Q5VVW2: GTPase-activating Rap/Ran-GAP domain-like protein 3

General Information

Protein names	- GTPase-activating Rap/Ran-GAP domain-like protein 3
Gene names	GARNL3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5VVW2

2 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of GTPase-activating Rap/Ran-GAP domain-like protein 3 - Isoform 3 of GTPase-activating Rap/Ran-GAP domain-like protein 3 - Isoform 4 of GTPase-activating Rap/Ran-GAP domain-like protein 3 - Isoform 5 of GTPase-activating Rap/Ran-GAP domain-like protein 3

Sequence View

        10         20         30         40         50         60
MVVDFCRRFV ARSLCIILMK HFCSSSVSED LGCRRGDFSR KHYGSVELLI SSDADGAIQR
        70         80         90        100        110        120
AGRFRVENGS SDENATALPG TWRRTDVHLE NPEYHTRWYF KYFLGQVHQN YIGNDAEKSP
       130        140        150        160        170        180
FFLSVTLSDQ NNQRVPQYRA ILWRKTGTQK ICLPYSPTKT LSVKSILSAM NLDKFEKGPR
       190        200        210        220        230        240
EIFHPEIQKD LLVLEEQEGS VNFKFGVLFA KDGQLTDDEM FSNEIGSEPF QKFLNLLGDT
       250        260        270        280        290        300
ITLKGWTGYR GGLDTKNDTT GIHSVYTVYQ GHEIMFHVST MLPYSKENKQ QVERKRHIGN
       310        320        330        340        350        360
DIVTIVFQEG EESSPAFKPS MIRSHFTHIF ALVRYNQQND NYRLKIFSEE SVPLFGPPLP
       370        380        390        400        410        420
TPPVFTDHQE FRDFLLVKLI NGEKATLETP TFAQKRRRTL DMLIRSLHQD LMPDLHKNML
       430        440        450        460        470        480
NRRSFSDVLP ESPKSARKKE EARQAEFVRI GQALKLKSIV RGDAPSSLAA SGICKKEPWE
       490        500        510        520        530        540
PQCFCSNFPH EAVCADPWGQ ALLVSTDAGV LLVDDDLPSV PVFDRTLPVK QMHVLETLDL
       550        560        570        580        590        600
LVLRADKGKD ARLFVFRLSA LQKGLEGKQA GKSRSDCREN KLEKTKGCHL YAINTHHSRE
       610        620        630        640        650        660
LRIVVAIRNK LLLITRKHNK PSGVTSTSLL SPLSESPVEE FQYIREICLS DSPMVMTLVD
       670        680        690        700        710        720
GPAEESDNLI CVAYRHQFDV VNESTGEAFR LHHVEANRVN FVAAIDVYED GEAGLLLCYN
       730        740        750        760        770        780
YSCIYKKVCP FNGGSFLVQP SASDFQFCWN QAPYAIVCAF PYLLAFTTDS MEIRLVVNGN
       790        800        810        820        830        840
LVHTAVVPQL QLVASRSDIY FTATAAVNEV SSGGSSKGAS ARNSPQTPPG RDTPVFPSSL
       850        860        870        880        890        900
GEGEIQSKNL YKIPLRNLVG RSIERPLKSP LVSKVITPPT PISVGLAAIP VTHSLSLSRM
       910        920        930        940        950        960
EIKEIASRTR RELLGLSDEG GPKSEGAPKA KSKPRKRLEE SQGGPKPGAV RSSSSDRIPS
       970        980        990       1000       1010
GSLESASTSE ANPEGHSASS DQDPVADREG SPVSGSSPFQ LTAFSDEDII DLK         10         20         30         40         50         60
MVVDFCRRFV ARSLCIILMK HFCSSSVSED LGCRRGDFSR KHYGSVELLI SSDADGAIQR
        70         80         90        100        110        120
AGRFRVENGS SDENATALPG TWRRTDVHLE NPEYHTRWYF KYFLGQVHQN YIGNDAEKSP
       130        140        150        160        170        180
FFLSVTLSDQ NNQRVPQYRA ILWRKTGTQK ICLPYSPTKT LSVKSILSAM NLDKFEKGPR
       190        200        210        220        230        240
EIFHPEIQKD LLVLEEQEGS VNFKFGVLFA KDGQLTDDEM FSNEIGSEPF QKFLNLLGDT
       250        260        270        280        290        300
ITLKGWTGYR GGLDTKNDTT GIHSVYTVYQ GHEIMFHVST MLPYSKENKQ QVERKRHIGN
       310        320        330        340        350        360
DIVTIVFQEG EESSPAFKPS MIRSHFTHIF ALVRYNQQND NYRLKIFSEE SVPLFGPPLP
       370        380        390        400        410        420
TPPVFTDHQE FRDFLLVKLI NGEKATLETP TFAQKRRRTL DMLIRSLHQD LMPDLHKNML
       430        440        450        460        470        480
