TopFIND 4.0

Q60829: Protein phosphatase 1 regulatory subunit 1B

General Information

Protein names
- Protein phosphatase 1 regulatory subunit 1B
- DARPP-32
- Dopamine- and cAMP-regulated neuronal phosphoprotein
Gene names Ppp1r1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q60829

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPKDRKKIQ FSVPAPPSQL DPRQVEMIRR RRPTPAMLFR VSEHSSPEEE ASPHQRTSGE 
        70         80         90        100        110        120 
GHHPKSKRPN PCAYTPPSLK AVQHLQTISN LSENQASEEE DELGELRELG YPQEDDEEDE 
       130        140        150        160        170        180 
DEEEDEEEDS QAEVLKGSRG TVGQKPTCGR GLEGPWERPP PLDEPQRDGN SEDQVEGRAT 
       190    
LSEPGEEPQH PSPP

Isoforms

- Isoform 2 of Protein phosphatase 1 regulatory subunit 1B

Sequence View

        10         20         30         40         50         60 
MDPKDRKKIQ FSVPAPPSQL DPRQVEMIRR RRPTPAMLFR VSEHSSPEEE ASPHQRTSGE 
        70         80         90        100        110        120 
GHHPKSKRPN PCAYTPPSLK AVQHLQTISN LSENQASEEE DELGELRELG YPQEDDEEDE 
       130        140        150        160        170        180 
DEEEDEEEDS QAEVLKGSRG TVGQKPTCGR GLEGPWERPP PLDEPQRDGN SEDQVEGRAT 
       190    
LSEPGEEPQH PSPP



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q60829-1-Acetylation MDPKDR... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q60829-37-unknown MLFRVS... 37 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86014

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HPSPP 194 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HPSPP 194 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt81632

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)