Q5SYB0: FERM and PDZ domain-containing protein 1
| Protein names | - FERM and PDZ domain-containing protein 1 - FERM domain-containing protein 2 |
|---|---|
| Gene names | FRMPD1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q5SYB0 |
2
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEELETSLFQ TRKAHRIEQM VARWLRRSRD SSARAKVAAA DGPARNPTQT LIPVRHTVKI
70 80 90 100 110 120
DKDTLLQDYG FHISESLPLT VVAVTAGGSA HGKLFPGDQI LQMNNEPAED LSWERAVDIL
130 140 150 160 170 180
REAEDSLSIT VVRCTSGVPK SSFLTEEKRA RLKTNPVKVH FAEEVLISGH SQGNSLLCMP
190 200 210 220 230 240
NVLKLYLENG QTKAFKFEAN TTVKDIILTV KEKLSIRSIE YFALALEEQY SISRLHLLHE
250 260 270 280 290 300
EELIQQVVER EESHDYRCLF RVCFVPKDPL DLLKEDPVAF EYLYLQSCSD VLQERFAVEM
310 320 330 340 350 360
KCSSALRLAA LHIQERIYAC AQPQKISLKY IEKDWGIENF ISPTLLRNMK GKDIKKAISF
370 380 390 400 410 420
HMKRNQNLLE PRQKQLISAA QLRLNYLQIL GELKTYGGRI FNATLMLQDR ESYIALLVGA
430 440 450 460 470 480
KYGISQVINS KLNIMSTLAE FANISRVELT EESEKVSVVK VYLQDVKVLT LLLESNSAKD
490 500 510 520 530 540
LACLIAGYYR LLVDPVTSIF LWPGNKQQAH RVSAEEGYES RACSDSEESS EVDCVLEPLS
550 560 570 580 590 600
DRRLVKLAPC RSLIKEEQPP GNSPTPEVAR RGPSTCGASS TTDSAESEAS DSANTESRGY
610 620 630 640 650 660
RTSGSSESMD ALEEDDLDTC SSSRSTFFHF GSPGLAESID SDSQEERSGI ETSGFLCLLD
670 680 690 700 710 720
LAQRANPQCQ KTEFSESAAL ETFGWAPELS TVRLDPRLYE GSHADYYSLC SSVSPASYLS
730 740 750 760 770 780
DSSESTASRQ GGAPPAWGQQ GWTEAQPSSM LEPLALHPPL AFEDGSSDEE YYDAADKLTP
790 800 810 820 830 840
PGPPSGPRDV STAEPSATSL QNKASTSSPE NSLPCGPDGR QPSRRGGVKK YAKTLRKRRS
850 860 870 880 890 900
FLQTDYTSQV SFPLVPSASL ESVDDVCYYD REPYLALGAP SPTVSSLQDM QGEPGLLETK
910 920 930 940 950 960
ALGLLAPLRE TKSTNPASRV MEMEPETMET KSVIDSRVSS ISAIRFRIDP NNKENSGVVP
970 980 990 1000 1010 1020
AASSSASTPH CSNPGSSGPD TAQARPSQIL PLSQDLDGIA PKEPTIEHGD SSFSLSSGDP
1030 1040 1050 1060 1070 1080
NPDRACLASN PGLNNVSQGD TLELQLEPHV QLEMGLESFC TNHIQETAPK YTEPLLSPRD
1090 1100 1110 1120 1130 1140
EPRSDECGIN PGEKIASIPT KEEPQGQLSL ERDREVTNKN GTNVFQEESR KDSGDSPGDV
1150 1160 1170 1180 1190 1200
SNNVSQTLDI SSPAGKIVTS LSLDAPVTGT EQIPPHPPRD PQGQSREPPG QGCQAQEQKL
1210 1220 1230 1240 1250 1260
FVELDLDPDF FLGKQTVSPA VPPEGIKAEA PNHVTGQDIA PRDSPEWVCF NPEPSLPEPL
1270 1280 1290 1300 1310 1320
PCPQEDPHLE TSNHCLLSEG KSDSSSICLS AEKSFLCFAP ESHPEVSASL RVATSLGFAG
1330 1340 1350 1360 1370 1380
MNEMVAPRIG MDQCSCQFSY ATCFRGPQPE TEEEDRDLEA HPMAPLTSPP SAGSPVVLPW
1390 1400 1410 1420 1430 1440
RPARAHSCTT APLSRKSHIW PEYCSRALRQ LKATPASTPE GFIQLMESLL ELQDILETSW
1450 1460 1470 1480 1490 1500
GVGNKHPPEK CTWHFTESRS RLCMGSQKLL SSCRHVIRMD QSPEEMQGAV RDTFQHLVQL
1510 1520 1530 1540 1550 1560
AGLCFQFTDC SRCSARHREA AGNLRDVVYT YHQFIEAAKS TCERGYHDLS VKLLARQCTA
1570
LTAAVFCLTQ KFRASTAL
Isoforms
