TopFIND 4.0

Q6AXQ4: Myotubularin

General Information

Protein names
- Myotubularin
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
- 3.1.3.95 {ECO:0000250|UniProtKB:Q13496}
- Phosphatidylinositol-3-phosphate phosphatase
- 3.1.3.64 {ECO:0000250|UniProtKB:Q13496}
Gene names Mtm1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6AXQ4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASSSASDCD AHPVERESMR KVSQDGVRQD MSKSGPRLPG ESAITDKEVI YICPFSGPVK 
        70         80         90        100        110        120 
GRLYITNYRL YLRSLETDLA PILDVPLGVI SRIEKMGGVT SRGENSYGLD ITCKDLRNLR 
       130        140        150        160        170        180 
FALKQEGHSR RDIFDVLTRH AFPLAYNLPL FAFVNEEKFK VDGWAIYNPV EEYRRQGLPD 
       190        200        210        220        230        240 
RHWRISFVNQ RYELCDTYPA LLVVPYRASD DDLRRVATFR SRNRIPVLSW IHPENRAAIM 
       250        260        270        280        290        300 
RCSQPLVGVG GKRSRDDERY LDIIRETNKQ TSKLTIYDAR PGVNAVANKA TGGGYEGEDA 
       310        320        330        340        350        360 
YPHAELSFLD IHNIHVMRES LRRVRDIVYP HVEEAHWLSS LESTHWLEHI KLLLTGAIRV 
       370        380        390        400        410        420 
ADKVASGLSS VLVHCSDGWD RTAQLTTLAM LMLDGFYRSI EGFEILVQKE WISFGHKFSS 
       430        440        450        460        470        480 
RIGHGDKNHA DADRSPIFLQ FIDCVWQMTK QFPTAFEFNE CFLVAILDHL YSCRFGTFLL 
       490        500        510        520        530        540 
NCEAARERQR LAERTVSVWS LINSNKDEFT NPFYARESNR VIYPVTSVRH LELWVNYYIR 
       550        560        570        580        590        600 
WNPRIRQQPH PMEQRYNELL ALRDDYIKKL EELQLATPTK LTDSSTPPSG SAQIAPRMQT 
   
HF

Isoforms

- Isoform 2 of Myotubularin

Sequence View

        10         20         30         40         50         60 
MASSSASDCD AHPVERESMR KVSQDGVRQD MSKSGPRLPG ESAITDKEVI YICPFSGPVK 
        70         80         90        100        110        120 
GRLYITNYRL YLRSLETDLA PILDVPLGVI SRIEKMGGVT SRGENSYGLD ITCKDLRNLR 
       130        140        150        160        170        180 
FALKQEGHSR RDIFDVLTRH AFPLAYNLPL FAFVNEEKFK VDGWAIYNPV EEYRRQGLPD 
       190        200        210        220        230        240 
RHWRISFVNQ RYELCDTYPA LLVVPYRASD DDLRRVATFR SRNRIPVLSW IHPENRAAIM 
       250        260        270        280        290        300 
RCSQPLVGVG GKRSRDDERY LDIIRETNKQ TSKLTIYDAR PGVNAVANKA TGGGYEGEDA 
       310        320        330        340        350        360 
YPHAELSFLD IHNIHVMRES LRRVRDIVYP HVEEAHWLSS LESTHWLEHI KLLLTGAIRV 
       370        380        390        400        410        420 
ADKVASGLSS VLVHCSDGWD RTAQLTTLAM LMLDGFYRSI EGFEILVQKE WISFGHKFSS 
       430        440        450        460        470        480 
RIGHGDKNHA DADRSPIFLQ FIDCVWQMTK QFPTAFEFNE CFLVAILDHL YSCRFGTFLL 
       490        500        510        520        530        540 
NCEAARERQR LAERTVSVWS LINSNKDEFT NPFYARESNR VIYPVTSVRH LELWVNYYIR 
       550        560        570        580        590        600 
WNPRIRQQPH PMEQRYNELL ALRDDYIKKL EELQLATPTK LTDSSTPPSG SAQIAPRMQT 
   
HF



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6AXQ4-1-unknown MASSSA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6AXQ4-1-unknown MASSSA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193014

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MQTHF 602 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...MQTHF 602 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152960

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)