Q62407: Striated muscle-specific serine/threonine-protein kinase
| Protein names | - Striated muscle-specific serine/threonine-protein kinase - 2.7.11.1 - Aortic preferentially expressed protein 1 - APEG-1 |
|---|---|
| Gene names | Speg |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q62407 |
2
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MQKARGTRGE DAGTRAPPSP GVPPKRAKVG AGRGVLVTGD GAGAPVFLRP LKNAAVCAGS
70 80 90 100 110 120
DVRLRVVVSG TPQPSLSWFR DGQLLPPPAP EPSCLWLRSC GAQDAGVYSC SAQNERGQAS
130 140 150 160 170 180
CEAVLTVLEV RDSETAEDDI SDVPGTQRLE LRDDRAFSTP TGGSDTLVGT SLDTPPTSVT
190 200 210 220 230 240
GTSEEQVSWW GSGQTVLEQE AGSGGGTRPL PGSPRQAQTT GAGPRHLGVE PLVRASRANL
250 260 270 280 290 300
VGASWGSEDS LSVASDLYGS AFSLYRGRAL SIHVSIPPSG LHREEPDLQP QPASDALRPR
310 320 330 340 350 360
PALPPPSKSA LLPPPSPRVG KRALPGPSTQ PPATPTSPHR RAQEPSLPED ITTTEEKRGK
370 380 390 400 410 420
KPKSSGPSLA GTVESRPQTP LSEASGRLSA LGRSPRLVRA GSRILDKLQF FEERRRSLER
430 440 450 460 470 480
SDSPPAPLRP WVPLRKARSL EQPKSEGGAA WGTPEASQEE LRSPRGSVAE RRRLFQQKAA
490 500 510 520 530 540
SLDERTRQRS ATSDLELRFA QELGRIRRST SREELVRSHE SLRATLQRAP SPREPGEPPL
550 560 570 580 590 600
FSRPSTPKTS RAVSPAATQP PPPSGAGKSG DEPGRPRSRG PVGRTEPGEG PQQEIKRRDQ
610 620 630 640 650 660
FPLTRSRAIQ ECRSPVPPYT ADPPESRTKA PSGRKREPPA QAVRFLPWAT PGVEDSVLPQ
670 680 690 700 710 720
TLEKNRAGPE AEKRLRRGPE EDGPWGPWDR RGTRSQGKGR RARPTSPELE SSDDSYVSAG
730 740 750 760 770 780
EEPLEAPVFE IPLQNMVVAP GADVLLKCII TANPPPQVSW KKDGSMLHSE GRLLIRAEGE
790 800 810 820 830 840
RHTLLLREAQ AADAGSYTAT ATNELGQATC ASSLAVRPGG STSPFSSPIT SDEEYLSPPE
850 860 870 880 890 900
EFPEPGETWP RTPTMKLSPS QDHDSSDSSS KAPPTFKVSL MDQSVREGQD VIMSIRVQGE
910 920 930 940 950 960
PKPVVSWLRN RQPVRPDQRR FAEEAEGGLC RLRILAAERG DAGFYTCKAV NEYGARQCEA
970 980 990 1000 1010 1020
RLEVRAHPES RSLAVLAPLQ DVDVGAGEMA LFECLVAGPA DVEVDWLCRG RLLQPALLKC
1030 1040 1050 1060 1070 1080
KMHFDGRKCK LLLTSVHEDD SGVYTCKLST AKDELTCSAR LTVRPSLAPL FTRLLEDVEV
1090 1100 1110 1120 1130 1140
LEGRAARLDC KISGTPPPSV TWTHFGHPVN EGDNLRLRQD GGLHSLHIAR VGSEDEGLYE
1150 1160 1170 1180 1190 1200
VSATNTHGQA HCSAQLYVEE PRTAASGPSS KLEKMPSIPE EPEHGDLERL SIPDFLRPLQ
1210 1220 1230 1240 1250 1260
DLEVGLAKEA MLECQVTGLP YPTISWFHNG HRIQSSDDRR MTQYRDIHRL VFPAVGPQHA
1270 1280 1290 1300 1310 1320
GVYKSVIANK LGKAACYAHL YVTDVVPGPP DGAPEVVAVT GRMVTLSWNP PRSLDMAIDP
1330 1340 1350 1360 1370 1380
DSLTYTVQHQ VLGSDQWTAL VTGLREPAWA ATGLKKGIQH IFRVLSSSGK SSSKPSAPSE
1390 1400 1410 1420 1430 1440
PVQLLEHGPP LEEAPAVLDK QDIVYVVEGQ PACVTVTFNH VEAQVVWRSC RGALLEARTG
1450 1460 1470 1480 1490 1500
VYELSQPDDD QYCLRICRVS RRDLGPLTCS ARNRHGTKAC SVTLELAEAP RFESIMEDVE
1510 1520 1530 1540 1550 1560
VGPGETARFA VVVEGKPLPD IMWYKDEVLL AESNHVSFVY EENECSLVLL SAGSQDGGVY
1570 1580 1590 1600 1610 1620
