TopFIND 4.0

Q62962: Acid-sensing ion channel 2

General Information

Protein names
- Acid-sensing ion channel 2
- ASIC2
- Amiloride-sensitive brain sodium channel
- Amiloride-sensitive brain sodium channel 2
- Amiloride-sensitive cation channel 1, neuronal
- Amiloride-sensitive cation channel neuronal 1
- Brain sodium channel 1
- BNC1
- BNaC1
- Mammalian degenerin homolog {ECO:0000303|PubMed:8631835}
- MDEG {ECO:0000303|PubMed:8631835}
Gene names Asic2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q62962

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLKESPSEG SLQPSSIQIF ANTSTLHGIR HIFVYGPLTI RRVLWAVAFV GSLGLLLVES 
        70         80         90        100        110        120 
SERVSYYFSY QHVTKVDEVV AQSLVFPAVT LCNLNGFRFS RLTTNDLYHA GELLALLDVN 
       130        140        150        160        170        180 
LQIPDPHLAD PTVLEALRQK ANFKHYKPKQ FSMLEFLHRV GHDLKDMMLY CKFKGQECGH 
       190        200        210        220        230        240 
QDFTTVFTKY GKCYMFNSGE DGKPLLTTVK GGTGNGLEIM LDIQQDEYLP IWGETEETTF 
       250        260        270        280        290        300 
EAGVKVQIHS QSEPPFIQEL GFGVAPGFQT FVATQEQRLT YLPPPWGECR SSEMGLDFFP 
       310        320        330        340        350        360 
VYSITACRID CETRYIVENC NCRMVHMPGD APFCTPEQHK ECAEPALGLL AEKDSNYCLC 
       370        380        390        400        410        420 
RTPCNLTRYN KELSMVKIPS KTSAKYLEKK FNKSEKYISE NILVLDIFFE ALNYETIEQK 
       430        440        450        460        470        480 
KAYEVAALLG DIGGQMGLFI GASLLTILEL FDYIYELIKE KLLDLLGKEE EEGSHDENMS 
       490        500        510    
TCDTMPNHSE TISHTVNVPL QTALGTLEEI AC

Isoforms

- Isoform 2 of Acid-sensing ion channel 2

Sequence View

        10         20         30         40         50         60 
MDLKESPSEG SLQPSSIQIF ANTSTLHGIR HIFVYGPLTI RRVLWAVAFV GSLGLLLVES 
        70         80         90        100        110        120 
SERVSYYFSY QHVTKVDEVV AQSLVFPAVT LCNLNGFRFS RLTTNDLYHA GELLALLDVN 
       130        140        150        160        170        180 
LQIPDPHLAD PTVLEALRQK ANFKHYKPKQ FSMLEFLHRV GHDLKDMMLY CKFKGQECGH 
       190        200        210        220        230        240 
QDFTTVFTKY GKCYMFNSGE DGKPLLTTVK GGTGNGLEIM LDIQQDEYLP IWGETEETTF 
       250        260        270        280        290        300 
EAGVKVQIHS QSEPPFIQEL GFGVAPGFQT FVATQEQRLT YLPPPWGECR SSEMGLDFFP 
       310        320        330        340        350        360 
VYSITACRID CETRYIVENC NCRMVHMPGD APFCTPEQHK ECAEPALGLL AEKDSNYCLC 
       370        380        390        400        410        420 
RTPCNLTRYN KELSMVKIPS KTSAKYLEKK FNKSEKYISE NILVLDIFFE ALNYETIEQK 
       430        440        450        460        470        480 
KAYEVAALLG DIGGQMGLFI GASLLTILEL FDYIYELIKE KLLDLLGKEE EEGSHDENMS 
       490        500        510    
TCDTMPNHSE TISHTVNVPL QTALGTLEEI AC



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q62962-1-unknown MDLKES... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EEIAC 512 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EEIAC 512 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152222

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)