TopFIND 4.0

Q62205: Sodium channel protein type 9 subunit alpha {ECO:0000250|UniProtKB:Q15858}

General Information

Protein names
- Sodium channel protein type 9 subunit alpha {ECO:0000250|UniProtKB:Q15858}
- Peripheral sodium channel 1
- PN1 {ECO:0000250|UniProtKB:O08562}
- Sodium channel protein type IX subunit alpha
- Voltage-gated sodium channel subunit alpha Nav1.7
Gene names Scn9a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q62205

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAMLPPPGPQ SFVHFTKQSL ALIEQRISEE KAKGHKDEKK DDEEEGPKPS SDLEAGKQLP 
        70         80         90        100        110        120 
FIYGDIPPGM VSEPLEDLDP YYADKKTFIV LNKGKAIFRF NATPALYMLS PFSPLRRISI 
       130        140        150        160        170        180 
KILVHSLFSM LIMCTILTNC IFMTMSNPPD WTKNVEYTFT GIYTFESLIK ILARGFCVGE 
       190        200        210        220        230        240 
FTFLRDPWNW LDFVVIVFAY LTEFVNLGNV SALRTFRVLR ALKTISVIPG LKTIVGALIQ 
       250        260        270        280        290        300 
SVKKLSDVMI LTVFCLSVFA LIGLQLFMGN LKHKCFRKDL EQNETLESIM STAESEEELK 
       310        320        330        340        350        360 
RYFYYLEGSK DALLCGFSTD SGQCPEGYEC VTAGRNPDYG YTSFDTFGWA FLALFRLMTQ 
       370        380        390        400        410        420 
DYWENLYQQT LRAAGKTYMI FFVVVIFLGS FYLINLILAV VAMAYEEQNQ ANIEEAKQKE 
       430        440        450        460        470        480 
LEFQQMLDRL KKEQEEAEAI AAAAAEYTSL GRSRIMGLSE SSSETSRLSS KSAKERRNRR 
       490        500        510        520        530        540 
KKKKQKLSSG EEKGDDEKLS KSGSEESIRK KSFHLGVEGH HRAREKRLST PNQSPLSIRG 
       550        560        570        580        590        600 
SLFSARRSSR TSLFSFKGRG RDLGSETEFA DDEHSIFGDN ESRRGSLFVP HRPRERRSSN 
       610        620        630        640        650        660 
ISQASRSPPV LPVNGKMHSA VDCNGVVSLV DGPSALMLPN GQLLPEVIID KATSDDSGTT 
       670        680        690        700        710        720 
NQMRKKRLSS SYFLSEDMLN DPHLRQRAMS RASILTNTVE ELEESRQKCP PWWYRFAHTF 
       730        740        750        760        770        780 
LIWNCSPYWI KFKKFIYFIV MDPFVDLAIT ICIVLNTLFM AMEHHPMTDE FKNVLAVGNL 
       790        800        810        820        830        840 
VFTGIFAAEM VLKLIAMDPY EYFQVGWNIF DSLIVTLSLV ELFLADVEGL SVLRSFRLLR 
       850        860        870        880        890        900 
VFKLAKSWPT LNMLIKIIGN SVGALGNLTL VLAIIVFIFA VVGMQLFGKS YKECVCKINE 
       910        920        930        940        950        960 
NCKLPRWHMN DFFHSFLIVF RVLCGEWIET MWDCMEVAGQ TMCLIVYMMV MVIGNLVVLN 
       970        980        990       1000       1010       1020 
LFLALLLSSF SSDNLTAIEE DTDANNLQIA VARIKRGINY VKQTLREFIL KSFSKKPKGS 
      1030       1040       1050       1060       1070       1080 
KDTKRTADPN NKRENYISNR TLAEISKDHN FLKEKDKISG FSSSLDKSFM DENDYQSFIH 
      1090       1100       1110       1120       1130       1140 
NPSLTVTVPI APGESDLENM NTEELSSDSD SDYSKERRNR SSSSECSTVD NPLPGEEEAE 
      1150       1160       1170       1180       1190       1200 
AEPINADEPE ACFTDGCVRR FPCCQVNIDS GKGKVWWTIR KTCYRIVEHS WFESFIVLMI 
      1210       1220       1230       1240       1250       1260 
LLSSGALAFE DIYIEKKKTI KIILEYADKI FTYIFILEML LKWVAYGYKT YFTNAWCWLD 
      1270       1280       1290       1300       1310       1320 
FLIVDVSLVT LVANTLGYSD LGPIKSLRTL RALRPLRALS RFEGMRVVVN ALIGAIPSIM 
      1330       1340       1350       1360       1370       1380 
NVLLVCLIFW LIFSIMGVNL FAGKFYECVN TTDGSRFSVS QVANRSECFA LMNVSGNVRW 
      1390       1400       1410       1420       1430       1440 
KNLKVNFDNV GLGYLSLLQV ATFKGWMDIM YAAVDSVNVN AQPIYEYNLY MYIYFVIFII 
      1450       1460       1470       1480       1490       1500 
FGSFFTLNLF IGVIIDNFNQ QKKKLGGQDI FMTEEQKKYY NAMKKLGSKK PQKPIPRPGN 
      1510       1520       1530       1540       1550       1560 
KFQGCIFDLV TNQAFDITIM VLICLNMVTM MVEKEGQTDY MSFVLYWINV VFIILFTGEC 
      1570       1580       1590       1600       1610       1620 
VLKLISLRHY YFTVGWNIFD FVVVILSIVG MFLAEMIEKY FVSPTLFRVI RLARIGRILR 
      1630       1640       1650       1660       1670       1680 
LIKGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYAIFG MSNFAYVKKE AGINDMFNFE 
      1690       1700       1710       1720       1730       1740 
TFGNSMICLF QITTSAGWDG LLAPILNSAP PDCDPKKVHP GSSVEGDCGN PSVGIFYFVS 
      1750       1760       1770       1780       1790       1800 
YIIISFLVVV NMYIAVILEN FSVATEESTE PLSEDDFEMF YEVWEKFDPD ATQFIEFCKL 
      1810       1820       1830       1840       1850       1860 
SDFAAALDPP LLIAKPNKVQ LIAMDLPMVS GDRIHCLDIL FAFTKRVLGE SGEMDSLRSQ 
      1870       1880       1890       1900       1910       1920 
MEERFMSANP SKVSYEPITT TLKRKQEDVS ATIIQRAYRR YRLRQNVKNI SSIYIKDGDR 
      1930       1940       1950       1960       1970       1980 
DDDLPNKEDI VFDNVNENSS PEKTDATAST ISPPSYDSVT KPDQEKYETD KTEKEDKEKD 
   
ESRK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q62205-1-unknown MAMLPP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DESRK 1984 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)