Q61687: Transcriptional regulator ATRX

General Information

Protein names	- Transcriptional regulator ATRX - 3.6.4.12 - ATP-dependent helicase ATRX - HP1 alpha-interacting protein - HP1-BP38 protein - Heterochromatin protein 2 - X-linked nuclear protein
Gene names	Atrx
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61687

3 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTAEPMSGNK LSTLVQKLHD FLAHSSEESE ETCSSPRLVM NQSTDKICGS GLNSDMMENN
        70         80         90        100        110        120
KEEGASTSEK SRSSGSSRSK RKPSIVTKYV ESDDEKPTDE NVNEKAATEN SENDITMQSL
       130        140        150        160        170        180
PKGTVIVQPE PVLNEDKDDF KGPEFRSRSK MKADNLKKRG EDGLHGIVSC TACGQQVNHF
       190        200        210        220        230        240
QKDSIYRHPS LKVLICKNCF KYYMSDDISR DSDGMDEQCR WCAEGGNLIC CDFCHNAFCK
       250        260        270        280        290        300
KCILRNLGRK ELSTIMDENN QWYCYICQPE PLLDLVTACN SVFENLEQLL QQNKKKIKVD
       310        320        330        340        350        360
SEKTSKVCDQ TSKFSPKKSS SSCNGEEKKL EESCSGSVSS TYSHSALSVP KEMIKKTTKL
       370        380        390        400        410        420
IETTSNMNSS YIKFLKQAAD NSEMTSAMKL CQLKSFKSVL DDIKKAHLAL EEDLNSEIQA
       430        440        450        460        470        480
LDDVHKEKNT KDLKSTDAKS ETKLGKGEKS YSTEKREFLK LDARSSVKAI DGEEQRAHKS
       490        500        510        520        530        540
TSGEHKGSGR KDGSQYEPTN TPEDLDMDIV SVPSSVPEDI FDSLESAMEV QSSADYQGDG
       550        560        570        580        590        600
NSGTEPELES SSVKLNVSSK DSRGNIKSKV TAKVRKELFV KLTPVSLSNS PIKGVDCQEV
       610        620        630        640        650        660
SQEKNGRKSS GVARSSEKCR PREEISDHEN NVTILLEDSD LRRSPRVKTT PLRRQTESNP
       670        680        690        700        710        720
AMSNSDEESN GTMKEKQKMS GPIRKKDKRN SADCATDNPK PHKVPKAKQP VIGDQNSDSD
       730        740        750        760        770        780
EMLAVLKEAS QMGHSSSSDT DINEPQMNHK GKTGKDDNGK RKRKNSTSGS DFDTKKGKST
       790        800        810        820        830        840
ETSIISKKKR QNYSESSNYD SELEREIKTM SRIGAARKSV PEKKEEDSSE DEKQGKKVVD
       850        860        870        880        890        900
NGGHERAKTT QEGSSADDTG DTEGRQGGSC SIAGGSIEKV RSGVEFREML CKPGVSSDGA
       910        920        930        940        950        960
EKPSVKEENV NSPEDKRVSK TKEKTKHLRS RQSRKGKGGS SDGTDRFPKK EQSDESSEGE
       970        980        990       1000       1010       1020
KKQSRQRPGT KGKKAPDLKG ETLKREQEWD SSSDGTERLP EEEEIGPFSK GIKQSKTDTA
      1030       1040       1050       1060       1070       1080
GGEKKGKKWK DKSCEKKEEL SDSVDKLPGK GDSCDSSEDK KTRNRVSLRE KKRFSLPAKS
      1090       1100       1110       1120       1130       1140
PGKRPECSSS DTEKSLKGQC CDSTEKRPKR IDLRERRNSS SKRNTKEVKS ASSSSDAEGS
      1150       1160       1170       1180       1190       1200
SEDNKKQKKQ RTSAKKKTGN TKEKKRNSLR ATPKRKQVDI TSSSSDIGDD DQNSAGEESS
      1210       1220       1230       1240       1250       1260
DEQKIKPVTE NLVLPSHTGF CQSSGDEALS KSVPATVDDD DDDNDPENRI AKKMLLEEIK
      1270       1280       1290       1300       1310       1320
ANLSSDEDGS SDDEPDGGGK KRIGKQSEES PADDGELRRE QLAVNQVNSE SDSDSEESKK
      1330       1340       1350       1360       1370       1380
PRYRHRLLRH KLTLSDGESG EEKPTKPKEH KEAKGRNRRK VSSEDSEDTD FQESGVSEEV
      1390       1400       1410       1420       1430       1440
SESEDEQRPR TRSAKKAELE ENQRSYKQKK KRRRIKVQED SSSENKSHSE EDKKEGDEED
      1450       1460       1470       1480       1490       1500