TCTARNLAGE VSCKAELSVL SAQTAMEVEG VGEDEEHRGR RLSDYYDIHQ EIGRGAFSYL
1630 1640 1650 1660 1670 1680
RRVVERSSGL EFAAKFIPSQ AKPKASARRE ARLLARLQHG CVLYFHEAFE RRRGLVIVTE
1690 1700 1710 1720 1730 1740
LCTEELLERM ARKPTVCESE TRTYMRQVLE GICYLHQSHV LHLDVKPENL LVWDGAGGEE
1750 1760 1770 1780 1790 1800
QVRICDFGNA QELTPGEPQY CQYGTPEFVA PEIVNQSPVS GVTDIWPVGV VAFLCLTGIS
1810 1820 1830 1840 1850 1860
PFVGENDRTT LMNIRNYNVA FEETTFLSLS REARGFLIKV LVQDRLRPTA EETLEHPWFK
1870 1880 1890 1900 1910 1920
TEAKGAEVST DHLKLFLSRR RWQRSQISYK CHLVLRPIPE LLRAPPERVW VAMPRRQPPS
1930 1940 1950 1960 1970 1980
GGLSSSSDSE EEELEELPSV PRPLQPEFSG SRVSLTDIPT EDEALGTPEA GAATPMDWQE
1990 2000 2010 2020 2030 2040
QERTPSKDQE APSPEALPSP GQESPDGPSP RRPELRRGSS AESALPRVGS REPGRSLHKA
2050 2060 2070 2080 2090 2100
ASVELPQRRS PSPGATRLTR GGLGEGEYAQ RLQALRQRLL RGGPEDGKVS GLRGPLLESL
2110 2120 2130 2140 2150 2160
GGRARDPRMA RAASSEAAPH HQPPPESRGL QKSSSFSQGE AEPRGRHRRA GAPLEIPVAR
2170 2180 2190 2200 2210 2220
LGARRLQESP SLSALSETQP PSPARPSVPK LSITKSPEPS AVTSRDSPQP PEPQPVPEKV
2230 2240 2250 2260 2270 2280
PEPKPEPVRA AKPAQPPLAL QMPTQPLTPY AQIMQSLQLS SPTLSPQDPA VPPSEPKPHA
2290 2300 2310 2320 2330 2340
AVFARVASPP PGVSEKRVPS ARTPPVLAEK ARVPTVPPRP GSSLSGSIEN LESEAVFEAK
2350 2360 2370 2380 2390 2400
FKRSRESPLS RGLRLLSRSR SEERGPFRGA EDDGIYRPSP AGTPLELVRR PERSRSVQDL
2410 2420 2430 2440 2450 2460
RVAGEPGLVR RLSLSLSQKL RRTPPGQRHP AWESRSGDGE SSEGGSSARA SPVLAVRRRL
2470 2480 2490 2500 2510 2520
SSTLERLSSR LQRSGSSEDS GGASGRSTPL FGRLRRATSE GESLRRLGVP HNQLGSQTGA
2530 2540 2550 2560 2570 2580
TTPSAESLGS EASGTSGSSA PGESRSRHRW GLSRLRKDKG LSQPNLSSSV QEDLGHQYVP
2590 2600 2610 2620 2630 2640
SESDFPPVFH IKLKDQVLLE GEAATLLCLP AACPAPRISW MKDKQSLRSE PSVVIVSCKD
2650 2660 2670 2680 2690 2700
GRQLLSIPRA GKRHAGLYEC SATNVLGSIT SSCTVAVARI PGKLAPPEVP QTYHDTALVV
2710 2720 2730 2740 2750 2760
WKPGDGRAPC TYTLERRVDG ESVWHPVSSG IPDCYYNVTQ LPVGVTVRFR VACSNRAGQG
2770 2780 2790 2800 2810 2820
PFSNPSEKVF IRGTPDSPAQ PAAAPRDAPV TSGPTRAPPP DSPTSLAPTP ALAPPASQAS
2830 2840 2850 2860 2870 2880
TLSPSTSSMS ANQALSSLKA VGPPPATPPR KHRGLLATQQ AEPSPPSIVV TPSEPRSFVP
2890 2900 2910 2920 2930 2940
DTGTLTPTSS PQGVKPAPSS TSLYMVTSFV SAPPAPQAPA PEPPPEPTKV TVRSLSPAKE
2950 2960 2970 2980 2990 3000
VVSSPTPEST TLRQGPPQKP YTFLEEKARG RFGVVRSCRE NATGRTFVAK IVPYAAEGKR
3010 3020 3030 3040 3050 3060
RVLQEYEVLR TLHHERLMSL HEAYITPRYL VLIAESCGNR ELLCGLSDRF RYSEDDVATY
3070 3080 3090 3100 3110 3120
VVQLLQGLDY LHGHHVLHLD IKPDNLLLAA DNALKIVDFG SAQPYNPQAL KPLGHRTGTL
3130 3140 3150 3160 3170 3180
EFMAPEMVKG DPIGSATDIW GAGVLTYIML SGYSPFYEPD PQETEARIVG GRFDAFQLYP
3190 3200 3210 3220 3230 3240
NTSQSATLFL RKVLSVHPWS RPSLQDCLAH PWLQDAYLMK LRRQTLTFTT NRLKEFLGEQ
3250 3260
RRRRAEAATR HKVLLRSYPG SP
Isoforms
