TopFIND 4.0

Q63120: Canalicular multispecific organic anion transporter 1 {ECO:0000305}

General Information

Protein names
- Canalicular multispecific organic anion transporter 1 {ECO:0000305}
- ATP-binding cassette sub-family C member 2
- Canalicular multidrug resistance protein
- Multidrug resistance-associated protein 2 {ECO:0000250|UniProtKB:Q92887}
- 7.6.2.2 {ECO:0000250|UniProtKB:Q92887}
Gene names Abcc2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q63120

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDKFCNSTFW DLSLLESPEA DLPLCFEQTV LVWIPLGFLW LLAPWQLYSV YRSRTKRSSI 
        70         80         90        100        110        120 
TKFYLAKQVF VVFLLILAAI DLSLALTEDT GQATVPPVRY TNPILYLCTW LLVLAVQHSR 
       130        140        150        160        170        180 
QWCVRKNSWF LSLFWILSVL CGVFQFQTLI RALLKDSKSN MAYSYLFFVS YGFQIVLLIL 
       190        200        210        220        230        240 
TAFSGPSDST QTPSVTASFL SSITFSWYDR TVLKGYKHPL TLEDVWDIDE GFKTRSVTSK 
       250        260        270        280        290        300 
FEAAMTKDLQ KARQAFQRRL QKSQRKPEAT LHGLNKKQSQ SQDVLVLEEA KKKSEKTTKD 
       310        320        330        340        350        360 
YPKSWLIKSL FKTFHVVILK SFILKLIHDL LVFLNPQLLK LLIGFVKSSN SYVWFGYICA 
       370        380        390        400        410        420 
ILMFAVTLIQ SFCLQSYFQH CFVLGMCVRT TVMSSIYKKA LTLSNLARKQ YTIGETVNLM 
       430        440        450        460        470        480 
SVDSQKLMDA TNYMQLVWSS VIQITLSIFF LWRELGPSIL AGVGVMVLLI PVNGVLATKI 
       490        500        510        520        530        540 
RNIQVQNMKN KDKRLKIMNE ILSGIKILKY FAWEPSFQEQ VQGIRKKELK NLLRFGQLQS 
       550        560        570        580        590        600 
LLIFILQITP ILVSVVTFSV YVLVDSANVL NAEKAFTSIT LFNILRFPLS MLPMVTSSIL 
       610        620        630        640        650        660 
QASVSVDRLE RYLGGDDLDT SAIRRVSNFD KAVKFSEASF TWDPDLEATI QDVNLDIKPG 
       670        680        690        700        710        720 
QLVAVVGTVG SGKSSLVSAM LGEMENVHGH ITIQGSTAYV PQQSWIQNGT IKDNILFGSE 
       730        740        750        760        770        780 
YNEKKYQQVL KACALLPDLE ILPGGDMAEI GEKGINLSGG QKQRVSLARA AYQDADIYIL 
       790        800        810        820        830        840 
DDPLSAVDAH VGKHIFNKVV GPNGLLAGKT RIFVTHGIHF LPQVDEIVVL GKGTILEKGS 
       850        860        870        880        890        900 
YRDLLDKKGV FARNWKTFMK HSGPEGEATV NNDSEAEDDD DGLIPTMEEI PEDAASLAMR 
       910        920        930        940        950        960 
RENSLRRTLS RSSRSSSRRG KSLKNSLKIK NVNVLKEKEK EVEGQKLIKK EFVETGKVKF 
       970        980        990       1000       1010       1020 
SIYLKYLQAV GWWSILFIIL FYGLNNVAFI GSNLWLSAWT SDSDNLNGTN NSSSHRDMRI 
      1030       1040       1050       1060       1070       1080 
GVFGALGLAQ GICLLISTLW SIYACRNASK ALHGQLLTNI LRAPMRFFDT TPTGRIVNRF 
      1090       1100       1110       1120       1130       1140 
SGDISTVDDL LPQTLRSWMM CFFGIAGTLV MICMATPVFA IIIIPLSILY ISVQVFYVAT 
      1150       1160       1170       1180       1190       1200 
SRQLRRLDSV TKSPIYSHFS ETVTGLPIIR AFEHQQRFLA WNEKQIDINQ KCVFSWITSN 
      1210       1220       1230       1240       1250       1260 
RWLAIRLELV GNLVVFCSAL LLVIYRKTLT GDVVGFVLSN ALNITQTLNW LVRMTSEAET 
      1270       1280       1290       1300       1310       1320 
NIVAVERISE YINVENEAPW VTDKRPPADW PRHGEIQFNN YQVRYRPELD LVLKGITCNI 
      1330       1340       1350       1360       1370       1380 
KSGEKVGVVG RTGAGKSSLT NCLFRILESA GGQIIIDGID VASIGLHDLR ERLTIIPQDP 
      1390       1400       1410       1420       1430       1440 
ILFSGSLRMN LDPFNKYSDE EVWRALELAH LRSFVSGLQL GLLSEVTEGG DNLSIGQRQL 
      1450       1460       1470       1480       1490       1500 
LCLGRAVLRK SKILVLDEAT AAVDLETDSL IQTTIRKEFS QCTVITIAHR LHTIMDSDKI 
      1510       1520       1530       1540    
MVLDNGKIVE YGSPEELLSN RGSFYLMAKE AGIENVNHTE L

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q63120-1-unknown MDKFCN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NHTEL 1541 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)