- Isoform 2 of FERM and PDZ domain-containing protein 1 - Isoform 3 of FERM and PDZ domain-containing protein 1Sequence View
10 20 30 40 50 60
MEELETSLFQ TRKAHRIEQM VARWLRRSRD SSARAKVAAA DGPARNPTQT LIPVRHTVKI
70 80 90 100 110 120
DKDTLLQDYG FHISESLPLT VVAVTAGGSA HGKLFPGDQI LQMNNEPAED LSWERAVDIL
130 140 150 160 170 180
REAEDSLSIT VVRCTSGVPK SSFLTEEKRA RLKTNPVKVH FAEEVLISGH SQGNSLLCMP
190 200 210 220 230 240
NVLKLYLENG QTKAFKFEAN TTVKDIILTV KEKLSIRSIE YFALALEEQY SISRLHLLHE
250 260 270 280 290 300
EELIQQVVER EESHDYRCLF RVCFVPKDPL DLLKEDPVAF EYLYLQSCSD VLQERFAVEM
310 320 330 340 350 360
KCSSALRLAA LHIQERIYAC AQPQKISLKY IEKDWGIENF ISPTLLRNMK GKDIKKAISF
370 380 390 400 410 420
HMKRNQNLLE PRQKQLISAA QLRLNYLQIL GELKTYGGRI FNATLMLQDR ESYIALLVGA
430 440 450 460 470 480
KYGISQVINS KLNIMSTLAE FANISRVELT EESEKVSVVK VYLQDVKVLT LLLESNSAKD
490 500 510 520 530 540
LACLIAGYYR LLVDPVTSIF LWPGNKQQAH RVSAEEGYES RACSDSEESS EVDCVLEPLS
550 560 570 580 590 600
DRRLVKLAPC RSLIKEEQPP GNSPTPEVAR RGPSTCGASS TTDSAESEAS DSANTESRGY
610 620 630 640 650 660
RTSGSSESMD ALEEDDLDTC SSSRSTFFHF GSPGLAESID SDSQEERSGI ETSGFLCLLD
670 680 690 700 710 720
LAQRANPQCQ KTEFSESAAL ETFGWAPELS TVRLDPRLYE GSHADYYSLC SSVSPASYLS
730 740 750 760 770 780
DSSESTASRQ GGAPPAWGQQ GWTEAQPSSM LEPLALHPPL AFEDGSSDEE YYDAADKLTP
790 800 810 820 830 840
PGPPSGPRDV STAEPSATSL QNKASTSSPE NSLPCGPDGR QPSRRGGVKK YAKTLRKRRS
850 860 870 880 890 900
FLQTDYTSQV SFPLVPSASL ESVDDVCYYD REPYLALGAP SPTVSSLQDM QGEPGLLETK
910 920 930 940 950 960
ALGLLAPLRE TKSTNPASRV MEMEPETMET KSVIDSRVSS ISAIRFRIDP NNKENSGVVP
970 980 990 1000 1010 1020
AASSSASTPH CSNPGSSGPD TAQARPSQIL PLSQDLDGIA PKEPTIEHGD SSFSLSSGDP
1030 1040 1050 1060 1070 1080
NPDRACLASN PGLNNVSQGD TLELQLEPHV QLEMGLESFC TNHIQETAPK YTEPLLSPRD
1090 1100 1110 1120 1130 1140
EPRSDECGIN PGEKIASIPT KEEPQGQLSL ERDREVTNKN GTNVFQEESR KDSGDSPGDV
1150 1160 1170 1180 1190 1200
SNNVSQTLDI SSPAGKIVTS LSLDAPVTGT EQIPPHPPRD PQGQSREPPG QGCQAQEQKL
1210 1220 1230 1240 1250 1260
FVELDLDPDF FLGKQTVSPA VPPEGIKAEA PNHVTGQDIA PRDSPEWVCF NPEPSLPEPL
1270 1280 1290 1300 1310 1320
PCPQEDPHLE TSNHCLLSEG KSDSSSICLS AEKSFLCFAP ESHPEVSASL RVATSLGFAG
1330 1340 1350 1360 1370 1380
MNEMVAPRIG MDQCSCQFSY ATCFRGPQPE TEEEDRDLEA HPMAPLTSPP SAGSPVVLPW
1390 1400 1410 1420 1430 1440
RPARAHSCTT APLSRKSHIW PEYCSRALRQ LKATPASTPE GFIQLMESLL ELQDILETSW
1450 1460 1470 1480 1490 1500
GVGNKHPPEK CTWHFTESRS RLCMGSQKLL SSCRHVIRMD QSPEEMQGAV RDTFQHLVQL
1510 1520 1530 1540 1550 1560
AGLCFQFTDC SRCSARHREA AGNLRDVVYT YHQFIEAAKS TCERGYHDLS VKLLARQCTA
1570
LTAAVFCLTQ KFRASTAL
10 20 30 40 50 60
MEELETSLFQ TRKAHRIEQM VARWLRRSRD SSARAKVAAA DGPARNPTQT LIPVRHTVKI
70 80 90 100 110 120
DKDTLLQDYG FHISESLPLT VVAVTAGGSA HGKLFPGDQI LQMNNEPAED LSWERAVDIL
