Q6DTY7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

General Information

Protein names	- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 - 6PF-2-K/Fru-2,6-P2ase 4 - PFK/FBPase 4 - 6PF-2-K/Fru-2,6-P2ase testis-type isozyme - 6-phosphofructo-2-kinase - 2.7.1.105 - Fructose-2,6-bisphosphatase - 3.1.3.46
Gene names	Pfkfb4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6DTY7

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 - Isoform 3 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 - Isoform 4 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 - Isoform 5 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 - Isoform 6 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

Sequence View

        10         20         30         40         50         60
MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT
        70         80         90        100        110        120
RYLNWIGVPT REFNVGQYRR DIVKTYKSFE FFLPDNEEGL KIRKQCALAA LSDVRKFLSE
       130        140        150        160        170        180
EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVVAANIV QVKLGSPDYV
       190        200        210        220        230        240
NRDSDEATED FMRRIECYEN SYESLDEDLD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY
       250        260        270        280        290        300
YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW
       310        320        330        340        350        360
TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY
       370        380        390        400        410        420
PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV
       430        440        450        460
LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ         10         20         30         40         50         60
MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT
        70         80         90        100        110        120
RYLNWIGVPT REFNVGQYRR DIVKTYKSFE FFLPDNEEGL KIRKQCALAA LSDVRKFLSE
       130        140        150        160        170        180
EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVVAANIV QVKLGSPDYV
       190        200        210        220        230        240
NRDSDEATED FMRRIECYEN SYESLDEDLD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY
       250        260        270        280        290        300
YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW
       310        320        330        340        350        360
TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY
       370        380        390        400        410        420
PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV
       430        440        450        460
LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ         10         20         30         40         50         60
MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT
        70         80         90        100        110        120
RYLNWIGVPT REFNVGQYRR DIVKTYKSFE FFLPDNEEGL KIRKQCALAA LSDVRKFLSE
       130        140        150        160        170        180
EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVVAANIV QVKLGSPDYV
       190        200        210        220        230        240
NRDSDEATED FMRRIECYEN SYESLDEDLD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY
       250        260        270        280        290        300
YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW
       310        320        330        340        350        360
TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY
       370        380        390        400        410        420
PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV
       430        440        450        460
LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ         10         20         30         40         50         60
MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT
        70         80         90        100        110        120
RYLNWIGVPT REFNVGQYRR DIVKTYKSFE FFLPDNEEGL KIRKQCALAA LSDVRKFLSE
       130        140        150        160        170        180
EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVVAANIV QVKLGSPDYV
       190        200        210        220        230        240
NRDSDEATED FMRRIECYEN SYESLDEDLD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY
       250        260        270        280        290        300
YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW
       310        320        330        340        350        360
TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY
       370        380        390        400        410        420
PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV
       430        440        450        460
LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ         10         20         30         40         50         60
MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT
        70         80         90        100        110        120
RYLNWIGVPT REFNVGQYRR DIVKTYKSFE FFLPDNEEGL KIRKQCALAA LSDVRKFLSE
       130        140        150        160        170        180
EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVVAANIV QVKLGSPDYV
       190        200        210        220        230        240
NRDSDEATED FMRRIECYEN SYESLDEDLD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY
       250        260        270        280        290        300
YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW
       310        320        330        340        350        360
TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY
       370        380        390        400        410        420
PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV
       430        440        450        460
LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6DTY7-1-unknown	MASPRE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6DTY7-1-unknown	MASPRE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74590
Q6DTY7-1-unknown	MASPRE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74591
Q6DTY7-1-unknown	MASPRE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74592
Q6DTY7-35-unknown	MTNCPT...	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74593
Q6DTY7-35-unknown	MTNCPT...	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101379
Q6DTY7-35-unknown	MTNCPT...	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101380
Q6DTY7-219-unknown	MDVGQS...	219	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74589
Q6DTY7-219-unknown	MDVGQS...	219	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101152
Q6DTY7-219-unknown	MDVGQS...	219	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101153
Q6DTY7-219-unknown	MDVGQS...	219	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101154

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VPAHQ	469	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VPAHQ	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70207
...VPAHQ	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70211
...VPAHQ	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70210

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)