Q61699: Heat shock protein 105 kDa

General Information

Protein names	- Heat shock protein 105 kDa - 42 degrees C-HSP - Heat shock 110 kDa protein - Heat shock-related 100 kDa protein E7I - HSP-E7I
Gene names	Hsph1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61699

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVVGLDVGS QSCYIAVARA GGIETIANEF SDRCTPSVIS FGSKNRTIGV AAKNQQITHA
        70         80         90        100        110        120
NNTVSSFKRF HGRAFNDPFI QKEKENLSYD LVPMKNGGVG IKVMYMDEEH FFSVEQITAM
       130        140        150        160        170        180
LLTKLKETAE NNLKKPVTDC VISVPSFFTD AERRSVLDAA QIVGLNCLRL MNDMTAVALN
       190        200        210        220        230        240
YGIYKQDLPN AEEKPRVVVF VDMGHSSFQV SACAFNKGKL KVLGTAFDPF LGGKNFDEKL
       250        260        270        280        290        300
VEHFCAEFKT KYKLDAKSKI RALLRLHQEC EKLKKLMSSN STDLPLNIEC FMNDKDVSGK
       310        320        330        340        350        360
MNRSQFEELC AELLQKIEVP LHSLMAQTQL KAEDVSAIEI VGGATRIPAV KERIAKFFGK
       370        380        390        400        410        420
DVSTTLNADE AVARGCALQC AILSPAFKVR EFSVTDAVPF PISLVWNHDS EETEGVHEVF
       430        440        450        460        470        480
SRNHAAPFSK VLTFLRRGPF ELEAFYSDPQ GVPYPEAKIG RFVVQNVSAQ KDGEKSRVKV
       490        500        510        520        530        540
KVRVNTHGIF TISTASMVEK VPTEEEDGSS LEADMECPNQ RPTESSDVDK NIQQDNSEAG
       550        560        570        580        590        600
TQPQVQTDGQ QTSQSPPSPE LTSEESKTPD ADKANEKKVD QPPEAKKPKI KVVNVELPVE
       610        620        630        640        650        660
ANLVWQLGRD LLNMYIETEG KMIMQDKLEK ERNDAKNAVE ECVYEFRDKL CGPYEKFICE
       670        680        690        700        710        720
QEHEKFLRLL TETEDWLYEE GEDQAKQAYI DKLEELMKMG TPVKVRFQEA EERPKVLEEL
       730        740        750        760        770        780
GQRLQHYAKI AADFRGKDEK YNHIDESEMK KVEKSVNEVM EWMNNVMNAQ AKRSLDQDPV
       790        800        810        820        830        840
VRTHEIRAKV KELNNVCEPV VTQPKPKIES PKLERTPNGP NIDKKEDLEG KNNLGAEAPH
       850
QNGECHPNEK GSVNMDLD

Isoforms

- Isoform HSP105-beta of Heat shock protein 105 kDa

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q61699-2-unknown	MSVVGL...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61699-2-unknown	MSVVGL...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61699-1-unknown	MSVVGL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77278
Q61699-2-Acetylation	SVVGLD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61699-2-Acetylation	SVVGLD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110896
Q61699-2-Acetylation	SVVGLD...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61699-338-unknown	IEIVGG...	338		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30524
Q61699-338-unknown	IEIVGG...	338		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150679
Q61699-381-unknown	AILSPA...	381		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30526
Q61699-381-unknown	AILSPA...	381		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151641
Q61699-463-unknown	VVQNVS...	463		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30528
Q61699-463-unknown	VVQNVS...	463		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152944

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EDVSAI	337	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30524
...EDVSAI	337	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134077
...CALQCA	380	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30526
...CALQCA	380	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135043
...KIGRFV	462	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30528
...KIGRFV	462	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136370
...NMDLD	858	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NMDLD	858	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72896

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	337	VSAI.\|.IEIV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> HS105_MOUSE @337
CATE_MOUSE	380	LQCA.\|.AILS	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> HS105_MOUSE @380
CATE_MOUSE	462	GRFV.\|.VVQN	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> HS105_MOUSE @462

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)