Q61824: Disintegrin and metalloproteinase domain-containing protein 12

General Information

Protein names	- Disintegrin and metalloproteinase domain-containing protein 12 - ADAM 12 - 3.4.24.- - Meltrin-alpha
Gene names	Adam12
Organism	Mus musculus
Protease Family
Protease ID	M12.212
Chromosome location
UniProt ID	Q61824

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAERPARRAP PARALLLALA GALLAPRAAR GMSLWDQRGT YEVARASLLS KDPGIPGQSI
        70         80         90        100        110        120
PAKDHPDVLT VQLQLESRDL ILSLERNEGL IANGFTETHY LQDGTDVSLT RNHTDHCYYH
       130        140        150        160        170        180
GHVQGDAASV VSLSTCSGLR GLIMFENKTY SLEPMKNTTD SYKLVPAESM TNIQGLCGSQ
       190        200        210        220        230        240
HNKSNLTMED VSPGTSQMRA RRHKRETLKM TKYVELVIVA DNREFQRQGK DLEKVKQRLI
       250        260        270        280        290        300
EIANHVDKFY RPLNIRIVLV GVEVWNDIDK CSISQDPFTS LHEFLDWRKI KLLPRKSHDN
       310        320        330        340        350        360
AQLISGVYFQ GTTIGMAPIM SMCTAEQSGG VVMDHSDSPL GAAVTLAHEL GHNFGMNHDT
       370        380        390        400        410        420
LERGCSCRMA AEKGGCIMNP STGFPFPMVF SSCSRKDLEA SLEKGMGMCL FNLPEVKQAF
       430        440        450        460        470        480
GGRKCGNGYV EEGEECDCGE PEECTNRCCN ATTCTLKPDA VCAHGQCCED CQLKPPGTAC
       490        500        510        520        530        540
RGSSNSCDLP EFCTGTAPHC PANVYLHDGH PCQGVDGYCY NGICQTHEQQ CVTLWGPGAK
       550        560        570        580        590        600
PAPGICFERV NSAGDPYGNC GKDSKSAFAK CELRDAKCGK IQCQGGASRP VIGTNAVSIE
       610        620        630        640        650        660
TNIPQQEGGR ILCRGTHVYL GDDMPDPGLV LAGTKCAEGK ICLNRRCQNI SVFGVHKCAM
       670        680        690        700        710        720
QCHGRGVCNN RKNCHCEAHW APPFCDKFGF GGSTDSGPIR QADNQGLTVG ILVSILCLLA
       730        740        750        760        770        780
AGFVVYLKRK TLMRLLFTHK KTTMEKLRCV HPSRTPSGPH LGQAHHTPGK GLLMNRAPHF
       790        800        810        820        830        840
NTPKDRHSLK CQNMDISRPL DARAVPQLQS PQRVLLPLHQ TPRAPSGPAR PLPASPAVRQ
       850        860        870        880        890        900
AQGIRKPSPP QKPLPADPLS RTSRLTSALV RTPGQQEPGH RPAPIRPAPK HQVPRPSHNA

YIK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q61824-32-unknown	MSLWDQ...	32	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61824-32-unknown	MSLWDQ...	32	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123161
Q61824-32-unknown	MSLWDQ...	32	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120094
Q61824-206-unknown	ETLKMT...	206	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61824-206-unknown	ETLKMT...	206	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TSQMRA	199	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120094
...LVIVAD	220	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123161
...NAYIK	903	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)