TopFIND 4.0

Q69ZL1: FYVE, RhoGEF and PH domain-containing protein 6

General Information

Protein names
- FYVE, RhoGEF and PH domain-containing protein 6
Gene names Fgd6
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q69ZL1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTSAAELKKP PLAPKPKLVG TNNKPPPPPI APKPDIGSAS VPRLTKKTKP AIAPKPKVPT 
        70         80         90        100        110        120 
NSVVQDIKHP PSKKPTLNLE EREPELPEST GKSNCKDVRD PHSDYILPTC SCSSGCIHEP 
       130        140        150        160        170        180 
RTRETQCVEQ LVLEPLGMKE NLENSKNGES SKRGSSWDSS SEKCRGQSGV VLKASILEEK 
       190        200        210        220        230        240 
LKEVLTQQRS PCGSPGRHRA PKKPEMNGDH SCTRQIRIEF ADVSSSLTGF EKVPAHHNCH 
       250        260        270        280        290        300 
PQLPRDESQT LKTCQDGSAE SRGHTDSCEP ENKRVASDGI SQKTEVKGLG PLEIHLLPYT 
       310        320        330        340        350        360 
SKFPTPKPRK THAAARLRRQ KHVDTPGEST EEPGNSNNGS SCLLEDYCLK NNKVSVLRQN 
       370        380        390        400        410        420 
ALYNQGPVDE VRPANQRALT GDSNSGGQDS VGSQKAVQQQ TPSLDTDSSL TSDSSGSGVS 
       430        440        450        460        470        480 
PAVDKETTYT QCSTQPLSLP KQVTSACTDQ PPATCNPEVS APPIQKESSS SRIIPKKPQR 
       490        500        510        520        530        540 
HSLPAAGVLK KAASEELVEK SSSGKETNVE KGLHRNYLHH PGPPNHGASA SPFDMPNPTS 
       550        560        570        580        590        600 
EKPVWKLPHP ILPFSGSPEA LKRVTLSLNN EPSVSLTKPR AKSLSAVDAD RCNKPCKDPP 
       610        620        630        640        650        660 
KKTSFKKLIN VKLSIGFIKS DFQKIRSKSC QHGDVSAGHP LAREPKGLES DWQGLATGEE 
       670        680        690        700        710        720 
KRSKPTKAHS AENCSLESQK VKSWGQSSAV NGQRAESLDD RILSRHTSCT GDFGPEYENV 
       730        740        750        760        770        780 
RHYEEIPEYE NLPFVMAGRN TPDLGWQNSS SVEDTDASLY EVEEPYNAPD GQLQLDPRHQ 
       790        800        810        820        830        840 
PCSSGTSQEG KDALHLGLSD LPSDEEVINS SDEDDVSSES SKGEPDPLED KQDEDAGMKS 
       850        860        870        880        890        900 
KVHHIAKEIM SSEKVFVDVL KLLHIDFRGA VAHASRQLGK PVIEDRILNQ ILYYLPQLYE 
       910        920        930        940        950        960 
LNRDLLKELE ERMLTWTEQQ RIADIFVKKG PYLKMYSTYI KEFDKNVALL DEQCKKNPGF 
       970        980        990       1000       1010       1020 
AAVVREFEMS PRCANLALKH YLLKPVQRIP QYRLLLTDYL KNLLEDSVDH RDTQDALAVV 
      1030       1040       1050       1060       1070       1080 
IEVANHANDT MKQGDNFQKL MQIQYSLSGH HEIVQPGRVF LKEGTLMKLS RKVMQPRMFF 
      1090       1100       1110       1120       1130       1140 
LFNDALLYTT PMQSGMYKLN NMLSLAGMKV RKPTQEAYQN ELKIESVERS FILSASSAAE 
      1150       1160       1170       1180       1190       1200 
RDDWLEAISS SIEEYAKKRI TFCPSRSLDE DSERKEEVSP LGAKAPIWIP DTRATMCMIC 
      1210       1220       1230       1240       1250       1260 
TSEFTLTWRR HHCRACGKIV CQACSSNKYG LDYLKGQLAR VCEHCFQELQ KLDHQLSPRV 
      1270       1280       1290       1300       1310       1320 
GSPGNHKSPS SALSSVLHSI PSGRKQKKIP AALKEVSANT EDSTMSGYLY RSKGSKKPWK 
      1330       1340       1350       1360       1370       1380 
HLWFVIKNKV LYTYAASEDV AALESQPLLG FTVTLVKDEN SESKVFQLLH KGMVFYVFKA 
      1390    
DDAHSTQRWI DAFQEGTVL