- Isoform 2 of Striated muscle-specific serine/threonine-protein kinase - Isoform 3 of Striated muscle-specific serine/threonine-protein kinase - Isoform 4 of Striated muscle-specific serine/threonine-protein kinaseSequence View
10 20 30 40 50 60
MQKARGTRGE DAGTRAPPSP GVPPKRAKVG AGRGVLVTGD GAGAPVFLRP LKNAAVCAGS
70 80 90 100 110 120
DVRLRVVVSG TPQPSLSWFR DGQLLPPPAP EPSCLWLRSC GAQDAGVYSC SAQNERGQAS
130 140 150 160 170 180
CEAVLTVLEV RDSETAEDDI SDVPGTQRLE LRDDRAFSTP TGGSDTLVGT SLDTPPTSVT
190 200 210 220 230 240
GTSEEQVSWW GSGQTVLEQE AGSGGGTRPL PGSPRQAQTT GAGPRHLGVE PLVRASRANL
250 260 270 280 290 300
VGASWGSEDS LSVASDLYGS AFSLYRGRAL SIHVSIPPSG LHREEPDLQP QPASDALRPR
310 320 330 340 350 360
PALPPPSKSA LLPPPSPRVG KRALPGPSTQ PPATPTSPHR RAQEPSLPED ITTTEEKRGK
370 380 390 400 410 420
KPKSSGPSLA GTVESRPQTP LSEASGRLSA LGRSPRLVRA GSRILDKLQF FEERRRSLER
430 440 450 460 470 480
SDSPPAPLRP WVPLRKARSL EQPKSEGGAA WGTPEASQEE LRSPRGSVAE RRRLFQQKAA
490 500 510 520 530 540
SLDERTRQRS ATSDLELRFA QELGRIRRST SREELVRSHE SLRATLQRAP SPREPGEPPL
550 560 570 580 590 600
FSRPSTPKTS RAVSPAATQP PPPSGAGKSG DEPGRPRSRG PVGRTEPGEG PQQEIKRRDQ
610 620 630 640 650 660
FPLTRSRAIQ ECRSPVPPYT ADPPESRTKA PSGRKREPPA QAVRFLPWAT PGVEDSVLPQ
670 680 690 700 710 720
TLEKNRAGPE AEKRLRRGPE EDGPWGPWDR RGTRSQGKGR RARPTSPELE SSDDSYVSAG
730 740 750 760 770 780
EEPLEAPVFE IPLQNMVVAP GADVLLKCII TANPPPQVSW KKDGSMLHSE GRLLIRAEGE
790 800 810 820 830 840
RHTLLLREAQ AADAGSYTAT ATNELGQATC ASSLAVRPGG STSPFSSPIT SDEEYLSPPE
850 860 870 880 890 900
EFPEPGETWP RTPTMKLSPS QDHDSSDSSS KAPPTFKVSL MDQSVREGQD VIMSIRVQGE
910 920 930 940 950 960
PKPVVSWLRN RQPVRPDQRR FAEEAEGGLC RLRILAAERG DAGFYTCKAV NEYGARQCEA
970 980 990 1000 1010 1020
RLEVRAHPES RSLAVLAPLQ DVDVGAGEMA LFECLVAGPA DVEVDWLCRG RLLQPALLKC
1030 1040 1050 1060 1070 1080
KMHFDGRKCK LLLTSVHEDD SGVYTCKLST AKDELTCSAR LTVRPSLAPL FTRLLEDVEV
1090 1100 1110 1120 1130 1140
LEGRAARLDC KISGTPPPSV TWTHFGHPVN EGDNLRLRQD GGLHSLHIAR VGSEDEGLYE
1150 1160 1170 1180 1190 1200
VSATNTHGQA HCSAQLYVEE PRTAASGPSS KLEKMPSIPE EPEHGDLERL SIPDFLRPLQ
1210 1220 1230 1240 1250 1260
DLEVGLAKEA MLECQVTGLP YPTISWFHNG HRIQSSDDRR MTQYRDIHRL VFPAVGPQHA
1270 1280 1290 1300 1310 1320
GVYKSVIANK LGKAACYAHL YVTDVVPGPP DGAPEVVAVT GRMVTLSWNP PRSLDMAIDP
1330 1340 1350 1360 1370 1380
DSLTYTVQHQ VLGSDQWTAL VTGLREPAWA ATGLKKGIQH IFRVLSSSGK SSSKPSAPSE
1390 1400 1410 1420 1430 1440
PVQLLEHGPP LEEAPAVLDK QDIVYVVEGQ PACVTVTFNH VEAQVVWRSC RGALLEARTG
1450 1460 1470 1480 1490 1500
VYELSQPDDD QYCLRICRVS RRDLGPLTCS ARNRHGTKAC SVTLELAEAP RFESIMEDVE
1510 1520 1530 1540 1550 1560
VGPGETARFA VVVEGKPLPD IMWYKDEVLL AESNHVSFVY EENECSLVLL SAGSQDGGVY
1570 1580 1590 1600 1610 1620
TCTARNLAGE VSCKAELSVL SAQTAMEVEG VGEDEEHRGR RLSDYYDIHQ EIGRGAFSYL
1630 1640 1650 1660 1670 1680
RRVVERSSGL EFAAKFIPSQ AKPKASARRE ARLLARLQHG CVLYFHEAFE RRRGLVIVTE
