TopFIND 4.0

Q61749: Translation initiation factor eIF-2B subunit delta

General Information

Protein names
- Translation initiation factor eIF-2B subunit delta
- eIF-2B GDP-GTP exchange factor subunit delta
Gene names Eif2b4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q61749

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI 
        70         80         90        100        110        120 
GSAVSAAQRQ DPIRELPGPG SQLGGTAGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG 
       130        140        150        160        170        180 
EQGGVPPQAC PSTAGETTSG VKRVPEHTPA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL 
       190        200        210        220        230        240 
FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLI SGSNARCIAL LHALQQVIQD 
       250        260        270        280        290        300 
YTTPPSEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF LTKEVTGMSS SKREEEAKSE 
       310        320        330        340        350        360 
LREALDRYVQ EKIVLAAQAI SRFASTKISD GDVILVYGCS SLVSRILQEA RVEGRRFRVV 
       370        380        390        400        410        420 
VVDSRPRLEG RHMLHSLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG 
       430        440        450        460        470        480 
TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVALANWQSH 
       490        500        510        520    
PSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ

Isoforms

- Isoform 2 of Translation initiation factor eIF-2B subunit delta - Isoform 2 of Translation initiation factor eIF-2B subunit delta

Sequence View

        10         20         30         40         50         60 
MAAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI 
        70         80         90        100        110        120 
GSAVSAAQRQ DPIRELPGPG SQLGGTAGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG 
       130        140        150        160        170        180 
EQGGVPPQAC PSTAGETTSG VKRVPEHTPA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL 
       190        200        210        220        230        240 
FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLI SGSNARCIAL LHALQQVIQD 
       250        260        270        280        290        300 
YTTPPSEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF LTKEVTGMSS SKREEEAKSE 
       310        320        330        340        350        360 
LREALDRYVQ EKIVLAAQAI SRFASTKISD GDVILVYGCS SLVSRILQEA RVEGRRFRVV 
       370        380        390        400        410        420 
VVDSRPRLEG RHMLHSLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG 
       430        440        450        460        470        480 
TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVALANWQSH 
       490        500        510        520    
PSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ         10         20         30         40         50         60 
MAAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI 
        70         80         90        100        110        120 
GSAVSAAQRQ DPIRELPGPG SQLGGTAGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG 
       130        140        150        160        170        180 
EQGGVPPQAC PSTAGETTSG VKRVPEHTPA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL 
       190        200        210        220        230        240 
FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLI SGSNARCIAL LHALQQVIQD 
       250        260        270        280        290        300 
YTTPPSEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF LTKEVTGMSS SKREEEAKSE 
       310        320        330        340        350        360 
LREALDRYVQ EKIVLAAQAI SRFASTKISD GDVILVYGCS SLVSRILQEA RVEGRRFRVV 
       370        380        390        400        410        420 
VVDSRPRLEG RHMLHSLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG 
       430        440        450        460        470        480 
TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVALANWQSH 
       490        500        510        520    
PSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KSSDQ 524 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KSSDQ 524 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69375

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)