Q68FD5: Clathrin heavy chain 1
| Protein names | - Clathrin heavy chain 1 |
|---|---|
| Gene names | Cltc |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q68FD5 |
10
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAQILPIRFQ EHLQLQNLGI NPANIGFSTL TMESDKFICI REKVGEQAQV VIIDMNDPSN
70 80 90 100 110 120
PIRRPISADS AIMNPASKVI ALKAGKTLQI FNIEMKSKMK AHTMTDDVTF WKWISLNTVA
130 140 150 160 170 180
LVTDNAVYHW SMEGESQPVK MFDRHSSLAG CQIINYRTDA KQKWLLLTGI SAQQNRVVGA
190 200 210 220 230 240
MQLYSVDRKV SQPIEGHAAS FAQFKMEGNA EESTLFCFAV RGQAGGKLHI IEVGTPPTGN
250 260 270 280 290 300
QPFPKKAVDV FFPPEAQNDF PVAMQISEKH DVVFLITKYG YIHLYDLETG TCIYMNRISG
310 320 330 340 350 360
ETIFVTAPHE ATAGIIGVNR KGQVLSVCVE EENIIPYITN VLQNPDLALR MAVRNNLAGA
370 380 390 400 410 420
EELFARKFNA LFAQGNYSEA AKVAANAPKG ILRTPDTIRR FQSVPAQPGQ TSPLLQYFGI
430 440 450 460 470 480
LLDQGQLNKY ESLELCRPVL QQGRKQLLEK WLKEDKLECS EELGDLVKSV DPTLALSVYL
490 500 510 520 530 540
RANVPNKVIQ CFAETGQVQK IVLYAKKVGY TPDWIFLLRN VMRISPDQGQ QFAQMLVQDE
550 560 570 580 590 600
EPLADITQIV DVFMEYNLIQ QCTAFLLDAL KNNRPSEGPL QTRLLEMNLM HAPQVADAIL
610 620 630 640 650 660
GNQMFTHYDR AHIAQLCEKA GLLQRALEHF TDLYDIKRAV VHTHLLNPEW LVNYFGSLSV
670 680 690 700 710 720
EDSLECLRAM LSANIRQNLQ ICVQVASKYH EQLSTQSLIE LFESFKSFEG LFYFLGSIVN
730 740 750 760 770 780
FSQDPDVHFK YIQAACKTGQ IKEVERICRE SNCYDPERVK NFLKEAKLTD QLPLIIVCDR
790 800 810 820 830 840
FDFVHDLVLY LYRNNLQKYI EIYVQKVNPS RLPVVIGGLL DVDCSEDVIK NLILVVRGQF
850 860 870 880 890 900
STDELVAEVE KRNRLKLLLP WLEARIHEGC EEPATHNALA KIYIDSNNNP ERFLRENPYY
910 920 930 940 950 960
DSRVVGKYCE KRDPHLACVA YERGQCDLEL INVCNENSLF KSLSRYLVRR KDPELWGSVL
970 980 990 1000 1010 1020
LESNPYRRPL IDQVVQTALS ETQDPEEVSV TVKAFMTADL PNELIELLEK IVLDNSVFSE
1030 1040 1050 1060 1070 1080
HRNLQNLLIL TAIKADRTRV MEYINRLDNY DAPDIANIAI SNELFEEAFA IFRKFDVNTS
1090 1100 1110 1120 1130 1140
AVQVLIEHIG NLDRAYEFAE RCNEPAVWSQ LAKAQLQKGM VKEAIDSYIK ADDPSSYMEV
1150 1160 1170 1180 1190 1200
VQAANASGNW EELVKYLQMA RKKARESYVE TELIFALAKT NRLAELEEFI NGPNNAHIQQ
1210 1220 1230 1240 1250 1260
VGDRCYDEKM YDAAKLLYNN VSNFGRLAST LVHLGEYQAA VDGARKANST RTWKEVCFAC
1270 1280 1290 1300 1310 1320
VDGKEFRLAQ MCGLHIVVHA DELEELINYY QDRGYFEELI TMLEAALGLE RAHMGMFTEL
1330 1340 1350 1360 1370 1380
AILYSKFKPQ KMREHLELFW SRVNIPKVLR AAEQAHLWAE LVFLYDKYEE YDNAIITMMN
1390 1400 1410 1420 1430 1440
HPTDAWKEGQ FKDIITKVAN VELYYKAIQF YLEFKPLLLN DLLMVLSPRL DHTRAVNYFS
1450 1460 1470 1480 1490 1500
KVKQLPLVKP YLRSVQNHNN KSVNESLNNL FITEEDYQAL RTSIDAYDNF DNISLAQRLE
1510 1520 1530 1540 1550 1560
KHELIEFRRI AAYLFKGNNR WKQSVELCKK DSLYKDAMQY ASESKDTELA EELLQWFLQE
1570 1580 1590 1600 1610 1620
EKRECFGACL FTCYDLLRPD VVLETAWRHN IMDFAMPYFI QVMKEYLTKV DKLDASESLR
1630 1640 1650 1660 1670
KEEEQATETQ PIVYGQPQLM LTAGPSVAVP PQAPFGYGYT APPYGQPQPG FGYSM
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
10 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q68FD5-2-unknown | MAQILP... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
| Q68FD5-2-unknown | MAQILP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q68FD5-2-Acetylation | AQILPI... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
| Q68FD5-2-Acetylation | AQILPI... | 2 | acetylation- | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | ||
| Q68FD5-164-unknown | WLLLTG... | 164 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q68FD5-167-unknown | LTGISA... | 167 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30589 | |||
| Q68FD5-169-unknown | GISAQQ... | 169 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q68FD5-249-unknown | DVFFPP... | 249 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q68FD5-355-unknown | NNLAGA... | 355 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q68FD5-378-unknown | SEAAKV... | 378 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30590 | |||
| Q68FD5-765-unmodified | EAKLTD... | 765 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
| Q68FD5-1472-unknown | ITEEDY... | 1472 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30591 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...QKWLLL | 166 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30589 | |||
| ...AQGNYS | 377 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30590 | |||
| ...LNNLFI | 1471 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30591 | |||
| ...FGYSM | 1675 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATE_MOUSE | 166 | WLLL.|.LTGI | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> CLH1_MOUSE @166 | ||
| CATE_MOUSE | 377 | GNYS.|.SEAA | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> CLH1_MOUSE @377 | ||
| CATE_MOUSE | 1471 | NLFI.|.ITEE | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> CLH1_MOUSE @1471 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|