TopFIND 4.0

Q69ZH9: Rho GTPase-activating protein 23

General Information

Protein names
- Rho GTPase-activating protein 23
- Rho-type GTPase-activating protein 23
Gene names Arhgap23
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q69ZH9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNGVAFCLVG IPPRPEPRPP QLPLGPRDGC SSGRPLPWPG PRTLLLRKSL QDGFGFTLRH 
        70         80         90        100        110        120 
FIVYPPESAV HCILKEEENG GRGGGPSPRH RLEPMDTIFV KNVKDGGPAH RAGLRTGDRL 
       130        140        150        160        170        180 
VKVNGESIIG KTYSQVIGLI QNSDDTLELS IMPKDEDILQ LAYSQDAYLK GNEPYSGEAR 
       190        200        210        220        230        240 
SIPEPPPLCY PRKTYAPPTR APAWATMVPE PISALPPDPR SPAAWSDPGS RVPSATRAHL 
       250        260        270        280        290        300 
DNSSLGMSQP RPSPGAFPHL PSESRTPRAF PEPGSRVLPS RLECQQALSH WLSNQIPRRA 
       310        320        330        340        350        360 
GERRCPAMPP RARSASQDRL EDVTTHHPWP CSTSQDALSQ LGQEGWHRAR SDDYLSRATR 
       370        380        390        400        410        420 
SAEALGPGAL VSPRLERCGW ASQRPSARTS ACPSRDLTQA PPPSGLQGLD DIGYIGYRSY 
       430        440        450        460        470        480 
SPSFQRRTGL LHALSFRDSP FGGLPTFSLA QSPASFPPEA SEPPRVVRPD PSTRALEPPA 
       490        500        510        520        530        540 
EDHRDEVVLR QKPPTGRKVQ LTPARQMNLG FGDESPEPEA RGERLGRKVA PLATTEDSLA 
       550        560        570        580        590        600 
SIPFIDEPTS PSIDLQAKHV PASAVVSSAM NSAPVLGTSP SSPTFTFALS RHYSQDCSSI 
       610        620        630        640        650        660 
KAGRRSSYLL AITTERSKSC DDGLNTFRDE GRVLRRLPSR VPSLRVLRSF FTDGSLDSWG 
       670        680        690        700        710        720 
TSEDADAPSK RHSTSDLSDA TFSDIRREGW LYYKQILTKK GKKAGGGLRQ WKRVYAVLRA 
       730        740        750        760        770        780 
RSLSLSKERR EPGPAAAGAA AAGAGEDEAA PVCIGSCLVD ISYSETKRRH VFRLTTADFC 
       790        800        810        820        830        840 
EYLFQAEDRD DMLGWIRAIR ENSRAEGEDP GCANQALISK KLNDYRKVSH SSGPKADSSP 
       850        860        870        880        890        900 
KGSRGLGGLK SEFLKQTAVR GLRTQEQPPG SKEDSVAAPK TPWGINIIKK NKKAAPRAFG 
       910        920        930        940        950        960 
IRLEECQPAT ENQRVPLIVA ACCRIVEARG LESTGIYRVP GNNAVVSSLQ EQLNRGPSDI 
       970        980        990       1000       1010       1020 
NLQDERWQDL NVISSLLKAF FRKLPEPLFT DDKYNDFIEA NRIEDSRERM KTLRKLIRDL 
      1030       1040       1050       1060       1070       1080 
PGHYYETLKF LVGHLKTIAD HSEKNKMEPR NLALVFGPTL VRTSEDNMTD MVTHMPDRYK 
      1090       1100       1110       1120       1130       1140 
IVETLIQHSD WFFSDDEDKG ERTPVDDKEP QSVPNIEYLL PNIGRTVPPS DPGSDSTTCS 
      1150       1160       1170       1180       1190       1200 
SAKSKGSWVP KKEPYAREML AISFISAVNR KRKKRREARG LGSSTDDDSE QEAHKAAVGT 
      1210       1220       1230       1240       1250       1260 
QEPPEGQLPG PAAEEAPGRL SPPTAPDERP AADTRSIVSG YSTLSTMDRS VCSGTGGRRA 
      1270       1280       1290       1300       1310       1320 
GAGDEADDER SELSHVETDT EGGAGPGGRL SRRPSFSSHH LMPCDTLARR RLSRSRAEAE 
      1330       1340       1350       1360       1370       1380 
GPGAGTARAC PRGPEPPGSA SSSSQESLRP PAAAPALGSR PSRVEALRLR LRGTADDMLA 
      1390       1400       1410       1420       1430       1440 
VRLRRPLSPE TRRRRSSWRR HTVVVQSPLT DLNFNEWKEL GGGGPQESVG VRPHSDNKDS 
      1450       1460       1470       1480    
GLSSLESTKA RASSAASLPS GDLGALQGLP QRRSAAARLH QCL

