TopFIND 4.0

Q64LD2: WD repeat-containing protein 25

General Information

Protein names
- WD repeat-containing protein 25
Gene names WDR25
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q64LD2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTARTLSLMA SLVAYDDSDS EAETEHAGSF NATGQQKDTS GVARPPGQDF ASGTLDVPKA 
        70         80         90        100        110        120 
GAQPTKHGSC EDPGGYRLPL AQLGRSDWGS CPSQRLQWPG KEPQVTFPIK EPSCSSLWTS 
       130        140        150        160        170        180 
HVPASHMPLA AARFKQVKLS RNFPKSSFHA QSESETVGKN GSSFQKKKCE DCVVPYTPRR 
       190        200        210        220        230        240 
LRQRQALSTE TGKGKDVEPQ GPPAGRAPAP LYVGPGVSEF IQPYLNSHYK ETTVPRKVLF 
       250        260        270        280        290        300 
HLRGHRGPVN TIQWCPVLSK SHMLLSTSMD KTFKVWNAVD SGHCLQTYSL HTEAVRAARW 
       310        320        330        340        350        360 
APCGRRILSG GFDFALHLTD LETGTQLFSG RSDFRITTLK FHPKDHNIFL CGGFSSEMKA 
       370        380        390        400        410        420 
WDIRTGKVMR SYKATIQQTL DILFLREGSE FLSSTDASTR DSADRTIIAW DFRTSAKISN 
       430        440        450        460        470        480 
QIFHERFTCP SLALHPREPV FLAQTNGNYL ALFSTVWPYR MSRRRRYEGH KVEGYSVGCE 
       490        500        510        520        530        540 
CSPGGDLLVT GSADGRVLMY SFRTASRACT LQGHTQACVG TTYHPVLPSV LATCSWGGDM 
   
KIWH

Isoforms

- Isoform 2 of WD repeat-containing protein 25

Sequence View

        10         20         30         40         50         60 
MTARTLSLMA SLVAYDDSDS EAETEHAGSF NATGQQKDTS GVARPPGQDF ASGTLDVPKA 
        70         80         90        100        110        120 
GAQPTKHGSC EDPGGYRLPL AQLGRSDWGS CPSQRLQWPG KEPQVTFPIK EPSCSSLWTS 
       130        140        150        160        170        180 
HVPASHMPLA AARFKQVKLS RNFPKSSFHA QSESETVGKN GSSFQKKKCE DCVVPYTPRR 
       190        200        210        220        230        240 
LRQRQALSTE TGKGKDVEPQ GPPAGRAPAP LYVGPGVSEF IQPYLNSHYK ETTVPRKVLF 
       250        260        270        280        290        300 
HLRGHRGPVN TIQWCPVLSK SHMLLSTSMD KTFKVWNAVD SGHCLQTYSL HTEAVRAARW 
       310        320        330        340        350        360 
APCGRRILSG GFDFALHLTD LETGTQLFSG RSDFRITTLK FHPKDHNIFL CGGFSSEMKA 
       370        380        390        400        410        420 
WDIRTGKVMR SYKATIQQTL DILFLREGSE FLSSTDASTR DSADRTIIAW DFRTSAKISN 
       430        440        450        460        470        480 
QIFHERFTCP SLALHPREPV FLAQTNGNYL ALFSTVWPYR MSRRRRYEGH KVEGYSVGCE 
       490        500        510        520        530        540 
CSPGGDLLVT GSADGRVLMY SFRTASRACT LQGHTQACVG TTYHPVLPSV LATCSWGGDM 
   
KIWH



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q64LD2-1-unknown MTARTL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q64LD2-152- SESETV... 152 Subtiligase Based Positive Selection Wells apoptotic_MM1s_bort 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MKIWH 544 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...MKIWH 544 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt90041

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)