TopFIND 4.0

Q64364: Tumor suppressor ARF {ECO:0000305}

General Information

Protein names
- Tumor suppressor ARF {ECO:0000305}
- Alternative reading frame
- ARF
- Cyclin-dependent kinase inhibitor 2A
- p19ARF
Gene names Cdkn2a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q64364

6

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGRRFLVTVR IQRAGRPLQE RVFLVKFVRS RRPRTASCAL AFVNMLLRLE RILRRGPHRN 
        70         80         90        100        110        120 
PGPGDDDGQR SRSSSSAQLR CRFELRGPHY LLPPGARRSA GRLPGHAGGA ARVRGSAGCA 
       130        140        150        160    
RCLGSPAARL GPRAGTSRHR AIFAFRWVLF VFRWVVFVYR WERRPDRRA

Isoforms

- Isoform 4 of Cyclin-dependent kinase inhibitor 2A, isoform 3 - Isoform smARF of Tumor suppressor ARF

Sequence View

        10         20         30         40         50         60 
MGRRFLVTVR IQRAGRPLQE RVFLVKFVRS RRPRTASCAL AFVNMLLRLE RILRRGPHRN 
        70         80         90        100        110        120 
PGPGDDDGQR SRSSSSAQLR CRFELRGPHY LLPPGARRSA GRLPGHAGGA ARVRGSAGCA 
       130        140        150        160    
RCLGSPAARL GPRAGTSRHR AIFAFRWVLF VFRWVVFVYR WERRPDRRA         10         20         30         40         50         60 
MGRRFLVTVR IQRAGRPLQE RVFLVKFVRS RRPRTASCAL AFVNMLLRLE RILRRGPHRN 
        70         80         90        100        110        120 
PGPGDDDGQR SRSSSSAQLR CRFELRGPHY LLPPGARRSA GRLPGHAGGA ARVRGSAGCA 
       130        140        150        160    
RCLGSPAARL GPRAGTSRHR AIFAFRWVLF VFRWVVFVYR WERRPDRRA



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Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PDRRA 169 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PDRRA 169 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65547

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)