Isoforms

- Isoform 2 of FYVE, RhoGEF and PH domain-containing protein 6

Sequence View

        10         20         30         40         50         60 
MTSAAELKKP PLAPKPKLVG TNNKPPPPPI APKPDIGSAS VPRLTKKTKP AIAPKPKVPT 
        70         80         90        100        110        120 
NSVVQDIKHP PSKKPTLNLE EREPELPEST GKSNCKDVRD PHSDYILPTC SCSSGCIHEP 
       130        140        150        160        170        180 
RTRETQCVEQ LVLEPLGMKE NLENSKNGES SKRGSSWDSS SEKCRGQSGV VLKASILEEK 
       190        200        210        220        230        240 
LKEVLTQQRS PCGSPGRHRA PKKPEMNGDH SCTRQIRIEF ADVSSSLTGF EKVPAHHNCH 
       250        260        270        280        290        300 
PQLPRDESQT LKTCQDGSAE SRGHTDSCEP ENKRVASDGI SQKTEVKGLG PLEIHLLPYT 
       310        320        330        340        350        360 
SKFPTPKPRK THAAARLRRQ KHVDTPGEST EEPGNSNNGS SCLLEDYCLK NNKVSVLRQN 
       370        380        390        400        410        420 
ALYNQGPVDE VRPANQRALT GDSNSGGQDS VGSQKAVQQQ TPSLDTDSSL TSDSSGSGVS 
       430        440        450        460        470        480 
PAVDKETTYT QCSTQPLSLP KQVTSACTDQ PPATCNPEVS APPIQKESSS SRIIPKKPQR 
       490        500        510        520        530        540 
HSLPAAGVLK KAASEELVEK SSSGKETNVE KGLHRNYLHH PGPPNHGASA SPFDMPNPTS 
       550        560        570        580        590        600 
EKPVWKLPHP ILPFSGSPEA LKRVTLSLNN EPSVSLTKPR AKSLSAVDAD RCNKPCKDPP 
       610        620        630        640        650        660 
KKTSFKKLIN VKLSIGFIKS DFQKIRSKSC QHGDVSAGHP LAREPKGLES DWQGLATGEE 
       670        680        690        700        710        720 
KRSKPTKAHS AENCSLESQK VKSWGQSSAV NGQRAESLDD RILSRHTSCT GDFGPEYENV 
       730        740        750        760        770        780 
RHYEEIPEYE NLPFVMAGRN TPDLGWQNSS SVEDTDASLY EVEEPYNAPD GQLQLDPRHQ 
       790        800        810        820        830        840 
PCSSGTSQEG KDALHLGLSD LPSDEEVINS SDEDDVSSES SKGEPDPLED KQDEDAGMKS 
       850        860        870        880        890        900 
KVHHIAKEIM SSEKVFVDVL KLLHIDFRGA VAHASRQLGK PVIEDRILNQ ILYYLPQLYE 
       910        920        930        940        950        960 
LNRDLLKELE ERMLTWTEQQ RIADIFVKKG PYLKMYSTYI KEFDKNVALL DEQCKKNPGF 
       970        980        990       1000       1010       1020 
AAVVREFEMS PRCANLALKH YLLKPVQRIP QYRLLLTDYL KNLLEDSVDH RDTQDALAVV 
      1030       1040       1050       1060       1070       1080 
IEVANHANDT MKQGDNFQKL MQIQYSLSGH HEIVQPGRVF LKEGTLMKLS RKVMQPRMFF 
      1090       1100       1110       1120       1130       1140 
LFNDALLYTT PMQSGMYKLN NMLSLAGMKV RKPTQEAYQN ELKIESVERS FILSASSAAE 
      1150       1160       1170       1180       1190       1200 
RDDWLEAISS SIEEYAKKRI TFCPSRSLDE DSERKEEVSP LGAKAPIWIP DTRATMCMIC 
      1210       1220       1230       1240       1250       1260 
TSEFTLTWRR HHCRACGKIV CQACSSNKYG LDYLKGQLAR VCEHCFQELQ KLDHQLSPRV 
      1270       1280       1290       1300       1310       1320 
GSPGNHKSPS SALSSVLHSI PSGRKQKKIP AALKEVSANT EDSTMSGYLY RSKGSKKPWK 
      1330       1340       1350       1360       1370       1380 
HLWFVIKNKV LYTYAASEDV AALESQPLLG FTVTLVKDEN SESKVFQLLH KGMVFYVFKA 
      1390    
DDAHSTQRWI DAFQEGTVL



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q69ZL1-1-unknown MTSAAE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q69ZL1-935-unknown MYSTYI... 935 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75076

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EGTVL 1399 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EGTVL 1399 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70694

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)