TopFIND 4.0

Q60715: Prolyl 4-hydroxylase subunit alpha-1

General Information

Protein names
- Prolyl 4-hydroxylase subunit alpha-1
- 4-PH alpha-1
- 1.14.11.2
- Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1
Gene names P4ha1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q60715

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MIWVVLMMAI LLPQSLAHPG FFTSIGQMTD LIHNEKDLVT SLKDYIKAEE DKLEQIKKWA 
        70         80         90        100        110        120 
EKLDRLTSTA TKDPEGFVGH PVNAFKLMKR LNTEWSELEN LILKDMSDGF ISNLTIQRQY 
       130        140        150        160        170        180 
FPNDEDQVGA AKALFRLQDT YNLDTNTISK GNLPGVQHKS FLTAEDCFEL GKVAYTEADY 
       190        200        210        220        230        240 
YHTELWMEQA LTQLEEGELS TVDKVSVLDY LSYAVYQQGD LDKALLLTKK LLELDPEHQR 
       250        260        270        280        290        300 
ANGNLVYFEY IMSKEKDANK SASGDQSDQK TAPKKKGIAV DYLPERQKYE MLCRGEGIKM 
       310        320        330        340        350        360 
TPRRQKRLFC RYHDGNRNPK FILAPAKQED EWDKPRIIRF HDIISDAEIE IVKDLAKPRL 
       370        380        390        400        410        420 
RRATISNPVT GALETVHYRI SKSAWLSGYE DPVVSRINMR IQDLTGLDVS TAEELQVANY 
       430        440        450        460        470        480 
GVGGQYEPHF DFARKDEPDA FRELGTGNRI ATWLFYMSDV SAGGATVFPE VGASVWPKKG 
       490        500        510        520        530    
TAVFWYNLFA SGEGDYSTRH AACPVLVGNK WVSNKWLHER GQEFRRPCTL SELE

Isoforms

- Isoform 2 of Prolyl 4-hydroxylase subunit alpha-1

Sequence View

        10         20         30         40         50         60 
MIWVVLMMAI LLPQSLAHPG FFTSIGQMTD LIHNEKDLVT SLKDYIKAEE DKLEQIKKWA 
        70         80         90        100        110        120 
EKLDRLTSTA TKDPEGFVGH PVNAFKLMKR LNTEWSELEN LILKDMSDGF ISNLTIQRQY 
       130        140        150        160        170        180 
FPNDEDQVGA AKALFRLQDT YNLDTNTISK GNLPGVQHKS FLTAEDCFEL GKVAYTEADY 
       190        200        210        220        230        240 
YHTELWMEQA LTQLEEGELS TVDKVSVLDY LSYAVYQQGD LDKALLLTKK LLELDPEHQR 
       250        260        270        280        290        300 
ANGNLVYFEY IMSKEKDANK SASGDQSDQK TAPKKKGIAV DYLPERQKYE MLCRGEGIKM 
       310        320        330        340        350        360 
TPRRQKRLFC RYHDGNRNPK FILAPAKQED EWDKPRIIRF HDIISDAEIE IVKDLAKPRL 
       370        380        390        400        410        420 
RRATISNPVT GALETVHYRI SKSAWLSGYE DPVVSRINMR IQDLTGLDVS TAEELQVANY 
       430        440        450        460        470        480 
GVGGQYEPHF DFARKDEPDA FRELGTGNRI ATWLFYMSDV SAGGATVFPE VGASVWPKKG 
       490        500        510        520        530    
TAVFWYNLFA SGEGDYSTRH AACPVLVGNK WVSNKWLHER GQEFRRPCTL SELE



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LSELE 534 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LSELE 534 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79660

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)