Q62230: Sialoadhesin
| Protein names | - Sialoadhesin - Sheep erythrocyte receptor - SER - Sialic acid-binding Ig-like lectin 1 - Siglec-1 - CD169 |
|---|---|
| Gene names | Siglec1 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q62230 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MCVLFSLLLL ASVFSLGQTT WGVSSPKNVQ GLSGSCLLIP CIFSYPADVP VSNGITAIWY
70 80 90 100 110 120
YDYSGKRQVV IHSGDPKLVD KRFRGRAELM GNMDHKVCNL LLKDLKPEDS GTYNFRFEIS
130 140 150 160 170 180
DSNRWLDVKG TTVTVTTDPS PPTITIPEEL REGMERNFNC STPYLCLQEK QVSLQWRGQD
190 200 210 220 230 240
PTHSVTSSFQ SLEPTGVYHQ TTLHMALSWQ DHGRTLLCQF SLGAHSSRKE VYLQVPHAPK
250 260 270 280 290 300
GVEILLSSSG RNILPGDPVT LTCRVNSSYP AVSAVQWARD GVNLGVTGHV LRLFSAAWND
310 320 330 340 350 360
SGAYTCQATN DMGSLVSSPL SLHVFMAEVK MNPAGPVLEN ETVTLLCSTP KEAPQELRYS
370 380 390 400 410 420
WYKNHILLED AHASTLHLPA VTRADTGFYF CEVQNAQGSE RSSPLSVVVR YPPLTPDLTT
430 440 450 460 470 480
FLETQAGLVG ILHCSVVSEP LATVVLSHGG LTLASNSGEN DFNPRFRISS APNSLRLEIR
490 500 510 520 530 540
DLQPADSGEY TCLAVNSLGN STSSLDFYAN VARLLINPSA EVVEGQAVTL SCRSGLSPAP
550 560 570 580 590 600
DTRFSWYLNG ALLLEGSSSS LLLPAASSTD AGSYYCRTQA GPNTSGPSLP TVLTVFYPPR
610 620 630 640 650 660
KPTFTARLDL DTSGVGDGRR GILLCHVDSD PPAQLRLLHK GHVVATSLPS RCGSCSQRTK
670 680 690 700 710 720
VSRTSNSLHV EIQKPVLEDE GVYLCEASNT LGNSSAAASF NAKATVLVIT PSNTLREGTE
730 740 750 760 770 780
ANLTCNVNQE VAVSPANFSW FRNGVLWTQG SLETVRLQPV ARTDAAVYAC RLLTEDGAQL
790 800 810 820 830 840
SAPVVLSVLY APDPPKLSAL LDVGQGHMAV FICTVDSYPL AHLSLFRGDH LLATNLEPQR
850 860 870 880 890 900
PSHGRIQAKA TANSLQLEVR ELGLVDSGNY HCEATNILGS ANSSLFFQVR GAWVQVSPSP
910 920 930 940 950 960
ELREGQAVVL SCQVPTGVSE GTSYSWYQDG RPLQESTSST LRIAAISLRQ AGAYHCQAQA
970 980 990 1000 1010 1020
PDTAIASLAA PVSLHVSYTP RHVTLSALLS TDPERLGHLV CSVQSDPPAQ LQLFHRNRLV
1030 1040 1050 1060 1070 1080
ASTLQGADEL AGSNPRLHVT VLPNELRLQI HFPELEDDGT YTCEASNTLG QASAAADFDA
1090 1100 1110 1120 1130 1140
QAVRVTVWPN ATVQEGQQVN LTCLVWSTHQ DSLSYTWYKG GQQLLGARSI TLPSVKVLDA
1150 1160 1170 1180 1190 1200
TSYRCGVGLP GHAPHLSRPV TLDVLHAPRN LRLTYLLETQ GRQLALVLCT VDSRPPAQLT
1210 1220 1230 1240 1250 1260
LSHGDQLVAS STEASVPNTL RLELQDPRPS NEGLYSCSAH SPLGKANTSL ELLLEGVRVK
1270 1280 1290 1300 1310 1320
