TopFIND 4.0

Q60716: Prolyl 4-hydroxylase subunit alpha-2

General Information

Protein names
- Prolyl 4-hydroxylase subunit alpha-2
- 4-PH alpha-2
- 1.14.11.2
- Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2
Gene names P4ha2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q60716

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLQVLVLVL LMSWFGVLSW VQAEFFTSIG HMTDLIYAEK DLVQSLKEYI LVEEAKLAKI 
        70         80         90        100        110        120 
KSWASKMEAL TSRSAADPEG YLAHPVNAYK LVKRLNTDWP ALGDLVLQDA SAGFVANLSV 
       130        140        150        160        170        180 
QRQFFPTDED ESGAARALMR LQDTYKLDPD TISRGELPGT KYQAMLSVDD CFGLGRSAYN 
       190        200        210        220        230        240 
EGDYYHTVLW MEQVLKQLDA GEEATVTKSL VLDYLSYAVF QLGDLHRAVE LTRRLLSLDP 
       250        260        270        280        290        300 
SHERAGGNLR YFERLLEEER GKSLSNQTDA GLATQENLYE RPTDYLPERD VYESLCRGEG 
       310        320        330        340        350        360 
VKLTPRRQKK LFCRYHHGNR VPQLLIAPFK EEDEWDSPHI VRYYDVMSDE EIERIKEIAK 
       370        380        390        400        410        420 
PKLARATVRD PKTGVLTVAS YRVSKSSWLE EDDDPVVARV NRRMQHITGL TVKTAELLQV 
       430        440        450        460        470        480 
ANYGMGGQYE PHFDFSRSDD EDAFKRLGTG NRVATFLNYM SDVEAGGATV FPDLGAAIWP 
       490        500        510        520        530    
KKGTAVFWYN LLRSGEGDYR TRHAACPVLV GCKWVSNKWF HERGQEFLRP CGTTEVD

Isoforms

- Isoform IIa of Prolyl 4-hydroxylase subunit alpha-2

Sequence View

        10         20         30         40         50         60 
MKLQVLVLVL LMSWFGVLSW VQAEFFTSIG HMTDLIYAEK DLVQSLKEYI LVEEAKLAKI 
        70         80         90        100        110        120 
KSWASKMEAL TSRSAADPEG YLAHPVNAYK LVKRLNTDWP ALGDLVLQDA SAGFVANLSV 
       130        140        150        160        170        180 
QRQFFPTDED ESGAARALMR LQDTYKLDPD TISRGELPGT KYQAMLSVDD CFGLGRSAYN 
       190        200        210        220        230        240 
EGDYYHTVLW MEQVLKQLDA GEEATVTKSL VLDYLSYAVF QLGDLHRAVE LTRRLLSLDP 
       250        260        270        280        290        300 
SHERAGGNLR YFERLLEEER GKSLSNQTDA GLATQENLYE RPTDYLPERD VYESLCRGEG 
       310        320        330        340        350        360 
VKLTPRRQKK LFCRYHHGNR VPQLLIAPFK EEDEWDSPHI VRYYDVMSDE EIERIKEIAK 
       370        380        390        400        410        420 
PKLARATVRD PKTGVLTVAS YRVSKSSWLE EDDDPVVARV NRRMQHITGL TVKTAELLQV 
       430        440        450        460        470        480 
ANYGMGGQYE PHFDFSRSDD EDAFKRLGTG NRVATFLNYM SDVEAGGATV FPDLGAAIWP 
       490        500        510        520        530    
KKGTAVFWYN LLRSGEGDYR TRHAACPVLV GCKWVSNKWF HERGQEFLRP CGTTEVD



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q60716-1-unknown MKLQVL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt84044
    Q60716-24-unknown EFFTSI... 24 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q60716-24-unknown EFFTSI... 24 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113422

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TTEVD 537 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TTEVD 537 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79662

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)