TopFIND 4.0

Q61838: Pregnancy zone protein

General Information

Protein names
- Pregnancy zone protein
- Alpha-2-macroglobulin
- Alpha-2-M
- Alpha-2-macroglobulin 165 kDa subunit
- Alpha-2-macroglobulin 35 kDa subunit
Gene names A2m
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q61838

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRRNQLPTPA FLLLFLLLPR DATTATAKPQ YVVLVPSEVY SGVPEKACVS LNHVNETVML 
        70         80         90        100        110        120 
SLTLEYAMQQ TKLLTDQAVD KDSFYCSPFT ISGSPLPYTF ITVEIKGPTQ RFIKKKSIQI 
       130        140        150        160        170        180 
IKAESPVFVQ TDKPIYKPGQ IVKFRVVSVD ISFRPLNETF PVVYIETPKR NRIFQWQNIH 
       190        200        210        220        230        240 
LAGGLHQLSF PLSVEPALGI YKVVVQKDSG KKIEHSFEVK EYVLPKFEVI IKMQKTMAFL 
       250        260        270        280        290        300 
EEELPITACG VYTYGKPVPG LVTLRVCRKY SRYRSTCHNQ NSMSICEEFS QQADDKGCFR 
       310        320        330        340        350        360 
QVVKTKVFQL RQKGHDMKIE VEAKIKEEGT GIELTGIGSC EIANALSKLK FTKVNTNYRP 
       370        380        390        400        410        420 
GLPFSGQVLL VDEKGKPIPN KNITSVVSPL GYLSIFTTDE HGLANISIDT SNFTAPFLRV 
       430        440        450        460        470        480 
VVTYKQNHVC YDNWWLDEFH TQADHSATLV FSPSQSYIQL ELVFGTLACG QTQEIRIHYL 
       490        500        510        520        530        540 
LNEDIMKNEK DLTFYYLIKA RGSIFNLGSH VLSLEQGNMK GVFSLPIQVE PGMAPEAQLL 
       550        560        570        580        590        600 
IYAILPNEEL VADAQNFEIE KCFANKVNLS FPSAQSLPAS DTHLKVKAAP LSLCALTAVD 
       610        620        630        640        650        660 
QSVLLLKPEA KLSPQSIYNL LPGKTVQGAF FGVPVYKDHE NCISGEDITH NGIVYTPKHS 
       670        680        690        700        710        720 
LGDNDAHSIF QSVGINIFTN SKIHKPRFCQ EFQHYPAMGG VAPQALAVAA SGPGSSFRAM 
       730        740        750        760        770        780 
GVPMMGLDYS DEINQVVEVR ETVRKYFPET WIWDLVPLDV SGDGELAVKV PDTITEWKAS 
       790        800        810        820        830        840 
AFCLSGTTGL GLSSTISLQA FQPFFLELTL PYSVVRGEAF TLKATVLNYM SHCIQIRVDL 
       850        860        870        880        890        900 
EISPDFLAVP VGGHENSHCI CGNERKTVSW AVTPKSLGEV NFTATAEALQ SPELCGNKLT 
       910        920        930        940        950        960 
EVPALVHKDT VVKSVIVEPE GIEKEQTYNT LLCPQDTELQ DNWSLELPPN VVEGSARATH 
       970        980        990       1000       1010       1020 
SVLGDILGSA MQNLQNLLQM PYGCGEQNMV LFVPNIYVLN YLNETQQLTE AIKSKAINYL 
      1030       1040       1050       1060       1070       1080 
ISGYQRQLNY QHSDGSYSTF GNHGGGNTPG NTWLTAFVLK AFAQAQSHIF IEKTHITNAF 
      1090       1100       1110       1120       1130       1140 
NWLSMKQKEN GCFQQSGYLL NNAMKGGVDD EVTLSAYITI ALLEMPLPVT HSAVRNALFC 
      1150       1160       1170       1180       1190       1200 
LETAWASISQ SQESHVYTKA LLAYAFALAG NKAKRSELLE SLNKDAVKEE DSLHWQRPGD 
      1210       1220       1230       1240       1250       1260 
VQKVKALSFY QPRAPSAEVE MTAYVLLAYL TSESSRPTRD LSSSDLSTAS KIVKWISKQQ 
      1270       1280       1290       1300       1310       1320 
NSHGGFSSTQ DTVVALQALS KYGAATFTRS QKEVLVTIES SGTFSKTFHV NSGNRLLLQE 
      1330       1340       1350       1360       1370       1380 
VRLPDLPGNY VTKGSGSGCV YLQTSLKYNI LPVADGKAPF ALQVNTLPLN FDKAGDHRTF 
      1390       1400       1410       1420       1430       1440 
QIRINVSYTG ERPSSNMVIV DVKMVSGFIP MKPSVKKLQD QPNIQRTEVN TNHVLIYIEK 
      1450       1460       1470       1480       1490    
LTNQTLGFSF AVEQDIPVKN LKPAPIKVYD YYETDEFTVE EYSAPFSDGS EQGNA

Isoforms



Sequence View



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q61838-25-unknown ATAKPQ... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q61838-1240-unknown DLSSSD... 1240 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)