1690 1700 1710 1720 1730 1740
LCTEELLERM ARKPTVCESE TRTYMRQVLE GICYLHQSHV LHLDVKPENL LVWDGAGGEE
1750 1760 1770 1780 1790 1800
QVRICDFGNA QELTPGEPQY CQYGTPEFVA PEIVNQSPVS GVTDIWPVGV VAFLCLTGIS
1810 1820 1830 1840 1850 1860
PFVGENDRTT LMNIRNYNVA FEETTFLSLS REARGFLIKV LVQDRLRPTA EETLEHPWFK
1870 1880 1890 1900 1910 1920
TEAKGAEVST DHLKLFLSRR RWQRSQISYK CHLVLRPIPE LLRAPPERVW VAMPRRQPPS
1930 1940 1950 1960 1970 1980
GGLSSSSDSE EEELEELPSV PRPLQPEFSG SRVSLTDIPT EDEALGTPEA GAATPMDWQE
1990 2000 2010 2020 2030 2040
QERTPSKDQE APSPEALPSP GQESPDGPSP RRPELRRGSS AESALPRVGS REPGRSLHKA
2050 2060 2070 2080 2090 2100
ASVELPQRRS PSPGATRLTR GGLGEGEYAQ RLQALRQRLL RGGPEDGKVS GLRGPLLESL
2110 2120 2130 2140 2150 2160
GGRARDPRMA RAASSEAAPH HQPPPESRGL QKSSSFSQGE AEPRGRHRRA GAPLEIPVAR
2170 2180 2190 2200 2210 2220
LGARRLQESP SLSALSETQP PSPARPSVPK LSITKSPEPS AVTSRDSPQP PEPQPVPEKV
2230 2240 2250 2260 2270 2280
PEPKPEPVRA AKPAQPPLAL QMPTQPLTPY AQIMQSLQLS SPTLSPQDPA VPPSEPKPHA
2290 2300 2310 2320 2330 2340
AVFARVASPP PGVSEKRVPS ARTPPVLAEK ARVPTVPPRP GSSLSGSIEN LESEAVFEAK
2350 2360 2370 2380 2390 2400
FKRSRESPLS RGLRLLSRSR SEERGPFRGA EDDGIYRPSP AGTPLELVRR PERSRSVQDL
2410 2420 2430 2440 2450 2460
RVAGEPGLVR RLSLSLSQKL RRTPPGQRHP AWESRSGDGE SSEGGSSARA SPVLAVRRRL
2470 2480 2490 2500 2510 2520
SSTLERLSSR LQRSGSSEDS GGASGRSTPL FGRLRRATSE GESLRRLGVP HNQLGSQTGA
2530 2540 2550 2560 2570 2580
TTPSAESLGS EASGTSGSSA PGESRSRHRW GLSRLRKDKG LSQPNLSSSV QEDLGHQYVP
2590 2600 2610 2620 2630 2640
SESDFPPVFH IKLKDQVLLE GEAATLLCLP AACPAPRISW MKDKQSLRSE PSVVIVSCKD
2650 2660 2670 2680 2690 2700
GRQLLSIPRA GKRHAGLYEC SATNVLGSIT SSCTVAVARI PGKLAPPEVP QTYHDTALVV
2710 2720 2730 2740 2750 2760
WKPGDGRAPC TYTLERRVDG ESVWHPVSSG IPDCYYNVTQ LPVGVTVRFR VACSNRAGQG
2770 2780 2790 2800 2810 2820
PFSNPSEKVF IRGTPDSPAQ PAAAPRDAPV TSGPTRAPPP DSPTSLAPTP ALAPPASQAS
2830 2840 2850 2860 2870 2880
TLSPSTSSMS ANQALSSLKA VGPPPATPPR KHRGLLATQQ AEPSPPSIVV TPSEPRSFVP
2890 2900 2910 2920 2930 2940
DTGTLTPTSS PQGVKPAPSS TSLYMVTSFV SAPPAPQAPA PEPPPEPTKV TVRSLSPAKE
2950 2960 2970 2980 2990 3000
VVSSPTPEST TLRQGPPQKP YTFLEEKARG RFGVVRSCRE NATGRTFVAK IVPYAAEGKR
3010 3020 3030 3040 3050 3060
RVLQEYEVLR TLHHERLMSL HEAYITPRYL VLIAESCGNR ELLCGLSDRF RYSEDDVATY
3070 3080 3090 3100 3110 3120
VVQLLQGLDY LHGHHVLHLD IKPDNLLLAA DNALKIVDFG SAQPYNPQAL KPLGHRTGTL
3130 3140 3150 3160 3170 3180
EFMAPEMVKG DPIGSATDIW GAGVLTYIML SGYSPFYEPD PQETEARIVG GRFDAFQLYP
3190 3200 3210 3220 3230 3240
NTSQSATLFL RKVLSVHPWS RPSLQDCLAH PWLQDAYLMK LRRQTLTFTT NRLKEFLGEQ
3250 3260
RRRRAEAATR HKVLLRSYPG SP
10 20 30 40 50 60
MQKARGTRGE DAGTRAPPSP GVPPKRAKVG AGRGVLVTGD GAGAPVFLRP LKNAAVCAGS
70 80 90 100 110 120
DVRLRVVVSG TPQPSLSWFR DGQLLPPPAP EPSCLWLRSC GAQDAGVYSC SAQNERGQAS
130 140 150 160 170 180
CEAVLTVLEV RDSETAEDDI SDVPGTQRLE LRDDRAFSTP TGGSDTLVGT SLDTPPTSVT