NRRSFSDVLP ESPKSARKKE EARQAEFVRI GQALKLKSIV RGDAPSSLAA SGICKKEPWE
       490        500        510        520        530        540
PQCFCSNFPH EAVCADPWGQ ALLVSTDAGV LLVDDDLPSV PVFDRTLPVK QMHVLETLDL
       550        560        570        580        590        600
LVLRADKGKD ARLFVFRLSA LQKGLEGKQA GKSRSDCREN KLEKTKGCHL YAINTHHSRE
       610        620        630        640        650        660
LRIVVAIRNK LLLITRKHNK PSGVTSTSLL SPLSESPVEE FQYIREICLS DSPMVMTLVD
       670        680        690        700        710        720
GPAEESDNLI CVAYRHQFDV VNESTGEAFR LHHVEANRVN FVAAIDVYED GEAGLLLCYN
       730        740        750        760        770        780
YSCIYKKVCP FNGGSFLVQP SASDFQFCWN QAPYAIVCAF PYLLAFTTDS MEIRLVVNGN
       790        800        810        820        830        840
LVHTAVVPQL QLVASRSDIY FTATAAVNEV SSGGSSKGAS ARNSPQTPPG RDTPVFPSSL
       850        860        870        880        890        900
GEGEIQSKNL YKIPLRNLVG RSIERPLKSP LVSKVITPPT PISVGLAAIP VTHSLSLSRM
       910        920        930        940        950        960
EIKEIASRTR RELLGLSDEG GPKSEGAPKA KSKPRKRLEE SQGGPKPGAV RSSSSDRIPS
       970        980        990       1000       1010
GSLESASTSE ANPEGHSASS DQDPVADREG SPVSGSSPFQ LTAFSDEDII DLK         10         20         30         40         50         60
MVVDFCRRFV ARSLCIILMK HFCSSSVSED LGCRRGDFSR KHYGSVELLI SSDADGAIQR
        70         80         90        100        110        120
AGRFRVENGS SDENATALPG TWRRTDVHLE NPEYHTRWYF KYFLGQVHQN YIGNDAEKSP
       130        140        150        160        170        180
FFLSVTLSDQ NNQRVPQYRA ILWRKTGTQK ICLPYSPTKT LSVKSILSAM NLDKFEKGPR
       190        200        210        220        230        240
EIFHPEIQKD LLVLEEQEGS VNFKFGVLFA KDGQLTDDEM FSNEIGSEPF QKFLNLLGDT
       250        260        270        280        290        300
ITLKGWTGYR GGLDTKNDTT GIHSVYTVYQ GHEIMFHVST MLPYSKENKQ QVERKRHIGN
       310        320        330        340        350        360
DIVTIVFQEG EESSPAFKPS MIRSHFTHIF ALVRYNQQND NYRLKIFSEE SVPLFGPPLP
       370        380        390        400        410        420
TPPVFTDHQE FRDFLLVKLI NGEKATLETP TFAQKRRRTL DMLIRSLHQD LMPDLHKNML
       430        440        450        460        470        480
NRRSFSDVLP ESPKSARKKE EARQAEFVRI GQALKLKSIV RGDAPSSLAA SGICKKEPWE
       490        500        510        520        530        540
PQCFCSNFPH EAVCADPWGQ ALLVSTDAGV LLVDDDLPSV PVFDRTLPVK QMHVLETLDL
       550        560        570        580        590        600
LVLRADKGKD ARLFVFRLSA LQKGLEGKQA GKSRSDCREN KLEKTKGCHL YAINTHHSRE
       610        620        630        640        650        660
LRIVVAIRNK LLLITRKHNK PSGVTSTSLL SPLSESPVEE FQYIREICLS DSPMVMTLVD
       670        680        690        700        710        720
GPAEESDNLI CVAYRHQFDV VNESTGEAFR LHHVEANRVN FVAAIDVYED GEAGLLLCYN
       730        740        750        760        770        780
YSCIYKKVCP FNGGSFLVQP SASDFQFCWN QAPYAIVCAF PYLLAFTTDS MEIRLVVNGN
       790        800        810        820        830        840
LVHTAVVPQL QLVASRSDIY FTATAAVNEV SSGGSSKGAS ARNSPQTPPG RDTPVFPSSL
       850        860        870        880        890        900
GEGEIQSKNL YKIPLRNLVG RSIERPLKSP LVSKVITPPT PISVGLAAIP VTHSLSLSRM
       910        920        930        940        950        960
EIKEIASRTR RELLGLSDEG GPKSEGAPKA KSKPRKRLEE SQGGPKPGAV RSSSSDRIPS
       970        980        990       1000       1010
GSLESASTSE ANPEGHSASS DQDPVADREG SPVSGSSPFQ LTAFSDEDII DLK         10         20         30         40         50         60
MVVDFCRRFV ARSLCIILMK HFCSSSVSED LGCRRGDFSR KHYGSVELLI SSDADGAIQR
        70         80         90        100        110        120
AGRFRVENGS SDENATALPG TWRRTDVHLE NPEYHTRWYF KYFLGQVHQN YIGNDAEKSP
