TopFIND 4.0

Q68DK7: Male-specific lethal 1 homolog

General Information

Protein names
- Male-specific lethal 1 homolog
- MSL-1
- Male-specific lethal 1-like 1
- MSL1-like 1
- Male-specific lethal-1 homolog 1
Gene names MSL1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q68DK7

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTMRSAVFKA AAAPAGGNPE QRLDYERAAA LGGPEDEPGA AEAHFLPRHR KLKEPGPPLA 
        70         80         90        100        110        120 
SSQGGSPAPS PAGCGGKGRG LLLPAGAAPG QQEESWGGSV PLPCPPPATK QAGIGGEPAA 
       130        140        150        160        170        180 
AGAGCSPRPK YQAVLPIQTG SLVAAAKEPT PWAGDKGGAA SPAATASDPA GPPPLPLPGP 
       190        200        210        220        230        240 
PPLAPTATAG TLAASEGRWK SMRKSPLGGG GGSGASSQAA CLKQILLLQL DLIEQQQQQL 
       250        260        270        280        290        300 
QAKEKEIEEL KSERDTLLAR IERMERRMQL VKKDNEKERH KLFQGYETEE REETELSEKI 
       310        320        330        340        350        360 
KLECQPELSE TSQTLPPKPF SCGRSGKGHK RKSPFGSTER KTPVKKLAPE FSKVKTKTPK 
       370        380        390        400        410        420 
HSPIKEEPCG SLSETVCKRE LRSQETPEKP RSSVDTPPRL STPQKGPSTH PKEKAFSSEI 
       430        440        450        460        470        480 
EDLPYLSTTE MYLCRWHQPP PSPLPLRESS PKKEETVARC LMPSSVAGET SVLAVPSWRD 
       490        500        510        520        530        540 
HSVEPLRDPN PSDLLENLDD SVFSKRHAKL ELDEKRRKRW DIQRIREQRI LQRLQLRMYK 
       550        560        570        580        590        600 
KKGIQESEPE VTSFFPEPDD VESLMITPFL PVVAFGRPLP KLTPQNFELP WLDERSRCRL 
       610    
EIQKKQTPHR TCRK

Isoforms

- Isoform 2 of Male-specific lethal 1 homolog - Isoform 3 of Male-specific lethal 1 homolog

Sequence View

        10         20         30         40         50         60 
MTMRSAVFKA AAAPAGGNPE QRLDYERAAA LGGPEDEPGA AEAHFLPRHR KLKEPGPPLA 
        70         80         90        100        110        120 
SSQGGSPAPS PAGCGGKGRG LLLPAGAAPG QQEESWGGSV PLPCPPPATK QAGIGGEPAA 
       130        140        150        160        170        180 
AGAGCSPRPK YQAVLPIQTG SLVAAAKEPT PWAGDKGGAA SPAATASDPA GPPPLPLPGP 
       190        200        210        220        230        240 
PPLAPTATAG TLAASEGRWK SMRKSPLGGG GGSGASSQAA CLKQILLLQL DLIEQQQQQL 
       250        260        270        280        290        300 
QAKEKEIEEL KSERDTLLAR IERMERRMQL VKKDNEKERH KLFQGYETEE REETELSEKI 
       310        320        330        340        350        360 
KLECQPELSE TSQTLPPKPF SCGRSGKGHK RKSPFGSTER KTPVKKLAPE FSKVKTKTPK 
       370        380        390        400        410        420 
HSPIKEEPCG SLSETVCKRE LRSQETPEKP RSSVDTPPRL STPQKGPSTH PKEKAFSSEI 
       430        440        450        460        470        480 
EDLPYLSTTE MYLCRWHQPP PSPLPLRESS PKKEETVARC LMPSSVAGET SVLAVPSWRD 
       490        500        510        520        530        540 
HSVEPLRDPN PSDLLENLDD SVFSKRHAKL ELDEKRRKRW DIQRIREQRI LQRLQLRMYK 
       550        560        570        580        590        600 
KKGIQESEPE VTSFFPEPDD VESLMITPFL PVVAFGRPLP KLTPQNFELP WLDERSRCRL 
       610    
EIQKKQTPHR TCRK         10         20         30         40         50         60 
MTMRSAVFKA AAAPAGGNPE QRLDYERAAA LGGPEDEPGA AEAHFLPRHR KLKEPGPPLA 
        70         80         90        100        110        120 
SSQGGSPAPS PAGCGGKGRG LLLPAGAAPG QQEESWGGSV PLPCPPPATK QAGIGGEPAA 
       130        140        150        160        170        180 
AGAGCSPRPK YQAVLPIQTG SLVAAAKEPT PWAGDKGGAA SPAATASDPA GPPPLPLPGP 
       190        200        210        220        230        240 
PPLAPTATAG TLAASEGRWK SMRKSPLGGG GGSGASSQAA CLKQILLLQL DLIEQQQQQL 
       250        260        270        280        290        300 
QAKEKEIEEL KSERDTLLAR IERMERRMQL VKKDNEKERH KLFQGYETEE REETELSEKI 
       310        320        330        340        350        360 
KLECQPELSE TSQTLPPKPF SCGRSGKGHK RKSPFGSTER KTPVKKLAPE FSKVKTKTPK 
       370        380        390        400        410        420 
HSPIKEEPCG SLSETVCKRE LRSQETPEKP RSSVDTPPRL STPQKGPSTH PKEKAFSSEI 
       430        440        450        460        470        480 
EDLPYLSTTE MYLCRWHQPP PSPLPLRESS PKKEETVARC LMPSSVAGET SVLAVPSWRD 
       490        500        510        520        530        540 
HSVEPLRDPN PSDLLENLDD SVFSKRHAKL ELDEKRRKRW DIQRIREQRI LQRLQLRMYK 
       550        560        570        580        590        600 
KKGIQESEPE VTSFFPEPDD VESLMITPFL PVVAFGRPLP KLTPQNFELP WLDERSRCRL 
       610    
EIQKKQTPHR TCRK



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q68DK7-1-unknown MTMRSA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q68DK7-202-unknown MRKSPL... 202 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81616
    Q68DK7-264-unknown MERRMQ... 264 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81617
    Q68DK7-264-unknown MERRMQ... 264 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt107587

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)