TopFIND 4.0

Q5T9S5: Coiled-coil domain-containing protein 18

General Information

Protein names
- Coiled-coil domain-containing protein 18
- Sarcoma antigen NY-SAR-24
Gene names CCDC18
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5T9S5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MESSSSDYYN KDNEEESLLA NVASLRHELK ITEWSLQSLG EELSSVSPSE NSDYAPNPSR 
        70         80         90        100        110        120 
SEKLILDVQP SHPGLLNYSP YENVCKISGS STDFQKKPRD KMFSSSAPVD QEIKSLREKL 
       130        140        150        160        170        180 
NKLRQQNACL VTQNHSLMTK FESIHFELTQ SRAKVSMLES AQQQAASVPI LEEQIINLEA 
       190        200        210        220        230        240 
EVSAQDKVLR EAENKLEQSQ KMVIEKEQSL QESKEECIKL KVDLLEQTKQ GKRAERQRNE 
       250        260        270        280        290        300 
ALYNAEELSK AFQQYKKKVA EKLEKVQAEE EILERNLTNC EKENKRLQER CGLYKSELEI 
       310        320        330        340        350        360 
LKEKLRQLKE ENNNGKEKLR IMAVKNSEVM AQLTESRQSI LKLESELENK DEILRDKFSL 
       370        380        390        400        410        420 
MNENRELKVR VAAQNERLDL CQQEIESSRV ELRSLEKIIS QLPLKRELFG FKSYLSKYQM 
       430        440        450        460        470        480 
SSFSNKEDRC IGCCEANKLV ISELRIKLAI KEAEIQKLHA NLTANQLSQS LITCNDSQES 
       490        500        510        520        530        540 
SKLSSLETEP VKLGGHQVES VKDQNQHTMN KQYEKERQRL VTGIEELRTK LIQIEAENSD 
       550        560        570        580        590        600 
LKVNMAHRTS QFQLIQEELL EKASNSSKLE SEMTKKCSQL LTLEKQLEEK IVAYSSIAAK 
       610        620        630        640        650        660 
NAELEQELME KNEKIRSLET NINTEHEKIC LAFEKAKKIH LEQHKEMEKQ IERLEAQLEK 
       670        680        690        700        710        720 
KDQQFKEQEK TMSMLQQDII CKQHHLESLD RLLTESKGEM KKENMKKDEA LKALQNQVSE 
       730        740        750        760        770        780 
ETIKVRQLDS ALEICKEELV LHLNQLEGNK EKFEKQLKKK SEEVYCLQKE LKIKNHSLQE 
       790        800        810        820        830        840 
TSEQNVILQH TLQQQQQMLQ QETIRNGELE DTQTKLEKQV SKLEQELQKQ RESSAEKLRK 
       850        860        870        880        890        900 
MEEKCESAAH EADLKRQKVI ELTGTARQVK IEMDQYKEEL SKMEKEIMHL KRDGENKAMH 
       910        920        930        940        950        960 
LSQLDMILDQ TKTELEKKTN AVKELEKLQH STETELTEAL QKREVLETEL QNAHGELKST 
       970        980        990       1000       1010       1020 
LRQLQELRDV LQKAQLSLEE KYTTIKDLTA ELRECKMEIE DKKQELLEMD QALKERNWEL 
      1030       1040       1050       1060       1070       1080 
KQRAAQVTHL DMTIREHRGE MEQKIIKLEG TLEKSELELK ECNKQIESLN DKLQNAKEQL 
      1090       1100       1110       1120       1130       1140 
REKEFIMLQN EQEISQLKKE IERTQQRMKE MESVMKEQEQ YIATQYKEAI DLGQELRLTR 
      1150       1160       1170       1180       1190       1200 
EQVQNSHTEL AEARHQQVQA QREIERLSSE LEDMKQLSKE KDAHGNHLAE ELGASKVREA 
      1210       1220       1230       1240       1250       1260 
HLEARMQAEI KKLSAEVESL KEAYHMEMIS HQENHAKWKI SADSQKSSVQ QLNEQLEKAK 
      1270       1280       1290       1300       1310       1320 
LELEEAQDTV SNLHQQVQDR NEVIEAANEA LLTKESELTR LQAKISGHEK AEDIKFLPAP 
      1330       1340       1350       1360       1370       1380 
FTSPTEIMPD VQDPKFAKCF HTSFSKCTKL RRSISASDLT FKIHGDEDLS EELLQDLKKM 
      1390       1400       1410       1420       1430       1440 
QLEQPSTLEE SHKNLTYTQP DSFKPLTYNL EADSSENNDF NTLSGMLRYI NKEVRLLKKS 
      1450    
SMQTGAGLNQ GENV

