TopFIND 4.0

Q61481: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

General Information

Protein names
- Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
- Cam-PDE 1A
- 3.1.4.17
- 61 kDa Cam-PDE
Gene names Pde1a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q61481

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MCDSSPSSSH VWIAPVRNII MGSTDTDIEE LENATYKYLI GEQTEKMWQR LKGILRCLVK 
        70         80         90        100        110        120 
QLEKGDVNVV DLKKNIEYAA SVLEAVYIDE TRRLLDTEDE LSDIQTDSVP SEVRDWLAST 
       130        140        150        160        170        180 
FTRKMGMMKK KPEEKPKFRS IVHAVQAGIF VERMYRKNYH MVGLTYPAAV IVTLKEVDKW 
       190        200        210        220        230        240 
SFDVFALNEA SGEHSLKFMI YELFTRYDLI NRFKIPVSCL IAFAEALEVG YSKHKNPYHN 
       250        260        270        280        290        300 
LVHAADVTQT VHYIMLHTGI MHWLTELEIL AMVFAAAIHD YEHTGTTNNF HIQTRSDVAI 
       310        320        330        340        350        360 
LYNDRSVLEN HHVSAAYRLM QEEEMNILVN LSKDDWRDLR NLVIEMVLAT DMSGHFQQIK 
       370        380        390        400        410        420 
NIRNSLQQPE GIDRAKTMSL ILHAADISHP AKTWKLHYRW TMALMEEFFL QGDKEAELGL 
       430        440        450        460        470        480 
PFSPLCDRKS TMVAQSQIGF IDFIVEPTFS LLTDSTEKIV IPLIEEASKS QSSNYGASSS 
       490        500        510        520        530        540 
STMIGFHVAD SLRRSNTKGS VCDGSYAPDY SLSAVDLKSF KNNLVDIIQQ NKERWKELAA 
       550        560    
QGELDLHKNS EELGNTEEKH ADTRP

Isoforms

- Isoform PDE1A1 of Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

Sequence View

        10         20         30         40         50         60 
MCDSSPSSSH VWIAPVRNII MGSTDTDIEE LENATYKYLI GEQTEKMWQR LKGILRCLVK 
        70         80         90        100        110        120 
QLEKGDVNVV DLKKNIEYAA SVLEAVYIDE TRRLLDTEDE LSDIQTDSVP SEVRDWLAST 
       130        140        150        160        170        180 
FTRKMGMMKK KPEEKPKFRS IVHAVQAGIF VERMYRKNYH MVGLTYPAAV IVTLKEVDKW 
       190        200        210        220        230        240 
SFDVFALNEA SGEHSLKFMI YELFTRYDLI NRFKIPVSCL IAFAEALEVG YSKHKNPYHN 
       250        260        270        280        290        300 
LVHAADVTQT VHYIMLHTGI MHWLTELEIL AMVFAAAIHD YEHTGTTNNF HIQTRSDVAI 
       310        320        330        340        350        360 
LYNDRSVLEN HHVSAAYRLM QEEEMNILVN LSKDDWRDLR NLVIEMVLAT DMSGHFQQIK 
       370        380        390        400        410        420 
NIRNSLQQPE GIDRAKTMSL ILHAADISHP AKTWKLHYRW TMALMEEFFL QGDKEAELGL 
       430        440        450        460        470        480 
PFSPLCDRKS TMVAQSQIGF IDFIVEPTFS LLTDSTEKIV IPLIEEASKS QSSNYGASSS 
       490        500        510        520        530        540 
STMIGFHVAD SLRRSNTKGS VCDGSYAPDY SLSAVDLKSF KNNLVDIIQQ NKERWKELAA 
       550        560    
QGELDLHKNS EELGNTEEKH ADTRP



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q61481-1-unknown MCDSSP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ADTRP 565 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ADTRP 565 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt80281

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)