MNPSGSVPEG EPVTVTCEDP AALSSALYAW FHNGHWLQEG PASSLQFLVT TRAHAGAYFC
1330 1340 1350 1360 1370 1380
QVHDTQGTRS SRPASLQILY APRDAVLSSF RDSRTRLMVV IQCTVDSEPP AEMVLSHNGK
1390 1400 1410 1420 1430 1440
VLAASHERHS SASGIGHIQV ARNALRLQVQ DVTLGDGNTY VCTAQNTLGS ISTTQRLLTE
1450 1460 1470 1480 1490 1500
TDIRVTAEPG LDVPEGTALN LSCLLPGGSG PTGNSSFTWF WNRHRLHSAP VPTLSFTPVV
1510 1520 1530 1540 1550 1560
RAQAGLYHCR ADLPTGATTS APVMLRVLYP PKTPTLIVFV EPQGGHQGIL DCRVDSEPLA
1570 1580 1590 1600 1610 1620
ILTLHRGSQL VASNQLHDAP TKPHIRVTAP PNALRVDIEE LGPSNQGEYV CTASNTLGSA
1630 1640 1650 1660 1670 1680
SASAYFGTRA LHQLQLFQRL LWVLGFLAGF LCLLLGLVAY HTWRKKSSTK LNEDENSAEM
1690
ATKKNTIQEE VVAAL
Isoforms
- Isoform 2 of Sialoadhesin - Isoform 3 of SialoadhesinSequence View
10 20 30 40 50 60
MCVLFSLLLL ASVFSLGQTT WGVSSPKNVQ GLSGSCLLIP CIFSYPADVP VSNGITAIWY
70 80 90 100 110 120
YDYSGKRQVV IHSGDPKLVD KRFRGRAELM GNMDHKVCNL LLKDLKPEDS GTYNFRFEIS
130 140 150 160 170 180
DSNRWLDVKG TTVTVTTDPS PPTITIPEEL REGMERNFNC STPYLCLQEK QVSLQWRGQD
190 200 210 220 230 240
PTHSVTSSFQ SLEPTGVYHQ TTLHMALSWQ DHGRTLLCQF SLGAHSSRKE VYLQVPHAPK
250 260 270 280 290 300
GVEILLSSSG RNILPGDPVT LTCRVNSSYP AVSAVQWARD GVNLGVTGHV LRLFSAAWND
310 320 330 340 350 360
SGAYTCQATN DMGSLVSSPL SLHVFMAEVK MNPAGPVLEN ETVTLLCSTP KEAPQELRYS
370 380 390 400 410 420
WYKNHILLED AHASTLHLPA VTRADTGFYF CEVQNAQGSE RSSPLSVVVR YPPLTPDLTT
430 440 450 460 470 480
FLETQAGLVG ILHCSVVSEP LATVVLSHGG LTLASNSGEN DFNPRFRISS APNSLRLEIR
490 500 510 520 530 540
DLQPADSGEY TCLAVNSLGN STSSLDFYAN VARLLINPSA EVVEGQAVTL SCRSGLSPAP
550 560 570 580 590 600
DTRFSWYLNG ALLLEGSSSS LLLPAASSTD AGSYYCRTQA GPNTSGPSLP TVLTVFYPPR
610 620 630 640 650 660
KPTFTARLDL DTSGVGDGRR GILLCHVDSD PPAQLRLLHK GHVVATSLPS RCGSCSQRTK
670 680 690 700 710 720
VSRTSNSLHV EIQKPVLEDE GVYLCEASNT LGNSSAAASF NAKATVLVIT PSNTLREGTE
730 740 750 760 770 780
ANLTCNVNQE VAVSPANFSW FRNGVLWTQG SLETVRLQPV ARTDAAVYAC RLLTEDGAQL
790 800 810 820 830 840
SAPVVLSVLY APDPPKLSAL LDVGQGHMAV FICTVDSYPL AHLSLFRGDH LLATNLEPQR
850 860 870 880 890 900
PSHGRIQAKA TANSLQLEVR ELGLVDSGNY HCEATNILGS ANSSLFFQVR GAWVQVSPSP
910 920 930 940 950 960
ELREGQAVVL SCQVPTGVSE GTSYSWYQDG RPLQESTSST LRIAAISLRQ AGAYHCQAQA
970 980 990 1000 1010 1020