190 200 210 220 230 240
GTSEEQVSWW GSGQTVLEQE AGSGGGTRPL PGSPRQAQTT GAGPRHLGVE PLVRASRANL
250 260 270 280 290 300
VGASWGSEDS LSVASDLYGS AFSLYRGRAL SIHVSIPPSG LHREEPDLQP QPASDALRPR
310 320 330 340 350 360
PALPPPSKSA LLPPPSPRVG KRALPGPSTQ PPATPTSPHR RAQEPSLPED ITTTEEKRGK
370 380 390 400 410 420
KPKSSGPSLA GTVESRPQTP LSEASGRLSA LGRSPRLVRA GSRILDKLQF FEERRRSLER
430 440 450 460 470 480
SDSPPAPLRP WVPLRKARSL EQPKSEGGAA WGTPEASQEE LRSPRGSVAE RRRLFQQKAA
490 500 510 520 530 540
SLDERTRQRS ATSDLELRFA QELGRIRRST SREELVRSHE SLRATLQRAP SPREPGEPPL
550 560 570 580 590 600
FSRPSTPKTS RAVSPAATQP PPPSGAGKSG DEPGRPRSRG PVGRTEPGEG PQQEIKRRDQ
610 620 630 640 650 660
FPLTRSRAIQ ECRSPVPPYT ADPPESRTKA PSGRKREPPA QAVRFLPWAT PGVEDSVLPQ
670 680 690 700 710 720
TLEKNRAGPE AEKRLRRGPE EDGPWGPWDR RGTRSQGKGR RARPTSPELE SSDDSYVSAG
730 740 750 760 770 780
EEPLEAPVFE IPLQNMVVAP GADVLLKCII TANPPPQVSW KKDGSMLHSE GRLLIRAEGE
790 800 810 820 830 840
RHTLLLREAQ AADAGSYTAT ATNELGQATC ASSLAVRPGG STSPFSSPIT SDEEYLSPPE
850 860 870 880 890 900
EFPEPGETWP RTPTMKLSPS QDHDSSDSSS KAPPTFKVSL MDQSVREGQD VIMSIRVQGE
910 920 930 940 950 960
PKPVVSWLRN RQPVRPDQRR FAEEAEGGLC RLRILAAERG DAGFYTCKAV NEYGARQCEA
970 980 990 1000 1010 1020
RLEVRAHPES RSLAVLAPLQ DVDVGAGEMA LFECLVAGPA DVEVDWLCRG RLLQPALLKC
1030 1040 1050 1060 1070 1080
KMHFDGRKCK LLLTSVHEDD SGVYTCKLST AKDELTCSAR LTVRPSLAPL FTRLLEDVEV
1090 1100 1110 1120 1130 1140
LEGRAARLDC KISGTPPPSV TWTHFGHPVN EGDNLRLRQD GGLHSLHIAR VGSEDEGLYE
1150 1160 1170 1180 1190 1200
VSATNTHGQA HCSAQLYVEE PRTAASGPSS KLEKMPSIPE EPEHGDLERL SIPDFLRPLQ
1210 1220 1230 1240 1250 1260
DLEVGLAKEA MLECQVTGLP YPTISWFHNG HRIQSSDDRR MTQYRDIHRL VFPAVGPQHA
1270 1280 1290 1300 1310 1320
GVYKSVIANK LGKAACYAHL YVTDVVPGPP DGAPEVVAVT GRMVTLSWNP PRSLDMAIDP
1330 1340 1350 1360 1370 1380
DSLTYTVQHQ VLGSDQWTAL VTGLREPAWA ATGLKKGIQH IFRVLSSSGK SSSKPSAPSE
1390 1400 1410 1420 1430 1440
PVQLLEHGPP LEEAPAVLDK QDIVYVVEGQ PACVTVTFNH VEAQVVWRSC RGALLEARTG
1450 1460 1470 1480 1490 1500
VYELSQPDDD QYCLRICRVS RRDLGPLTCS ARNRHGTKAC SVTLELAEAP RFESIMEDVE
1510 1520 1530 1540 1550 1560
VGPGETARFA VVVEGKPLPD IMWYKDEVLL AESNHVSFVY EENECSLVLL SAGSQDGGVY
1570 1580 1590 1600 1610 1620
TCTARNLAGE VSCKAELSVL SAQTAMEVEG VGEDEEHRGR RLSDYYDIHQ EIGRGAFSYL
1630 1640 1650 1660 1670 1680
RRVVERSSGL EFAAKFIPSQ AKPKASARRE ARLLARLQHG CVLYFHEAFE RRRGLVIVTE
1690 1700 1710 1720 1730 1740
LCTEELLERM ARKPTVCESE TRTYMRQVLE GICYLHQSHV LHLDVKPENL LVWDGAGGEE
1750 1760 1770 1780 1790 1800
QVRICDFGNA QELTPGEPQY CQYGTPEFVA PEIVNQSPVS GVTDIWPVGV VAFLCLTGIS
1810 1820 1830 1840 1850 1860
PFVGENDRTT LMNIRNYNVA FEETTFLSLS REARGFLIKV LVQDRLRPTA EETLEHPWFK
1870 1880 1890 1900 1910 1920
TEAKGAEVST DHLKLFLSRR RWQRSQISYK CHLVLRPIPE LLRAPPERVW VAMPRRQPPS
1930 1940 1950 1960 1970 1980
