TopFIND 4.0

Q64449: C-type mannose receptor 2

General Information

Protein names
- C-type mannose receptor 2
- Lectin lambda
- Macrophage mannose receptor 2
- CD280
Gene names Mrc2
Organism Mus musculus
Protease Family
Protease ID I63.001
Chromosome location
UniProt ID Q64449

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVPIRPALAP WPRHLLRCVL LLGGLRLGHP ADSAAALLEP DVFLIFSQGM QGCLEAQGVQ 
        70         80         90        100        110        120 
VRVTPVCNAS LPAQRWKWVS RNRLFNLGAT QCLGTGWPVT NTTVSLGMYE CDREALSLRW 
       130        140        150        160        170        180 
QCRTLGDQLS LLLGARASNA SKPGTLERGD QTRSGHWNIY GSEEDLCARP YYEVYTIQGN 
       190        200        210        220        230        240 
SHGKPCTIPF KYDNQWFHGC TSTGREDGHL WCATTQDYGK DERWGFCPIK SNDCETFWDK 
       250        260        270        280        290        300 
DQLTDSCYQF NFQSTLSWRE AWASCEQQGA DLLSITEIHE QTYINGLLTG YSSTLWIGLN 
       310        320        330        340        350        360 
DLDTSGGWQW SDNSPLKYLN WESDQPDNPG EENCGVIRTE SSGGWQNHDC SIALPYVCKK 
       370        380        390        400        410        420 
KPNATVEPIQ PDRWTNVKVE CDPSWQPFQG HCYRLQAEKR SWQESKRACL RGGGDLLSIH 
       430        440        450        460        470        480 
SMAELEFITK QIKQEVEELW IGLNDLKLQM NFEWSDGSLV SFTHWHPFEP NNFRDSLEDC 
       490        500        510        520        530        540 
VTIWGPEGRW NDSPCNQSLP SICKKAGRLS QGAAEEDHGC RKGWTWHSPS CYWLGEDQVI 
       550        560        570        580        590        600 
YSDARRLCTD HGSQLVTITN RFEQAFVSSL IYNWEGEYFW TALQDLNSTG SFRWLSGDEV 
       610        620        630        640        650        660 
IYTHWNRDQP GYRRGGCVAL ATGSAMGLWE VKNCTSFRAR YICRQSLGTP VTPELPGPDP 
       670        680        690        700        710        720 
TPSLTGSCPQ GWVSDPKLRH CYKVFSSERL QEKKSWIQAL GVCRELGAQL LSLASYEEEH 
       730        740        750        760        770        780 
FVAHMLNKIF GESEPESHEQ HWFWIGLNRR DPREGHSWRW SDGLGFSYHN FARSRHDDDD 
       790        800        810        820        830        840 
IRGCAVLDLA SLQWVPMQCQ TQLDWICKIP RGVDVREPDI GRQGRLEWVR FQEAEYKFFE 
       850        860        870        880        890        900 
HHSSWAQAQR ICTWFQADLT SVHSQAELDF LGQNLQKLSS DQEQHWWIGL HTLESDGRFR 
       910        920        930        940        950        960 
WTDGSIINFI SWAPGKPRPI GKDKKCVYMT ARQEDWGDQR CHTALPYICK RSNSSGETQP 
       970        980        990       1000       1010       1020 
QDLPPSALGG CPSGWNQFLN KCFRIQGQDP QDRVKWSEAQ FSCEQQEAQL VTIANPLEQA 
      1030       1040       1050       1060       1070       1080 
FITASLPNVT FDLWIGLHAS QRDFQWIEQE PLLYTNWAPG EPSGPSPAPS GTKPTSCAVI 
      1090       1100       1110       1120       1130       1140 
LHSPSAHFTG RWDDRSCTEE THGFICQKGT DPSLSPSPAA TPPAPGAELS YLNHTFRLLQ 
      1150       1160       1170       1180       1190       1200 
KPLRWKDALL LCESRNASLA HVPDPYTQAF LTQAARGLQT PLWIGLASEE GSRRYSWLSE 
      1210       1220       1230       1240       1250       1260 
EPLNYVSWQD EEPQHSGGCA YVDVDGTWRT TSCDTKLQGA VCGVSRGPPP RRINYRGSCP 
      1270       1280       1290       1300       1310       1320 
QGLADSSWIP FREHCYSFHM EVLLGHKEAL QRCQKAGGTV LSILDEMENV FVWEHLQTAE 
      1330       1340       1350       1360       1370       1380 
AQSRGAWLGM NFNPKGGTLV WQDNTAVNYS NWGPPGLGPS MLSHNSCYWI QSSSGLWRPG 
      1390       1400       1410       1420       1430       1440 
ACTNITMGVV CKLPRVEENS FLPSAALPES PVALVVVLTA VLLLLALMTA ALILYRRRQS 
      1450       1460       1470    
AERGSFEGAR YSRSSHSGPA EATEKNILVS DMEMNEQQE