       130        140        150        160        170        180
FFLSVTLSDQ NNQRVPQYRA ILWRKTGTQK ICLPYSPTKT LSVKSILSAM NLDKFEKGPR
       190        200        210        220        230        240
EIFHPEIQKD LLVLEEQEGS VNFKFGVLFA KDGQLTDDEM FSNEIGSEPF QKFLNLLGDT
       250        260        270        280        290        300
ITLKGWTGYR GGLDTKNDTT GIHSVYTVYQ GHEIMFHVST MLPYSKENKQ QVERKRHIGN
       310        320        330        340        350        360
DIVTIVFQEG EESSPAFKPS MIRSHFTHIF ALVRYNQQND NYRLKIFSEE SVPLFGPPLP
       370        380        390        400        410        420
TPPVFTDHQE FRDFLLVKLI NGEKATLETP TFAQKRRRTL DMLIRSLHQD LMPDLHKNML
       430        440        450        460        470        480
NRRSFSDVLP ESPKSARKKE EARQAEFVRI GQALKLKSIV RGDAPSSLAA SGICKKEPWE
       490        500        510        520        530        540
PQCFCSNFPH EAVCADPWGQ ALLVSTDAGV LLVDDDLPSV PVFDRTLPVK QMHVLETLDL
       550        560        570        580        590        600
LVLRADKGKD ARLFVFRLSA LQKGLEGKQA GKSRSDCREN KLEKTKGCHL YAINTHHSRE
       610        620        630        640        650        660
LRIVVAIRNK LLLITRKHNK PSGVTSTSLL SPLSESPVEE FQYIREICLS DSPMVMTLVD
       670        680        690        700        710        720
GPAEESDNLI CVAYRHQFDV VNESTGEAFR LHHVEANRVN FVAAIDVYED GEAGLLLCYN
       730        740        750        760        770        780
YSCIYKKVCP FNGGSFLVQP SASDFQFCWN QAPYAIVCAF PYLLAFTTDS MEIRLVVNGN
       790        800        810        820        830        840
LVHTAVVPQL QLVASRSDIY FTATAAVNEV SSGGSSKGAS ARNSPQTPPG RDTPVFPSSL
       850        860        870        880        890        900
GEGEIQSKNL YKIPLRNLVG RSIERPLKSP LVSKVITPPT PISVGLAAIP VTHSLSLSRM
       910        920        930        940        950        960
EIKEIASRTR RELLGLSDEG GPKSEGAPKA KSKPRKRLEE SQGGPKPGAV RSSSSDRIPS
       970        980        990       1000       1010
GSLESASTSE ANPEGHSASS DQDPVADREG SPVSGSSPFQ LTAFSDEDII DLK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5VVW2-1-unknown	MVVDFC...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VVW2-1-unknown	MVVDFC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75716
Q5VVW2-1-unknown	MVVDFC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75717
Q5VVW2-771-unknown	MEIRLV...	771	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75718
Q5VVW2-771-unknown	MEIRLV...	771	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106982
Q5VVW2-771-unknown	MEIRLV...	771	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106983

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RRTDVH	87	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416473
...RRTDVH	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154230
...RRTDVH	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154231
...RRTDVH	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154232
...IGNDAE	116	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411160
...IGNDAE	116	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154546
...IGNDAE	116	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154547
...IGNDAE	116	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154548
...PEIQKD	189	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411329
...PEIQKD	189	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155507
...PEIQKD	189	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155508
...TITLKG	244	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400579
...IIDLK	1013	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IIDLK	1013	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71336
...IIDLK	1013	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71337

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)