TopFIND 4.0

Q5VVX9: Ubiquitin-conjugating enzyme E2 U

General Information

Protein names
- Ubiquitin-conjugating enzyme E2 U
- 2.3.2.23
- E2 ubiquitin-conjugating enzyme U
- Ubiquitin carrier protein U
- Ubiquitin-protein ligase U
Gene names UBE2U
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5VVX9

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHGRAYLLLH RDFCDLKENN YKGITAKPVS EDMMEWEVEI EGLQNSVWQG LVFQLTIHFT 
        70         80         90        100        110        120 
SEYNYAPPVV KFITIPFHPN VDPHTGQPCI DFLDNPEKWN TNYTLSSILL ALQVMLSNPV 
       130        140        150        160        170        180 
LENPVNLEAA RILVKDESLY RTILRLFNRP LQMKDDSQEL PKDPRKCIRP IKTTSFSDYY 
       190        200        210        220        230        240 
QTWSRIATSK ATEYYRTPLL KVPNFIGQYY KWKKMDLQHQ KEWNLKYSVI KCWLARKRMP 
       250        260        270        280        290        300 
HEVTHSMEEI KLCPTLIPTT DEIFLESPTA INSITDIYET EEEGWKSDTS LYENDTDEPR 
       310        320    
EEEVEDLISW TNTLNTNTSE D

Isoforms

- Isoform 2 of Ubiquitin-conjugating enzyme E2 U

Sequence View

        10         20         30         40         50         60 
MHGRAYLLLH RDFCDLKENN YKGITAKPVS EDMMEWEVEI EGLQNSVWQG LVFQLTIHFT 
        70         80         90        100        110        120 
SEYNYAPPVV KFITIPFHPN VDPHTGQPCI DFLDNPEKWN TNYTLSSILL ALQVMLSNPV 
       130        140        150        160        170        180 
LENPVNLEAA RILVKDESLY RTILRLFNRP LQMKDDSQEL PKDPRKCIRP IKTTSFSDYY 
       190        200        210        220        230        240 
QTWSRIATSK ATEYYRTPLL KVPNFIGQYY KWKKMDLQHQ KEWNLKYSVI KCWLARKRMP 
       250        260        270        280        290        300 
HEVTHSMEEI KLCPTLIPTT DEIFLESPTA INSITDIYET EEEGWKSDTS LYENDTDEPR 
       310        320    
EEEVEDLISW TNTLNTNTSE D



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Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q5VVX9-1-unknown MHGRAY... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q5VVX9-1-unknown MHGRAY... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93604

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EWNLKY 226 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89222
    ...NTSED 321 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)