PDTAIASLAA PVSLHVSYTP RHVTLSALLS TDPERLGHLV CSVQSDPPAQ LQLFHRNRLV
1030 1040 1050 1060 1070 1080
ASTLQGADEL AGSNPRLHVT VLPNELRLQI HFPELEDDGT YTCEASNTLG QASAAADFDA
1090 1100 1110 1120 1130 1140
QAVRVTVWPN ATVQEGQQVN LTCLVWSTHQ DSLSYTWYKG GQQLLGARSI TLPSVKVLDA
1150 1160 1170 1180 1190 1200
TSYRCGVGLP GHAPHLSRPV TLDVLHAPRN LRLTYLLETQ GRQLALVLCT VDSRPPAQLT
1210 1220 1230 1240 1250 1260
LSHGDQLVAS STEASVPNTL RLELQDPRPS NEGLYSCSAH SPLGKANTSL ELLLEGVRVK
1270 1280 1290 1300 1310 1320
MNPSGSVPEG EPVTVTCEDP AALSSALYAW FHNGHWLQEG PASSLQFLVT TRAHAGAYFC
1330 1340 1350 1360 1370 1380
QVHDTQGTRS SRPASLQILY APRDAVLSSF RDSRTRLMVV IQCTVDSEPP AEMVLSHNGK
1390 1400 1410 1420 1430 1440
VLAASHERHS SASGIGHIQV ARNALRLQVQ DVTLGDGNTY VCTAQNTLGS ISTTQRLLTE
1450 1460 1470 1480 1490 1500
TDIRVTAEPG LDVPEGTALN LSCLLPGGSG PTGNSSFTWF WNRHRLHSAP VPTLSFTPVV
1510 1520 1530 1540 1550 1560
RAQAGLYHCR ADLPTGATTS APVMLRVLYP PKTPTLIVFV EPQGGHQGIL DCRVDSEPLA
1570 1580 1590 1600 1610 1620
ILTLHRGSQL VASNQLHDAP TKPHIRVTAP PNALRVDIEE LGPSNQGEYV CTASNTLGSA
1630 1640 1650 1660 1670 1680
SASAYFGTRA LHQLQLFQRL LWVLGFLAGF LCLLLGLVAY HTWRKKSSTK LNEDENSAEM
1690
ATKKNTIQEE VVAAL
10 20 30 40 50 60
MCVLFSLLLL ASVFSLGQTT WGVSSPKNVQ GLSGSCLLIP CIFSYPADVP VSNGITAIWY
70 80 90 100 110 120
YDYSGKRQVV IHSGDPKLVD KRFRGRAELM GNMDHKVCNL LLKDLKPEDS GTYNFRFEIS
130 140 150 160 170 180
DSNRWLDVKG TTVTVTTDPS PPTITIPEEL REGMERNFNC STPYLCLQEK QVSLQWRGQD
190 200 210 220 230 240
PTHSVTSSFQ SLEPTGVYHQ TTLHMALSWQ DHGRTLLCQF SLGAHSSRKE VYLQVPHAPK
250 260 270 280 290 300
GVEILLSSSG RNILPGDPVT LTCRVNSSYP AVSAVQWARD GVNLGVTGHV LRLFSAAWND
310 320 330 340 350 360
SGAYTCQATN DMGSLVSSPL SLHVFMAEVK MNPAGPVLEN ETVTLLCSTP KEAPQELRYS
370 380 390 400 410 420
WYKNHILLED AHASTLHLPA VTRADTGFYF CEVQNAQGSE RSSPLSVVVR YPPLTPDLTT
430 440 450 460 470 480
FLETQAGLVG ILHCSVVSEP LATVVLSHGG LTLASNSGEN DFNPRFRISS APNSLRLEIR
490 500 510 520 530 540
DLQPADSGEY TCLAVNSLGN STSSLDFYAN VARLLINPSA EVVEGQAVTL SCRSGLSPAP
550 560 570 580 590 600
DTRFSWYLNG ALLLEGSSSS LLLPAASSTD AGSYYCRTQA GPNTSGPSLP TVLTVFYPPR
610 620 630 640 650 660
KPTFTARLDL DTSGVGDGRR GILLCHVDSD PPAQLRLLHK GHVVATSLPS RCGSCSQRTK
670 680 690 700 710 720
VSRTSNSLHV EIQKPVLEDE GVYLCEASNT LGNSSAAASF NAKATVLVIT PSNTLREGTE
