TopFIND 4.0

Q5U349: Ubiquitin carboxyl-terminal hydrolase 2

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase 2
- 3.4.19.12
- 41 kDa ubiquitin-specific protease
- Deubiquitinating enzyme 2
- Ubiquitin thioesterase 2
- Ubiquitin-specific-processing protease 2
- Ubiquitin-specific-processing protease testis
- UBP-t
Gene names Usp2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q5U349

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQLSSTLKR YTESSRYTDA PYAKSGYGTY TPSSYGANLA ASFLEKEKLG FKPVSPTSFL 
        70         80         90        100        110        120 
PRPRTYGPSS ILDCDRGRPL LRSDITGGSK RSESQTRGNE RPSGSGLNGG SGFPYGVTSN 
       130        140        150        160        170        180 
SLSYLPMNAR DQGVTLGQKK SNSQSDLARD FSSLRTSDSY RTSDGYRASD GFRIDPGNLG 
       190        200        210        220        230        240 
RSPMLARTRK ELCALQGLYQ AASRSEYLTD YLENYGRKGS APQVLTQAPP SRVPEVLSPT 
       250        260        270        280        290        300 
YRPSGRYTLW EKNKGQASGP SRSTSPGRDT MNSKSAQGLA GLRNLGNTCF MNSILQCLSN 
       310        320        330        340        350        360 
TRELRDYCLQ RLYMRDLGHT SSAHTALMEE FAKLIQTIWT SSPNDVVSPS EFKTQIQRYA 
       370        380        390        400        410        420 
PRFVGYNQQD AQEFLRFLLD GLHNEVNRVA ARPKPSPESL DHLPDEEKGR QMWRKYLERE 
       430        440        450        460        470        480 
DSRIGDLFVG QLKSSLTCTD CGYCSTVFDP FWDLSLPIAK RGYPEVTLMD CMRLFTKEDV 
       490        500        510        520        530        540 
LDGDEKPTCC RCRARKRCIK KFSVQRFPKI LVLHLKRFSE SRIRTSKLTT FVNFPLRDLD 
       550        560        570        580        590        600 
LREFASENTN HAVYNLYAVS NHSGTTMGGH YTAYCRSPVT GEWHTFNDSS VTPMSSSQVR 
       610    
TSDAYLLFYE LASPPSRM

Isoforms

- Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 2

Sequence View

        10         20         30         40         50         60 
MSQLSSTLKR YTESSRYTDA PYAKSGYGTY TPSSYGANLA ASFLEKEKLG FKPVSPTSFL 
        70         80         90        100        110        120 
PRPRTYGPSS ILDCDRGRPL LRSDITGGSK RSESQTRGNE RPSGSGLNGG SGFPYGVTSN 
       130        140        150        160        170        180 
SLSYLPMNAR DQGVTLGQKK SNSQSDLARD FSSLRTSDSY RTSDGYRASD GFRIDPGNLG 
       190        200        210        220        230        240 
RSPMLARTRK ELCALQGLYQ AASRSEYLTD YLENYGRKGS APQVLTQAPP SRVPEVLSPT 
       250        260        270        280        290        300 
YRPSGRYTLW EKNKGQASGP SRSTSPGRDT MNSKSAQGLA GLRNLGNTCF MNSILQCLSN 
       310        320        330        340        350        360 
TRELRDYCLQ RLYMRDLGHT SSAHTALMEE FAKLIQTIWT SSPNDVVSPS EFKTQIQRYA 
       370        380        390        400        410        420 
PRFVGYNQQD AQEFLRFLLD GLHNEVNRVA ARPKPSPESL DHLPDEEKGR QMWRKYLERE 
       430        440        450        460        470        480 
DSRIGDLFVG QLKSSLTCTD CGYCSTVFDP FWDLSLPIAK RGYPEVTLMD CMRLFTKEDV 
       490        500        510        520        530        540 
LDGDEKPTCC RCRARKRCIK KFSVQRFPKI LVLHLKRFSE SRIRTSKLTT FVNFPLRDLD 
       550        560        570        580        590        600 
LREFASENTN HAVYNLYAVS NHSGTTMGGH YTAYCRSPVT GEWHTFNDSS VTPMSSSQVR 
       610    
TSDAYLLFYE LASPPSRM



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5U349-1-unknown MSQLSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PPSRM 618 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PPSRM 618 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153622

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)