TopFIND 4.0

Q687X5: Metalloreductase STEAP4

General Information

Protein names
- Metalloreductase STEAP4
- 1.16.1.9 {ECO:0000269|PubMed:30337524}
- Six-transmembrane epithelial antigen of prostate 4
- SixTransMembrane protein of prostate 2
- Tumor necrosis factor, alpha-induced protein 9
Gene names STEAP4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q687X5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEKTCIDALP LTMNSSEKQE TVCIFGTGDF GRSLGLKMLQ CGYSVVFGSR NPQKTTLLPS 
        70         80         90        100        110        120 
GAEVLSYSEA AKKSGIIIIA IHREHYDFLT ELTEVLNGKI LVDISNNLKI NQYPESNAEY 
       130        140        150        160        170        180 
LAHLVPGAHV VKAFNTISAW ALQSGALDAS RQVFVCGNDS KAKQRVMDIV RNLGLTPMDQ 
       190        200        210        220        230        240 
GSLMAAKEIE KYPLQLFPMW RFPFYLSAVL CVFLFFYCVI RDVIYPYVYE KKDNTFRMAI 
       250        260        270        280        290        300 
SIPNRIFPIT ALTLLALVYL PGVIAAILQL YRGTKYRRFP DWLDHWMLCR KQLGLVALGF 
       310        320        330        340        350        360 
AFLHVLYTLV IPIRYYVRWR LGNLTVTQAI LKKENPFSTS SAWLSDSYVA LGILGFFLFV 
       370        380        390        400        410        420 
LLGITSLPSV SNAVNWREFR FVQSKLGYLT LILCTAHTLV YGGKRFLSPS NLRWYLPAAY 
       430        440        450    
VLGLIIPCTV LVIKFVLIMP CVDNTLTRIR QGWERNSKH

Isoforms

- Isoform 2 of Metalloreductase STEAP4

Sequence View

        10         20         30         40         50         60 
MEKTCIDALP LTMNSSEKQE TVCIFGTGDF GRSLGLKMLQ CGYSVVFGSR NPQKTTLLPS 
        70         80         90        100        110        120 
GAEVLSYSEA AKKSGIIIIA IHREHYDFLT ELTEVLNGKI LVDISNNLKI NQYPESNAEY 
       130        140        150        160        170        180 
LAHLVPGAHV VKAFNTISAW ALQSGALDAS RQVFVCGNDS KAKQRVMDIV RNLGLTPMDQ 
       190        200        210        220        230        240 
GSLMAAKEIE KYPLQLFPMW RFPFYLSAVL CVFLFFYCVI RDVIYPYVYE KKDNTFRMAI 
       250        260        270        280        290        300 
SIPNRIFPIT ALTLLALVYL PGVIAAILQL YRGTKYRRFP DWLDHWMLCR KQLGLVALGF 
       310        320        330        340        350        360 
AFLHVLYTLV IPIRYYVRWR LGNLTVTQAI LKKENPFSTS SAWLSDSYVA LGILGFFLFV 
       370        380        390        400        410        420 
LLGITSLPSV SNAVNWREFR FVQSKLGYLT LILCTAHTLV YGGKRFLSPS NLRWYLPAAY 
       430        440        450    
VLGLIIPCTV LVIKFVLIMP CVDNTLTRIR QGWERNSKH



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q687X5-1-unknown MEKTCI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q687X5-1-unknown MEKTCI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90907

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RNSKH 459 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RNSKH 459 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt86525

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)