TopFIND 4.0

Q60991: 25-hydroxycholesterol 7-alpha-hydroxylase

General Information

Protein names
- 25-hydroxycholesterol 7-alpha-hydroxylase
- 1.14.14.29 {ECO:0000269|PubMed:9295351}
- Cytochrome P450 7B1
- Hippocampal transcript 1 protein
- HCT-1
- Oxysterol 7-alpha-hydroxylase
Gene names Cyp7b1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q60991

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQGATTLDAA SPGPLALLGL LFAATLLLSA LFLLTRRTRR PREPPLIKGW LPYLGMALKF 
        70         80         90        100        110        120 
FKDPLTFLKT LQRQHGDTFT VFLVGKYITF VLNPFQYQYV TKNPKQLSFQ KFSSRLSAKA 
       130        140        150        160        170        180 
FSVKKLLTDD DLNEDVHRAY LLLQGKPLDA LLETMIQEVK ELFESQLLKI TDWNTERIFA 
       190        200        210        220        230        240 
FCGSLVFEIT FATLYGKILA GNKKQIISEL RDDFFKFDDM FPYLVSDIPI QLLRNEESMQ 
       250        260        270        280        290        300 
KKIIKCLTSE KVAQMQGQSK IVQERQDLLK RYYRHDDPEI GAHHLGFLWA SLANTIPAMF 
       310        320        330        340        350        360 
WAMYYILRHP EAMEALRDEI DSFLQSTGQK KGPGISVHFT REQLDSLVCL ESTILEVLRL 
       370        380        390        400        410        420 
CSYSSIIREV QEDMNLSLES KSFSLRKGDF VALFPPLIHN DPEIFDAPKE FRFDRFIEDG 
       430        440        450        460        470        480 
KKKSTFFKGG KKLKTYVMPF GLGTSKCPGR YFAVNEMKLL LIMLLTYFDL EIIDRKPIGL 
       490        500    
NHSRMFLGIQ HPDSAVSFRY KAKSWRS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q60991-1-unknown MQGATT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KSWRS 507 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)