Isoforms

- Isoform 2 of C-type mannose receptor 2

Sequence View

        10         20         30         40         50         60 
MVPIRPALAP WPRHLLRCVL LLGGLRLGHP ADSAAALLEP DVFLIFSQGM QGCLEAQGVQ 
        70         80         90        100        110        120 
VRVTPVCNAS LPAQRWKWVS RNRLFNLGAT QCLGTGWPVT NTTVSLGMYE CDREALSLRW 
       130        140        150        160        170        180 
QCRTLGDQLS LLLGARASNA SKPGTLERGD QTRSGHWNIY GSEEDLCARP YYEVYTIQGN 
       190        200        210        220        230        240 
SHGKPCTIPF KYDNQWFHGC TSTGREDGHL WCATTQDYGK DERWGFCPIK SNDCETFWDK 
       250        260        270        280        290        300 
DQLTDSCYQF NFQSTLSWRE AWASCEQQGA DLLSITEIHE QTYINGLLTG YSSTLWIGLN 
       310        320        330        340        350        360 
DLDTSGGWQW SDNSPLKYLN WESDQPDNPG EENCGVIRTE SSGGWQNHDC SIALPYVCKK 
       370        380        390        400        410        420 
KPNATVEPIQ PDRWTNVKVE CDPSWQPFQG HCYRLQAEKR SWQESKRACL RGGGDLLSIH 
       430        440        450        460        470        480 
SMAELEFITK QIKQEVEELW IGLNDLKLQM NFEWSDGSLV SFTHWHPFEP NNFRDSLEDC 
       490        500        510        520        530        540 
VTIWGPEGRW NDSPCNQSLP SICKKAGRLS QGAAEEDHGC RKGWTWHSPS CYWLGEDQVI 
       550        560        570        580        590        600 
YSDARRLCTD HGSQLVTITN RFEQAFVSSL IYNWEGEYFW TALQDLNSTG SFRWLSGDEV 
       610        620        630        640        650        660 
IYTHWNRDQP GYRRGGCVAL ATGSAMGLWE VKNCTSFRAR YICRQSLGTP VTPELPGPDP 
       670        680        690        700        710        720 
TPSLTGSCPQ GWVSDPKLRH CYKVFSSERL QEKKSWIQAL GVCRELGAQL LSLASYEEEH 
       730        740        750        760        770        780 
FVAHMLNKIF GESEPESHEQ HWFWIGLNRR DPREGHSWRW SDGLGFSYHN FARSRHDDDD 
       790        800        810        820        830        840 
IRGCAVLDLA SLQWVPMQCQ TQLDWICKIP RGVDVREPDI GRQGRLEWVR FQEAEYKFFE 
       850        860        870        880        890        900 
HHSSWAQAQR ICTWFQADLT SVHSQAELDF LGQNLQKLSS DQEQHWWIGL HTLESDGRFR 
       910        920        930        940        950        960 
WTDGSIINFI SWAPGKPRPI GKDKKCVYMT ARQEDWGDQR CHTALPYICK RSNSSGETQP 
       970        980        990       1000       1010       1020 
QDLPPSALGG CPSGWNQFLN KCFRIQGQDP QDRVKWSEAQ FSCEQQEAQL VTIANPLEQA 
      1030       1040       1050       1060       1070       1080 
FITASLPNVT FDLWIGLHAS QRDFQWIEQE PLLYTNWAPG EPSGPSPAPS GTKPTSCAVI 
      1090       1100       1110       1120       1130       1140 
LHSPSAHFTG RWDDRSCTEE THGFICQKGT DPSLSPSPAA TPPAPGAELS YLNHTFRLLQ 
      1150       1160       1170       1180       1190       1200 
KPLRWKDALL LCESRNASLA HVPDPYTQAF LTQAARGLQT PLWIGLASEE GSRRYSWLSE 
      1210       1220       1230       1240       1250       1260 
EPLNYVSWQD EEPQHSGGCA YVDVDGTWRT TSCDTKLQGA VCGVSRGPPP RRINYRGSCP 
      1270       1280       1290       1300       1310       1320 
QGLADSSWIP FREHCYSFHM EVLLGHKEAL QRCQKAGGTV LSILDEMENV FVWEHLQTAE 
      1330       1340       1350       1360       1370       1380 
AQSRGAWLGM NFNPKGGTLV WQDNTAVNYS NWGPPGLGPS MLSHNSCYWI QSSSGLWRPG 
      1390       1400       1410       1420       1430       1440 
ACTNITMGVV CKLPRVEENS FLPSAALPES PVALVVVLTA VLLLLALMTA ALILYRRRQS 
      1450       1460       1470    
AERGSFEGAR YSRSSHSGPA EATEKNILVS DMEMNEQQE



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q64449-1-unknown MVPIRP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81512
    Q64449-31-unknown ADSAAA... 31 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q64449-31-unknown ADSAAA... 31 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114840

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NEQQE 1479 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)