730 740 750 760 770 780
ANLTCNVNQE VAVSPANFSW FRNGVLWTQG SLETVRLQPV ARTDAAVYAC RLLTEDGAQL
790 800 810 820 830 840
SAPVVLSVLY APDPPKLSAL LDVGQGHMAV FICTVDSYPL AHLSLFRGDH LLATNLEPQR
850 860 870 880 890 900
PSHGRIQAKA TANSLQLEVR ELGLVDSGNY HCEATNILGS ANSSLFFQVR GAWVQVSPSP
910 920 930 940 950 960
ELREGQAVVL SCQVPTGVSE GTSYSWYQDG RPLQESTSST LRIAAISLRQ AGAYHCQAQA
970 980 990 1000 1010 1020
PDTAIASLAA PVSLHVSYTP RHVTLSALLS TDPERLGHLV CSVQSDPPAQ LQLFHRNRLV
1030 1040 1050 1060 1070 1080
ASTLQGADEL AGSNPRLHVT VLPNELRLQI HFPELEDDGT YTCEASNTLG QASAAADFDA
1090 1100 1110 1120 1130 1140
QAVRVTVWPN ATVQEGQQVN LTCLVWSTHQ DSLSYTWYKG GQQLLGARSI TLPSVKVLDA
1150 1160 1170 1180 1190 1200
TSYRCGVGLP GHAPHLSRPV TLDVLHAPRN LRLTYLLETQ GRQLALVLCT VDSRPPAQLT
1210 1220 1230 1240 1250 1260
LSHGDQLVAS STEASVPNTL RLELQDPRPS NEGLYSCSAH SPLGKANTSL ELLLEGVRVK
1270 1280 1290 1300 1310 1320
MNPSGSVPEG EPVTVTCEDP AALSSALYAW FHNGHWLQEG PASSLQFLVT TRAHAGAYFC
1330 1340 1350 1360 1370 1380
QVHDTQGTRS SRPASLQILY APRDAVLSSF RDSRTRLMVV IQCTVDSEPP AEMVLSHNGK
1390 1400 1410 1420 1430 1440
VLAASHERHS SASGIGHIQV ARNALRLQVQ DVTLGDGNTY VCTAQNTLGS ISTTQRLLTE
1450 1460 1470 1480 1490 1500
TDIRVTAEPG LDVPEGTALN LSCLLPGGSG PTGNSSFTWF WNRHRLHSAP VPTLSFTPVV
1510 1520 1530 1540 1550 1560
RAQAGLYHCR ADLPTGATTS APVMLRVLYP PKTPTLIVFV EPQGGHQGIL DCRVDSEPLA
1570 1580 1590 1600 1610 1620
ILTLHRGSQL VASNQLHDAP TKPHIRVTAP PNALRVDIEE LGPSNQGEYV CTASNTLGSA
1630 1640 1650 1660 1670 1680
SASAYFGTRA LHQLQLFQRL LWVLGFLAGF LCLLLGLVAY HTWRKKSSTK LNEDENSAEM
1690
ATKKNTIQEE VVAAL
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q62230-1-unknown | MCVLFS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90202 | |||
| Q62230-1-unknown | MCVLFS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90203 | |||
| Q62230-20-unknown | TWGVSS... | 20 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q62230-20-unknown | TWGVSS... | 20 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt112346 | |||
| Q62230-20-unknown | TWGVSS... | 20 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt112347 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...VVAAL | 1695 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|