNR YPKGAIFLFF AGRIEVIKGN IDAAIRRFEE CCEAQQHWKQ FHHMCYWELM 
       370        380        390        400        410        420 
WCFTYKGQWK MSYFYADLLS KENCWSKATY IYMKAAYLSM FGKEDHKPFG DDEVELFRAV 
       430        440        450        460        470        480 
PGLKLKIAGK SLPTEKFAIR KSRRYFSSNP ISLPVPALEM MYIWNGYAVI GKQPKLTDGI 
       490        500        510        520        530        540 
LEIITKAEEM LEKGPENEYS VDDECLVKLL KGLCLKYLGR VQEAEENFRS ISANEKKIKY 
       550        560        570        580        590        600 
DHYLIPNALL ELALLLMEQD RNEEAIKLLE SAKQNYKNYS MESRTHFRIQ AATLQAKSSL 
       610    
ENSSRSMVSS VSL



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5SRH9-1-unknown MGQKGH... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5SRH9-393-unknown MKAAYL... 393 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93319
    Q5SRH9-393-unknown MKAAYL... 393 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt103574
    Q5SRH9-393-unknown MKAAYL... 393 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt103575

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)