TopFIND 4.0

Q63054: Islet cell autoantigen 1

General Information

Protein names
- Islet cell autoantigen 1
- 69 kDa islet cell autoantigen
- ICA69
- Islet cell autoantigen p69
- ICAp69
- p69
Gene names Ica1 {ECO:0000312|RGD:621465}
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q63054

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGHKCYSWE LQDRFAQDKS VVNKMQQKYW ETKQAFIKAT GKKEDEHVVA SDADLDAKLE 
        70         80         90        100        110        120 
LFHSIQRTCL DLSKAIVLYQ KRICFLSQEE NELGKFLRSQ GFQDKTRAGK MMQATGKALC 
       130        140        150        160        170        180 
FSSQQRLALR NPLCRFHQEV ETFRHRAISD TWLTVNRMEQ CRTEYRGALL WMKDVSQELD 
       190        200        210        220        230        240 
PDLYKQMEKF RKVQTQVRLA KKNFDKLKMD VCQKVDLLGA SRCNLLSHML ATYQTTLLHF 
       250        260        270        280        290        300 
WEKTSHTMAA IHESFKGYQP YEFTTLKSLQ DPMKKLVEKE KKKSSRRENR EAVAQEPRQL 
       310        320        330        340        350        360 
ISLEEENQHK ESSTCQKEEG KSVPSSVDKS SADDACSGPI DELLDVKPEE ACLGPMAGTP 
       370        380        390        400        410        420 
EPESGDKDDL LLLNEIFSTS SLDEGEFSRE WAAVFGDDRL KEPAPMGAQG EPDPKPQIGS 
       430        440        450        460        470        480 
AFLPSQLLDQ NMKDLQASLQ EPAKAASDLT AWFSLFADLD PLSNPDAIGK TDKEHELLNA 
   

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q63054-1-unknown MSGHKC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ELLNA 480 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)