GGLSSSSDSE EEELEELPSV PRPLQPEFSG SRVSLTDIPT EDEALGTPEA GAATPMDWQE
1990 2000 2010 2020 2030 2040
QERTPSKDQE APSPEALPSP GQESPDGPSP RRPELRRGSS AESALPRVGS REPGRSLHKA
2050 2060 2070 2080 2090 2100
ASVELPQRRS PSPGATRLTR GGLGEGEYAQ RLQALRQRLL RGGPEDGKVS GLRGPLLESL
2110 2120 2130 2140 2150 2160
GGRARDPRMA RAASSEAAPH HQPPPESRGL QKSSSFSQGE AEPRGRHRRA GAPLEIPVAR
2170 2180 2190 2200 2210 2220
LGARRLQESP SLSALSETQP PSPARPSVPK LSITKSPEPS AVTSRDSPQP PEPQPVPEKV
2230 2240 2250 2260 2270 2280
PEPKPEPVRA AKPAQPPLAL QMPTQPLTPY AQIMQSLQLS SPTLSPQDPA VPPSEPKPHA
2290 2300 2310 2320 2330 2340
AVFARVASPP PGVSEKRVPS ARTPPVLAEK ARVPTVPPRP GSSLSGSIEN LESEAVFEAK
2350 2360 2370 2380 2390 2400
FKRSRESPLS RGLRLLSRSR SEERGPFRGA EDDGIYRPSP AGTPLELVRR PERSRSVQDL
2410 2420 2430 2440 2450 2460
RVAGEPGLVR RLSLSLSQKL RRTPPGQRHP AWESRSGDGE SSEGGSSARA SPVLAVRRRL
2470 2480 2490 2500 2510 2520
SSTLERLSSR LQRSGSSEDS GGASGRSTPL FGRLRRATSE GESLRRLGVP HNQLGSQTGA
2530 2540 2550 2560 2570 2580
TTPSAESLGS EASGTSGSSA PGESRSRHRW GLSRLRKDKG LSQPNLSSSV QEDLGHQYVP
2590 2600 2610 2620 2630 2640
SESDFPPVFH IKLKDQVLLE GEAATLLCLP AACPAPRISW MKDKQSLRSE PSVVIVSCKD
2650 2660 2670 2680 2690 2700
GRQLLSIPRA GKRHAGLYEC SATNVLGSIT SSCTVAVARI PGKLAPPEVP QTYHDTALVV
2710 2720 2730 2740 2750 2760
WKPGDGRAPC TYTLERRVDG ESVWHPVSSG IPDCYYNVTQ LPVGVTVRFR VACSNRAGQG
2770 2780 2790 2800 2810 2820
PFSNPSEKVF IRGTPDSPAQ PAAAPRDAPV TSGPTRAPPP DSPTSLAPTP ALAPPASQAS
2830 2840 2850 2860 2870 2880
TLSPSTSSMS ANQALSSLKA VGPPPATPPR KHRGLLATQQ AEPSPPSIVV TPSEPRSFVP
2890 2900 2910 2920 2930 2940
DTGTLTPTSS PQGVKPAPSS TSLYMVTSFV SAPPAPQAPA PEPPPEPTKV TVRSLSPAKE
2950 2960 2970 2980 2990 3000
VVSSPTPEST TLRQGPPQKP YTFLEEKARG RFGVVRSCRE NATGRTFVAK IVPYAAEGKR
3010 3020 3030 3040 3050 3060
RVLQEYEVLR TLHHERLMSL HEAYITPRYL VLIAESCGNR ELLCGLSDRF RYSEDDVATY
3070 3080 3090 3100 3110 3120
VVQLLQGLDY LHGHHVLHLD IKPDNLLLAA DNALKIVDFG SAQPYNPQAL KPLGHRTGTL
3130 3140 3150 3160 3170 3180
EFMAPEMVKG DPIGSATDIW GAGVLTYIML SGYSPFYEPD PQETEARIVG GRFDAFQLYP
3190 3200 3210 3220 3230 3240
NTSQSATLFL RKVLSVHPWS RPSLQDCLAH PWLQDAYLMK LRRQTLTFTT NRLKEFLGEQ
3250 3260
RRRRAEAATR HKVLLRSYPG SP
10 20 30 40 50 60
MQKARGTRGE DAGTRAPPSP GVPPKRAKVG AGRGVLVTGD GAGAPVFLRP LKNAAVCAGS
70 80 90 100 110 120
DVRLRVVVSG TPQPSLSWFR DGQLLPPPAP EPSCLWLRSC GAQDAGVYSC SAQNERGQAS
130 140 150 160 170 180
CEAVLTVLEV RDSETAEDDI SDVPGTQRLE LRDDRAFSTP TGGSDTLVGT SLDTPPTSVT
190 200 210 220 230 240
GTSEEQVSWW GSGQTVLEQE AGSGGGTRPL PGSPRQAQTT GAGPRHLGVE PLVRASRANL
250 260 270 280 290 300
VGASWGSEDS LSVASDLYGS AFSLYRGRAL SIHVSIPPSG LHREEPDLQP QPASDALRPR
310 320 330 340 350 360
PALPPPSKSA LLPPPSPRVG KRALPGPSTQ PPATPTSPHR RAQEPSLPED ITTTEEKRGK
370 380 390 400 410 420
KPKSSGPSLA GTVESRPQTP LSEASGRLSA LGRSPRLVRA GSRILDKLQF FEERRRSLER
430 440 450 460 470 480