Isoforms

- Isoform 2 of Rho GTPase-activating protein 23

Sequence View

        10         20         30         40         50         60 
MNGVAFCLVG IPPRPEPRPP QLPLGPRDGC SSGRPLPWPG PRTLLLRKSL QDGFGFTLRH 
        70         80         90        100        110        120 
FIVYPPESAV HCILKEEENG GRGGGPSPRH RLEPMDTIFV KNVKDGGPAH RAGLRTGDRL 
       130        140        150        160        170        180 
VKVNGESIIG KTYSQVIGLI QNSDDTLELS IMPKDEDILQ LAYSQDAYLK GNEPYSGEAR 
       190        200        210        220        230        240 
SIPEPPPLCY PRKTYAPPTR APAWATMVPE PISALPPDPR SPAAWSDPGS RVPSATRAHL 
       250        260        270        280        290        300 
DNSSLGMSQP RPSPGAFPHL PSESRTPRAF PEPGSRVLPS RLECQQALSH WLSNQIPRRA 
       310        320        330        340        350        360 
GERRCPAMPP RARSASQDRL EDVTTHHPWP CSTSQDALSQ LGQEGWHRAR SDDYLSRATR 
       370        380        390        400        410        420 
SAEALGPGAL VSPRLERCGW ASQRPSARTS ACPSRDLTQA PPPSGLQGLD DIGYIGYRSY 
       430        440        450        460        470        480 
SPSFQRRTGL LHALSFRDSP FGGLPTFSLA QSPASFPPEA SEPPRVVRPD PSTRALEPPA 
       490        500        510        520        530        540 
EDHRDEVVLR QKPPTGRKVQ LTPARQMNLG FGDESPEPEA RGERLGRKVA PLATTEDSLA 
       550        560        570        580        590        600 
SIPFIDEPTS PSIDLQAKHV PASAVVSSAM NSAPVLGTSP SSPTFTFALS RHYSQDCSSI 
       610        620        630        640        650        660 
KAGRRSSYLL AITTERSKSC DDGLNTFRDE GRVLRRLPSR VPSLRVLRSF FTDGSLDSWG 
       670        680        690        700        710        720 
TSEDADAPSK RHSTSDLSDA TFSDIRREGW LYYKQILTKK GKKAGGGLRQ WKRVYAVLRA 
       730        740        750        760        770        780 
RSLSLSKERR EPGPAAAGAA AAGAGEDEAA PVCIGSCLVD ISYSETKRRH VFRLTTADFC 
       790        800        810        820        830        840 
EYLFQAEDRD DMLGWIRAIR ENSRAEGEDP GCANQALISK KLNDYRKVSH SSGPKADSSP 
       850        860        870        880        890        900 
KGSRGLGGLK SEFLKQTAVR GLRTQEQPPG SKEDSVAAPK TPWGINIIKK NKKAAPRAFG 
       910        920        930        940        950        960 
IRLEECQPAT ENQRVPLIVA ACCRIVEARG LESTGIYRVP GNNAVVSSLQ EQLNRGPSDI 
       970        980        990       1000       1010       1020 
NLQDERWQDL NVISSLLKAF FRKLPEPLFT DDKYNDFIEA NRIEDSRERM KTLRKLIRDL 
      1030       1040       1050       1060       1070       1080 
PGHYYETLKF LVGHLKTIAD HSEKNKMEPR NLALVFGPTL VRTSEDNMTD MVTHMPDRYK 
      1090       1100       1110       1120       1130       1140 
IVETLIQHSD WFFSDDEDKG ERTPVDDKEP QSVPNIEYLL PNIGRTVPPS DPGSDSTTCS 
      1150       1160       1170       1180       1190       1200 
SAKSKGSWVP KKEPYAREML AISFISAVNR KRKKRREARG LGSSTDDDSE QEAHKAAVGT 
      1210       1220       1230       1240       1250       1260 
QEPPEGQLPG PAAEEAPGRL SPPTAPDERP AADTRSIVSG YSTLSTMDRS VCSGTGGRRA 
      1270       1280       1290       1300       1310       1320 
GAGDEADDER SELSHVETDT EGGAGPGGRL SRRPSFSSHH LMPCDTLARR RLSRSRAEAE 
      1330       1340       1350       1360       1370       1380 
GPGAGTARAC PRGPEPPGSA SSSSQESLRP PAAAPALGSR PSRVEALRLR LRGTADDMLA 
      1390       1400       1410       1420       1430       1440 
VRLRRPLSPE TRRRRSSWRR HTVVVQSPLT DLNFNEWKEL GGGGPQESVG VRPHSDNKDS 
      1450       1460       1470       1480    
GLSSLESTKA RASSAASLPS GDLGALQGLP QRRSAAARLH QCL



Filter Information:


(REFRESH)

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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q69ZH9-1-unknown MNGVAF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q69ZH9-1159-unknown MLAISF... 1159 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87645

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LHQCL 1483 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LHQCL 1483 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83263

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)