TopFIND 4.0

Q68EJ0: Cytochrome b5 reductase 4

General Information

Protein names
- Cytochrome b5 reductase 4
- 1.6.2.2
- Flavohemoprotein b5/b5R
- b5+b5R
- N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein
- cb5/cb5R
Gene names Cyb5r4
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q68EJ0

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLNVPSQAFP APGSQQRVAS QGRSKVPLKQ GRSLMDWFRL TKSGKDFTGL KGGLIEVTEE 
        70         80         90        100        110        120 
ELKKHNKKDD CWICIRGFVY NVSPYMEYHP GGEDELMRAA GADGTDLFNE VHRWVNYESM 
       130        140        150        160        170        180 
LKECLVGRMA VKPAVPKDCH EGKRVLNGML PKSQVTDTLP REGPSSPSYD WFQTESSVTI 
       190        200        210        220        230        240 
VIYTKQKNIN LDSVIVDLQD DSLRAEAVIK DHSYLIHIGL SHEVQENFSV RVIENVGKIE 
       250        260        270        280        290        300 
IVLQKKETVS WKCLGDPLEK HDSFIPKKDT GLYYRQCQLI SKEDVTHDTR LFCLMLPPST 
       310        320        330        340        350        360 
HLQVPVGQHV YLKLSVTGAE IVKPYTPVSE SLLSDFKEPV LSPNKYIYFL IKIYPAGLFT 
       370        380        390        400        410        420 
PELDRLQIGD FVSVSGPEGN FKVSKLQEVE DLFLLAAGTG FTPMVTVLNH ALTHMSSLRK 
       430        440        450        460        470        480 
VKLMFFNKTE DDIIWRCQLE KLALKDKRFH VEYVLSAPSP EWNGKQGHVS RALLSEFLQR 
       490        500        510        520    
SLENSKVFLC ICGPTPFTDE GIRLLHDLNF SDDEIHGFTA 

Isoforms

- Isoform 2 of Cytochrome b5 reductase 4

Sequence View

        10         20         30         40         50         60 
MLNVPSQAFP APGSQQRVAS QGRSKVPLKQ GRSLMDWFRL TKSGKDFTGL KGGLIEVTEE 
        70         80         90        100        110        120 
ELKKHNKKDD CWICIRGFVY NVSPYMEYHP GGEDELMRAA GADGTDLFNE VHRWVNYESM 
       130        140        150        160        170        180 
LKECLVGRMA VKPAVPKDCH EGKRVLNGML PKSQVTDTLP REGPSSPSYD WFQTESSVTI 
       190        200        210        220        230        240 
VIYTKQKNIN LDSVIVDLQD DSLRAEAVIK DHSYLIHIGL SHEVQENFSV RVIENVGKIE 
       250        260        270        280        290        300 
IVLQKKETVS WKCLGDPLEK HDSFIPKKDT GLYYRQCQLI SKEDVTHDTR LFCLMLPPST 
       310        320        330        340        350        360 
HLQVPVGQHV YLKLSVTGAE IVKPYTPVSE SLLSDFKEPV LSPNKYIYFL IKIYPAGLFT 
       370        380        390        400        410        420 
PELDRLQIGD FVSVSGPEGN FKVSKLQEVE DLFLLAAGTG FTPMVTVLNH ALTHMSSLRK 
       430        440        450        460        470        480 
VKLMFFNKTE DDIIWRCQLE KLALKDKRFH VEYVLSAPSP EWNGKQGHVS RALLSEFLQR 
       490        500        510        520    
SLENSKVFLC ICGPTPFTDE GIRLLHDLNF SDDEIHGFTA 



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q68EJ0-1-Acetylation MLNVPS... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q68EJ0-1-Acetylation MLNVPS... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193949
    Q68EJ0-1-unknown MLNVPS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193039

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HGFTA 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HGFTA 520 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152985

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)