SDSPPAPLRP WVPLRKARSL EQPKSEGGAA WGTPEASQEE LRSPRGSVAE RRRLFQQKAA
490 500 510 520 530 540
SLDERTRQRS ATSDLELRFA QELGRIRRST SREELVRSHE SLRATLQRAP SPREPGEPPL
550 560 570 580 590 600
FSRPSTPKTS RAVSPAATQP PPPSGAGKSG DEPGRPRSRG PVGRTEPGEG PQQEIKRRDQ
610 620 630 640 650 660
FPLTRSRAIQ ECRSPVPPYT ADPPESRTKA PSGRKREPPA QAVRFLPWAT PGVEDSVLPQ
670 680 690 700 710 720
TLEKNRAGPE AEKRLRRGPE EDGPWGPWDR RGTRSQGKGR RARPTSPELE SSDDSYVSAG
730 740 750 760 770 780
EEPLEAPVFE IPLQNMVVAP GADVLLKCII TANPPPQVSW KKDGSMLHSE GRLLIRAEGE
790 800 810 820 830 840
RHTLLLREAQ AADAGSYTAT ATNELGQATC ASSLAVRPGG STSPFSSPIT SDEEYLSPPE
850 860 870 880 890 900
EFPEPGETWP RTPTMKLSPS QDHDSSDSSS KAPPTFKVSL MDQSVREGQD VIMSIRVQGE
910 920 930 940 950 960
PKPVVSWLRN RQPVRPDQRR FAEEAEGGLC RLRILAAERG DAGFYTCKAV NEYGARQCEA
970 980 990 1000 1010 1020
RLEVRAHPES RSLAVLAPLQ DVDVGAGEMA LFECLVAGPA DVEVDWLCRG RLLQPALLKC
1030 1040 1050 1060 1070 1080
KMHFDGRKCK LLLTSVHEDD SGVYTCKLST AKDELTCSAR LTVRPSLAPL FTRLLEDVEV
1090 1100 1110 1120 1130 1140
LEGRAARLDC KISGTPPPSV TWTHFGHPVN EGDNLRLRQD GGLHSLHIAR VGSEDEGLYE
1150 1160 1170 1180 1190 1200
VSATNTHGQA HCSAQLYVEE PRTAASGPSS KLEKMPSIPE EPEHGDLERL SIPDFLRPLQ
1210 1220 1230 1240 1250 1260
DLEVGLAKEA MLECQVTGLP YPTISWFHNG HRIQSSDDRR MTQYRDIHRL VFPAVGPQHA
1270 1280 1290 1300 1310 1320
GVYKSVIANK LGKAACYAHL YVTDVVPGPP DGAPEVVAVT GRMVTLSWNP PRSLDMAIDP
1330 1340 1350 1360 1370 1380
DSLTYTVQHQ VLGSDQWTAL VTGLREPAWA ATGLKKGIQH IFRVLSSSGK SSSKPSAPSE
1390 1400 1410 1420 1430 1440
PVQLLEHGPP LEEAPAVLDK QDIVYVVEGQ PACVTVTFNH VEAQVVWRSC RGALLEARTG
1450 1460 1470 1480 1490 1500
VYELSQPDDD QYCLRICRVS RRDLGPLTCS ARNRHGTKAC SVTLELAEAP RFESIMEDVE
1510 1520 1530 1540 1550 1560
VGPGETARFA VVVEGKPLPD IMWYKDEVLL AESNHVSFVY EENECSLVLL SAGSQDGGVY
1570 1580 1590 1600 1610 1620
TCTARNLAGE VSCKAELSVL SAQTAMEVEG VGEDEEHRGR RLSDYYDIHQ EIGRGAFSYL
1630 1640 1650 1660 1670 1680
RRVVERSSGL EFAAKFIPSQ AKPKASARRE ARLLARLQHG CVLYFHEAFE RRRGLVIVTE
1690 1700 1710 1720 1730 1740
LCTEELLERM ARKPTVCESE TRTYMRQVLE GICYLHQSHV LHLDVKPENL LVWDGAGGEE
1750 1760 1770 1780 1790 1800
QVRICDFGNA QELTPGEPQY CQYGTPEFVA PEIVNQSPVS GVTDIWPVGV VAFLCLTGIS
1810 1820 1830 1840 1850 1860
PFVGENDRTT LMNIRNYNVA FEETTFLSLS REARGFLIKV LVQDRLRPTA EETLEHPWFK
1870 1880 1890 1900 1910 1920
TEAKGAEVST DHLKLFLSRR RWQRSQISYK CHLVLRPIPE LLRAPPERVW VAMPRRQPPS
1930 1940 1950 1960 1970 1980
GGLSSSSDSE EEELEELPSV PRPLQPEFSG SRVSLTDIPT EDEALGTPEA GAATPMDWQE
1990 2000 2010 2020 2030 2040
QERTPSKDQE APSPEALPSP GQESPDGPSP RRPELRRGSS AESALPRVGS REPGRSLHKA
2050 2060 2070 2080 2090 2100
ASVELPQRRS PSPGATRLTR GGLGEGEYAQ RLQALRQRLL RGGPEDGKVS GLRGPLLESL
2110 2120 2130 2140 2150 2160
GGRARDPRMA RAASSEAAPH HQPPPESRGL QKSSSFSQGE AEPRGRHRRA GAPLEIPVAR
2170 2180 2190 2200 2210 2220
LGARRLQESP SLSALSETQP PSPARPSVPK LSITKSPEPS AVTSRDSPQP PEPQPVPEKV
