TopFIND 4.0

Q60641: Bile acid receptor

General Information

Protein names
- Bile acid receptor
- Farnesoid X-activated receptor
- Farnesol receptor HRR-1
- Nuclear receptor subfamily 1 group H member 4
- Retinoid X receptor-interacting protein 14
- RXR-interacting protein 14
Gene names Nr1h4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q60641

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVMQFQGLEN PIQISLHHSH RLSGFVPEGM SVKPAKGMLT EHAAGPLGQN LDLESYSPYN 
        70         80         90        100        110        120 
NVPFPQVQPQ ISSSSYYSNL GFYPQQPEDW YSPGIYELRR MPAETGYQGE TEVSEMPVTK 
       130        140        150        160        170        180 
KPRMAAASAG RIKGDELCVV CGDRASGYHY NALTCEGCKG FFRRSITKNA VYKCKNGGNC 
       190        200        210        220        230        240 
VMDMYMRRKC QECRLRKCKE MGMLAECMYT GLLTEIQCKS KRLRKNVKQH ADQTANEDDS 
       250        260        270        280        290        300 
EGRDLRQVTS TTKFCREKTE LTADQQTLLD YIMDSYNKQR MPQEITNKIL KEEFSAEENF 
       310        320        330        340        350        360 
LILTEMATSH VQILVEFTKK LPGFQTLDHE DQIALLKGSA VEAMFLRSAE IFNKKLPAGH 
       370        380        390        400        410        420 
ADLLEERIRK SGISDEYITP MFSFYKSVGE LKMTQEEYAL LTAIVILSPD RQYIKDREAV 
       430        440        450        460        470        480 
EKLQEPLLDV LQKLCKMYQP ENPQHFACLL GRLTELRTFN HHHAEMLMSW RVNDHKFTPL 
   
LCEIWDVQ

Isoforms

- Isoform 2 of Bile acid receptor - Isoform 3 of Bile acid receptor - Isoform 4 of Bile acid receptor

Sequence View

        10         20         30         40         50         60 
MVMQFQGLEN PIQISLHHSH RLSGFVPEGM SVKPAKGMLT EHAAGPLGQN LDLESYSPYN 
        70         80         90        100        110        120 
NVPFPQVQPQ ISSSSYYSNL GFYPQQPEDW YSPGIYELRR MPAETGYQGE TEVSEMPVTK 
       130        140        150        160        170        180 
KPRMAAASAG RIKGDELCVV CGDRASGYHY NALTCEGCKG FFRRSITKNA VYKCKNGGNC 
       190        200        210        220        230        240 
VMDMYMRRKC QECRLRKCKE MGMLAECMYT GLLTEIQCKS KRLRKNVKQH ADQTANEDDS 
       250        260        270        280        290        300 
EGRDLRQVTS TTKFCREKTE LTADQQTLLD YIMDSYNKQR MPQEITNKIL KEEFSAEENF 
       310        320        330        340        350        360 
LILTEMATSH VQILVEFTKK LPGFQTLDHE DQIALLKGSA VEAMFLRSAE IFNKKLPAGH 
       370        380        390        400        410        420 
ADLLEERIRK SGISDEYITP MFSFYKSVGE LKMTQEEYAL LTAIVILSPD RQYIKDREAV 
       430        440        450        460        470        480 
EKLQEPLLDV LQKLCKMYQP ENPQHFACLL GRLTELRTFN HHHAEMLMSW RVNDHKFTPL 
   
LCEIWDVQ         10         20         30         40         50         60 
MVMQFQGLEN PIQISLHHSH RLSGFVPEGM SVKPAKGMLT EHAAGPLGQN LDLESYSPYN 
        70         80         90        100        110        120 
NVPFPQVQPQ ISSSSYYSNL GFYPQQPEDW YSPGIYELRR MPAETGYQGE TEVSEMPVTK 
       130        140        150        160        170        180 
KPRMAAASAG RIKGDELCVV CGDRASGYHY NALTCEGCKG FFRRSITKNA VYKCKNGGNC 
       190        200        210        220        230        240 
VMDMYMRRKC QECRLRKCKE MGMLAECMYT GLLTEIQCKS KRLRKNVKQH ADQTANEDDS 
       250        260        270        280        290        300 
EGRDLRQVTS TTKFCREKTE LTADQQTLLD YIMDSYNKQR MPQEITNKIL KEEFSAEENF 
       310        320        330        340        350        360 
LILTEMATSH VQILVEFTKK LPGFQTLDHE DQIALLKGSA VEAMFLRSAE IFNKKLPAGH 
       370        380        390        400        410        420 
ADLLEERIRK SGISDEYITP MFSFYKSVGE LKMTQEEYAL LTAIVILSPD RQYIKDREAV 
       430        440        450        460        470        480 
EKLQEPLLDV LQKLCKMYQP ENPQHFACLL GRLTELRTFN HHHAEMLMSW RVNDHKFTPL 
   
LCEIWDVQ         10         20         30         40         50         60 
MVMQFQGLEN PIQISLHHSH RLSGFVPEGM SVKPAKGMLT EHAAGPLGQN LDLESYSPYN 
        70         80         90        100        110        120 
NVPFPQVQPQ ISSSSYYSNL GFYPQQPEDW YSPGIYELRR MPAETGYQGE TEVSEMPVTK 
       130        140        150        160        170        180 
KPRMAAASAG RIKGDELCVV CGDRASGYHY NALTCEGCKG FFRRSITKNA VYKCKNGGNC 
       190        200        210        220        230        240 
VMDMYMRRKC QECRLRKCKE MGMLAECMYT GLLTEIQCKS KRLRKNVKQH ADQTANEDDS 
       250        260        270        280        290        300 
EGRDLRQVTS TTKFCREKTE LTADQQTLLD YIMDSYNKQR MPQEITNKIL KEEFSAEENF 
       310        320        330        340        350        360 
LILTEMATSH VQILVEFTKK LPGFQTLDHE DQIALLKGSA VEAMFLRSAE IFNKKLPAGH 
       370        380        390        400        410        420 
ADLLEERIRK SGISDEYITP MFSFYKSVGE LKMTQEEYAL LTAIVILSPD RQYIKDREAV 
       430        440        450        460        470        480 
EKLQEPLLDV LQKLCKMYQP ENPQHFACLL GRLTELRTFN HHHAEMLMSW RVNDHKFTPL 
   
LCEIWDVQ



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q60641-1-unknown MVMQFQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q60641-1-unknown MVMQFQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83186

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IWDVQ 488 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IWDVQ 488 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78804

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)