EEDEDEDEED ENDDSKSPGK GRKKIRKILK DDKLRTETQN ALKEEEERRK RIAERERERE
      1510       1520       1530       1540       1550       1560
KLREVIEIED ASPTKCPITT KLVLDENEET KEPLVQVHRN MVIKLKPHQV DGVQFMWDCC
      1570       1580       1590       1600       1610       1620
CESVEKTKKS PGSGCILAHC MGLGKTLQVV SFLHTVLLCD KLDFSTALVV CPLNTALNWM
      1630       1640       1650       1660       1670       1680
NEFEKWQEGL NDNEKLEVSE LATVKRPQER SYMLQRWQED GGVMIIGYEM YRNLAQGRNV
      1690       1700       1710       1720       1730       1740
KSRKLKDIFN KALVDPGPDF VVCDEGHILK NEASAVSKAM NSIKSRRRII LTGTPLQNNL
      1750       1760       1770       1780       1790       1800
IEYHCMVNFI KENLLGSIKE FRNRFINPIQ NGQCADSTMV DVRVMKKRAH ILYEMLAGCV
      1810       1820       1830       1840       1850       1860
QRKDYTALTK FLPPKHEYVL AVRMTAIQCK LYQYYLDHLT GVGNSTEGGR GKAGAKLFQD
      1870       1880       1890       1900       1910       1920
FQMLSRIWTH PWCLQLDYIS KENKGYFDED SMDEFIASDS DETSKSLSSD EKKKPKGKKG
      1930       1940       1950       1960       1970       1980
KKDSSSSGSG SDNDVEVIKV WNSRSRGGGD GNVDDTGNNP SVSLKLDESK TTSTSNPSSP
      1990       2000       2010       2020       2030       2040
APDWYKDFVT DTDAEVLEHS GKMVLLFEIL RMAEEIGDKV LVFSQSLISL DLIEDFLELA
      2050       2060       2070       2080       2090       2100
SREKTEDKEK PLIYKGEGKW IRNIDYYRLD GSTNAQSRKK WAEEFNDETN VRGRLFIIST
      2110       2120       2130       2140       2150       2160
KAGSLGINLV AANRVIIFDA SWNPSYDIQS IFRVYRFGQT KPVYVYRFLA QGTMEDKIYD
      2170       2180       2190       2200       2210       2220
RQVTKQSLSF RVVDQQQVER HFTMNELTEL YTFEPDLLDD PNSEKKKKRD TPMLPKDTIL
      2230       2240       2250       2260       2270       2280
AELLQIHKEH IVGYHEHDSL LDHKEEEELT EEERKAAWAE YEAEKKGLTM RFNIPTGTNL
      2290       2300       2310       2320       2330       2340
PPVTFTSQTP YIPFNLGALS AMSNQQLEDL INQGREKVVE ATNSMTAVRI QPLEDIISTV
      2350       2360       2370       2380       2390       2400
WKENMNLSEA QVQALALSRQ ASQELDVKRR EAIYNDVLTK QQMLINCVQR ILMNRRLQQQ
      2410       2420       2430       2440       2450       2460
YTQQQQQQLT YQQATLSHLM MPKPPNLIMT PSNYQQIDMR GMYQSVAGGM QPPPLQRAPP
      2470
PTVRSKNPGP SPGKSM

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q61687-1-unknown	MTAEPM...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61687-40-unknown	MNQSTD...	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123085
Q61687-40-unknown	MNQSTD...	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122034
Q61687-40-unknown	MNQSTD...	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117528
Q61687-56-unknown	MMENNK...	56	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122875
Q61687-56-unknown	MMENNK...	56	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121291
Q61687-56-unknown	MMENNK...	56	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120246

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KPTDEN	100	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117528
...FKGPEF	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120246
...NQWYCY	264	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121291
...EEKKLE	330	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122875
...ALDDVH	424	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123085
...ALDDVH	424	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122034
...KDKSCE	1034	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121416
...PGKSM	2476	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)