TopFIND 4.0

Q63673: Sonic hedgehog protein

General Information

Protein names
- Sonic hedgehog protein
- SHH
- Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains {ECO:0000250|UniProtKB:Q62226}
- ShhNC {ECO:0000250|UniProtKB:Q62226}
- Sonic hedgehog protein N-product
- ShhN
- Shh N-terminal processed signaling domains {ECO:0000250|UniProtKB:Q62226}
- ShhNp {ECO:0000250|UniProtKB:Q62226}
Gene names Shh
Organism Rattus norvegicus
Protease Family
Protease ID C46.002
Chromosome location
UniProt ID Q63673

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLLLLARCFL VALASSLLVC PGLACGPGRG FGKRQHPKKL TPLAYKQFIP NVAEKTLGAS 
        70         80         90        100        110        120 
GRYEGKITRN SERFKELTPN YNPDIIFKDE ENTGADRLMT QRCKDKLNAL AISVMNQWPG 
       130        140        150        160        170        180 
VKLRVTEGWD EDGHHSEESL HYEGRAVDIT TSDRDRSKYG MLARLAVEAG FDWVYYESKA 
       190        200        210        220        230        240 
RIHCSVKAEN SVAAKSDGCF PGSATVHLEQ GGTKLVKDLS PGDRVLAADD QGRLLYSDFL 
       250        260        270        280        290        300 
TFLDRDEGAK KVFYVIETRE PRERLLLTAA HLLFVAPHND SGPTPGPSPL FASRVRPGQR 
       310        320        330        340        350        360 
VYVVAERGGD RRLLPAAVHS VTLREEAAGA YAPLTADGTI LINRVLASCY AVIEEHSWAH 
       370        380        390        400        410        420 
RAFAPFRLAH ALLAALAPAR TDGGGGGSIP APQSVAEARG AGPPAGIHWY SQLLYHIGTW 
       430    
LLDSETLHPL GMAVKSS

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q63673-25-unknown CGPGRG... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q63673-199-unknown CFPGSA... 199 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AKSDGC 198 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...AVKSS 437 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)