130 140 150 160 170 180
REAEDSLSIT VVRCTSGVPK SSFLTEEKRA RLKTNPVKVH FAEEVLISGH SQGNSLLCMP
190 200 210 220 230 240
NVLKLYLENG QTKAFKFEAN TTVKDIILTV KEKLSIRSIE YFALALEEQY SISRLHLLHE
250 260 270 280 290 300
EELIQQVVER EESHDYRCLF RVCFVPKDPL DLLKEDPVAF EYLYLQSCSD VLQERFAVEM
310 320 330 340 350 360
KCSSALRLAA LHIQERIYAC AQPQKISLKY IEKDWGIENF ISPTLLRNMK GKDIKKAISF
370 380 390 400 410 420
HMKRNQNLLE PRQKQLISAA QLRLNYLQIL GELKTYGGRI FNATLMLQDR ESYIALLVGA
430 440 450 460 470 480
KYGISQVINS KLNIMSTLAE FANISRVELT EESEKVSVVK VYLQDVKVLT LLLESNSAKD
490 500 510 520 530 540
LACLIAGYYR LLVDPVTSIF LWPGNKQQAH RVSAEEGYES RACSDSEESS EVDCVLEPLS
550 560 570 580 590 600
DRRLVKLAPC RSLIKEEQPP GNSPTPEVAR RGPSTCGASS TTDSAESEAS DSANTESRGY
610 620 630 640 650 660
RTSGSSESMD ALEEDDLDTC SSSRSTFFHF GSPGLAESID SDSQEERSGI ETSGFLCLLD
670 680 690 700 710 720
LAQRANPQCQ KTEFSESAAL ETFGWAPELS TVRLDPRLYE GSHADYYSLC SSVSPASYLS
730 740 750 760 770 780
DSSESTASRQ GGAPPAWGQQ GWTEAQPSSM LEPLALHPPL AFEDGSSDEE YYDAADKLTP
790 800 810 820 830 840
PGPPSGPRDV STAEPSATSL QNKASTSSPE NSLPCGPDGR QPSRRGGVKK YAKTLRKRRS
850 860 870 880 890 900
FLQTDYTSQV SFPLVPSASL ESVDDVCYYD REPYLALGAP SPTVSSLQDM QGEPGLLETK
910 920 930 940 950 960
ALGLLAPLRE TKSTNPASRV MEMEPETMET KSVIDSRVSS ISAIRFRIDP NNKENSGVVP
970 980 990 1000 1010 1020
AASSSASTPH CSNPGSSGPD TAQARPSQIL PLSQDLDGIA PKEPTIEHGD SSFSLSSGDP
1030 1040 1050 1060 1070 1080
NPDRACLASN PGLNNVSQGD TLELQLEPHV QLEMGLESFC TNHIQETAPK YTEPLLSPRD
1090 1100 1110 1120 1130 1140
EPRSDECGIN PGEKIASIPT KEEPQGQLSL ERDREVTNKN GTNVFQEESR KDSGDSPGDV
1150 1160 1170 1180 1190 1200
SNNVSQTLDI SSPAGKIVTS LSLDAPVTGT EQIPPHPPRD PQGQSREPPG QGCQAQEQKL
1210 1220 1230 1240 1250 1260
FVELDLDPDF FLGKQTVSPA VPPEGIKAEA PNHVTGQDIA PRDSPEWVCF NPEPSLPEPL
1270 1280 1290 1300 1310 1320
PCPQEDPHLE TSNHCLLSEG KSDSSSICLS AEKSFLCFAP ESHPEVSASL RVATSLGFAG
1330 1340 1350 1360 1370 1380
MNEMVAPRIG MDQCSCQFSY ATCFRGPQPE TEEEDRDLEA HPMAPLTSPP SAGSPVVLPW
1390 1400 1410 1420 1430 1440
RPARAHSCTT APLSRKSHIW PEYCSRALRQ LKATPASTPE GFIQLMESLL ELQDILETSW
1450 1460 1470 1480 1490 1500
GVGNKHPPEK CTWHFTESRS RLCMGSQKLL SSCRHVIRMD QSPEEMQGAV RDTFQHLVQL
1510 1520 1530 1540 1550 1560
AGLCFQFTDC SRCSARHREA AGNLRDVVYT YHQFIEAAKS TCERGYHDLS VKLLARQCTA
1570
LTAAVFCLTQ KFRASTAL
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q5SYB0-1-unknown | MEELET... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q5SYB0-179-unknown | MPNVLK... | 179 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000437762 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...VKIDKD | 62 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000439868 | |||
| ...ASTAL | 1578 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|