Q6AI08: HEAT repeat-containing protein 6
| Protein names | - HEAT repeat-containing protein 6 - Amplified in breast cancer protein 1 |
|---|---|
| Gene names | HEATR6 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q6AI08 |
2
N-termini
3
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAAVQVVGSW PSVQPREAPR EAIPERGNGF RLLSARLCAL RPDDSSSART EIHLLFDQLI
70 80 90 100 110 120
SENYSEGSGV APEDVSALLV QACRLVPLNQ NHLVSKVSQL IHHLLNRLQV IVDEQHLDFL
130 140 150 160 170 180
LAYTISAIHQ CSSWTHREIL QALAALVYCN GSKCQKYLPE LLGNTGLLMK LSDLAQSDPE
190 200 210 220 230 240
VRRAAVHCMA NLCLSVPGQP YLEEPYQNVC FQAFLTILQS PKSSDMDDIT FCMLLQNALK
250 260 270 280 290 300
GIQSLLNGGR MKLTQTDELG ALLAVLKKFM FHGLPGLNIE MPTVLYPTPL PQYDGRTPIK
310 320 330 340 350 360
PQQSESSASR PTLNKKKKSK VKPKKIQQGE EEEKESSGEI EAAPVTGTGR VNLHEGNTWC
370 380 390 400 410 420
PSSLGVQSLP LDGSGAAEKD GVSSSFSSSS WKRVSSSESD FSDAEGGMQS KMRSYQAKVR
430 440 450 460 470 480
QGALVCFLST IKSIEKKVLY GYWSAFIPDT PELGSPQSVS LMTLTLKDPS PKTRACALQV
490 500 510 520 530 540
LSAILEGSKQ FLSVAEDTSD HRRAFTPFSV MIACSIRELH RCLLLALVAE SSSQTVTQII
550 560 570 580 590 600
KCLANLVSNA PYDRLKLSLL TKVWNQIKPY IRHKDVNVRV SSLTLLGAIV STHAPLPEVQ
610 620 630 640 650 660
LLLQQPCSSG LGNSNSATPH LSPPDWWKKA PAGPSLEETS VSSPKGSSEP CWLIRLCISI
670 680 690 700 710 720
VVLPKEDSCS GSDAGSAAGS TYEPSPMRLE ALQVLTLLAR GYFSMTQAYL MELGEVICKC
730 740 750 760 770 780
MGEADPSIQL HGAKLLEELG TGLIQQYKPD STAAPDQRAP VFLVVMFWTM MLNGPLPRAL
790 800 810 820 830 840
QNSEHPTLQA SACDALSSIL PEAFSNLPND RQMLCITVLL GLNDSKNRLV KAATSRALGV
850 860 870 880 890 900
YVLFPCLRQD VIFVADAANA ILMSLEDKSL NVRAKAAWSL GNLTDTLIVN METPDPSFQE
910 920 930 940 950 960
EFSGLLLLKM LRSAIEASKD KDKVKSNAVR ALGNLLHFLQ PSHIEKPTFA EIIEESIQAL
970 980 990 1000 1010 1020
ISTVLTEAAM KVRWNACYAM GNVFKNPALP LGTAPWTSQA YNALTSVVTS CKNFKVRIRS
1030 1040 1050 1060 1070 1080
AAALSVPGKR EQYGSVDQYA RIWNALVTAL QKSEDTIDFL EFKYCVSLRT QICQALIHLL
1090 1100 1110 1120 1130 1140
SLASASDLPC MKETLELSGN MVQSYILQFL KSGAEGDDTG APHSPQERDQ MVRMALKHMG
1150 1160 1170 1180
SIQAPTGDTA RRAIMGFLEE ILAVCFDSSG SQGALPGLTN Q
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q6AI08-1-unknown | MAAVQV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q6AI08-381- | GVSSSF... | 381 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
| Q6AI08-381- | GVSSSF... | 381 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GLLMKL | 170 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000468810 | |||
| ...DDITFC | 231 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000465429 | |||
| ...GLTNQ | 1181 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|