2230 2240 2250 2260 2270 2280
PEPKPEPVRA AKPAQPPLAL QMPTQPLTPY AQIMQSLQLS SPTLSPQDPA VPPSEPKPHA
2290 2300 2310 2320 2330 2340
AVFARVASPP PGVSEKRVPS ARTPPVLAEK ARVPTVPPRP GSSLSGSIEN LESEAVFEAK
2350 2360 2370 2380 2390 2400
FKRSRESPLS RGLRLLSRSR SEERGPFRGA EDDGIYRPSP AGTPLELVRR PERSRSVQDL
2410 2420 2430 2440 2450 2460
RVAGEPGLVR RLSLSLSQKL RRTPPGQRHP AWESRSGDGE SSEGGSSARA SPVLAVRRRL
2470 2480 2490 2500 2510 2520
SSTLERLSSR LQRSGSSEDS GGASGRSTPL FGRLRRATSE GESLRRLGVP HNQLGSQTGA
2530 2540 2550 2560 2570 2580
TTPSAESLGS EASGTSGSSA PGESRSRHRW GLSRLRKDKG LSQPNLSSSV QEDLGHQYVP
2590 2600 2610 2620 2630 2640
SESDFPPVFH IKLKDQVLLE GEAATLLCLP AACPAPRISW MKDKQSLRSE PSVVIVSCKD
2650 2660 2670 2680 2690 2700
GRQLLSIPRA GKRHAGLYEC SATNVLGSIT SSCTVAVARI PGKLAPPEVP QTYHDTALVV
2710 2720 2730 2740 2750 2760
WKPGDGRAPC TYTLERRVDG ESVWHPVSSG IPDCYYNVTQ LPVGVTVRFR VACSNRAGQG
2770 2780 2790 2800 2810 2820
PFSNPSEKVF IRGTPDSPAQ PAAAPRDAPV TSGPTRAPPP DSPTSLAPTP ALAPPASQAS
2830 2840 2850 2860 2870 2880
TLSPSTSSMS ANQALSSLKA VGPPPATPPR KHRGLLATQQ AEPSPPSIVV TPSEPRSFVP
2890 2900 2910 2920 2930 2940
DTGTLTPTSS PQGVKPAPSS TSLYMVTSFV SAPPAPQAPA PEPPPEPTKV TVRSLSPAKE
2950 2960 2970 2980 2990 3000
VVSSPTPEST TLRQGPPQKP YTFLEEKARG RFGVVRSCRE NATGRTFVAK IVPYAAEGKR
3010 3020 3030 3040 3050 3060
RVLQEYEVLR TLHHERLMSL HEAYITPRYL VLIAESCGNR ELLCGLSDRF RYSEDDVATY
3070 3080 3090 3100 3110 3120
VVQLLQGLDY LHGHHVLHLD IKPDNLLLAA DNALKIVDFG SAQPYNPQAL KPLGHRTGTL
3130 3140 3150 3160 3170 3180
EFMAPEMVKG DPIGSATDIW GAGVLTYIML SGYSPFYEPD PQETEARIVG GRFDAFQLYP
3190 3200 3210 3220 3230 3240
NTSQSATLFL RKVLSVHPWS RPSLQDCLAH PWLQDAYLMK LRRQTLTFTT NRLKEFLGEQ
3250 3260
RRRRAEAATR HKVLLRSYPG SP
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q62407-1-unknown | MQKARG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90423 | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90424 | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000109219 | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000109218 | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000109217 | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000113646 | |||
| Q62407-855-unknown | MKLSPS... | 855 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt98956 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GTPEAS | 456 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000116953 | |||
| ...GTPEAS | 456 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt115769 | |||
| ...YPGSP | 3262 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...YPGSP | 3262 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86041 | |||
| ...YPGSP | 3262 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86042 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|