Isoforms

- Isoform 2 of Coiled-coil domain-containing protein 18

Sequence View

        10         20         30         40         50         60 
MESSSSDYYN KDNEEESLLA NVASLRHELK ITEWSLQSLG EELSSVSPSE NSDYAPNPSR 
        70         80         90        100        110        120 
SEKLILDVQP SHPGLLNYSP YENVCKISGS STDFQKKPRD KMFSSSAPVD QEIKSLREKL 
       130        140        150        160        170        180 
NKLRQQNACL VTQNHSLMTK FESIHFELTQ SRAKVSMLES AQQQAASVPI LEEQIINLEA 
       190        200        210        220        230        240 
EVSAQDKVLR EAENKLEQSQ KMVIEKEQSL QESKEECIKL KVDLLEQTKQ GKRAERQRNE 
       250        260        270        280        290        300 
ALYNAEELSK AFQQYKKKVA EKLEKVQAEE EILERNLTNC EKENKRLQER CGLYKSELEI 
       310        320        330        340        350        360 
LKEKLRQLKE ENNNGKEKLR IMAVKNSEVM AQLTESRQSI LKLESELENK DEILRDKFSL 
       370        380        390        400        410        420 
MNENRELKVR VAAQNERLDL CQQEIESSRV ELRSLEKIIS QLPLKRELFG FKSYLSKYQM 
       430        440        450        460        470        480 
SSFSNKEDRC IGCCEANKLV ISELRIKLAI KEAEIQKLHA NLTANQLSQS LITCNDSQES 
       490        500        510        520        530        540 
SKLSSLETEP VKLGGHQVES VKDQNQHTMN KQYEKERQRL VTGIEELRTK LIQIEAENSD 
       550        560        570        580        590        600 
LKVNMAHRTS QFQLIQEELL EKASNSSKLE SEMTKKCSQL LTLEKQLEEK IVAYSSIAAK 
       610        620        630        640        650        660 
NAELEQELME KNEKIRSLET NINTEHEKIC LAFEKAKKIH LEQHKEMEKQ IERLEAQLEK 
       670        680        690        700        710        720 
KDQQFKEQEK TMSMLQQDII CKQHHLESLD RLLTESKGEM KKENMKKDEA LKALQNQVSE 
       730        740        750        760        770        780 
ETIKVRQLDS ALEICKEELV LHLNQLEGNK EKFEKQLKKK SEEVYCLQKE LKIKNHSLQE 
       790        800        810        820        830        840 
TSEQNVILQH TLQQQQQMLQ QETIRNGELE DTQTKLEKQV SKLEQELQKQ RESSAEKLRK 
       850        860        870        880        890        900 
MEEKCESAAH EADLKRQKVI ELTGTARQVK IEMDQYKEEL SKMEKEIMHL KRDGENKAMH 
       910        920        930        940        950        960 
LSQLDMILDQ TKTELEKKTN AVKELEKLQH STETELTEAL QKREVLETEL QNAHGELKST 
       970        980        990       1000       1010       1020 
LRQLQELRDV LQKAQLSLEE KYTTIKDLTA ELRECKMEIE DKKQELLEMD QALKERNWEL 
      1030       1040       1050       1060       1070       1080 
KQRAAQVTHL DMTIREHRGE MEQKIIKLEG TLEKSELELK ECNKQIESLN DKLQNAKEQL 
      1090       1100       1110       1120       1130       1140 
REKEFIMLQN EQEISQLKKE IERTQQRMKE MESVMKEQEQ YIATQYKEAI DLGQELRLTR 
      1150       1160       1170       1180       1190       1200 
EQVQNSHTEL AEARHQQVQA QREIERLSSE LEDMKQLSKE KDAHGNHLAE ELGASKVREA 
      1210       1220       1230       1240       1250       1260 
HLEARMQAEI KKLSAEVESL KEAYHMEMIS HQENHAKWKI SADSQKSSVQ QLNEQLEKAK 
      1270       1280       1290       1300       1310       1320 
LELEEAQDTV SNLHQQVQDR NEVIEAANEA LLTKESELTR LQAKISGHEK AEDIKFLPAP 
      1330       1340       1350       1360       1370       1380 
FTSPTEIMPD VQDPKFAKCF HTSFSKCTKL RRSISASDLT FKIHGDEDLS EELLQDLKKM 
      1390       1400       1410       1420       1430       1440 
QLEQPSTLEE SHKNLTYTQP DSFKPLTYNL EADSSENNDF NTLSGMLRYI NKEVRLLKKS 
      1450    
SMQTGAGLNQ GENV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5T9S5-1-unknown MESSSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5T9S5-1-unknown MESSSS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69659

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QGENV 1454 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)