Q63932: Dual specificity mitogen-activated protein kinase kinase 2
| Protein names | - Dual specificity mitogen-activated protein kinase kinase 2 - MAP kinase kinase 2 - MAPKK 2 - 2.7.12.2 {ECO:0000269|PubMed:10409742} - ERK activator kinase 2 - MAPK/ERK kinase 2 - MEK 2 |
|---|---|
| Gene names | Map2k2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q63932 |
3
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLARRKPVLP ALTINPTIAE GPSPTSEGAS EANLVDLQKK LEELDLDEQQ RKRLEAFLTQ
70 80 90 100 110 120
KAKVGELKDD DFERISELGA GNGGVVTKAR HRPSGLIMAR KLIHLEIKPA VRNQIIRELQ
130 140 150 160 170 180
VLHECNSPYI VGFYGAFYSD GEISICMEHM DGGSLDQVLK EAKRIPEDIL GKVSIAVLRG
190 200 210 220 230 240
LAYLREKHQI MHRDVKPSNI LVNSRGEIKL CDFGVSGQLI DSMANSFVGT RSYMSPERLQ
250 260 270 280 290 300
GTHYSVQSDI WSMGLSLVEL AIGRYPIPPP DAKELEASFG RPVVDGADGE PHSVSPRPRP
310 320 330 340 350 360
PGRPISVGHG MDSRPAMAIF ELLDYIVNEP PPKLPSGVFS SDFQEFVNKC LIKNPAERAD
370 380 390 400
LKLLMNHAFI KRSEGEEVDF AGWLCRTLRL KQPSTPTRTA V
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q63932-1-Acetylation | MLARRK... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
| Q63932-65-unknown | GELKDD... | 65 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q63932-98-unknown | MARKLI... | 98 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000117567 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...VLRGLA | 181 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000117567 | |||
| ...TRTAV | 401 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|