Q6HA09: Astacin-like metalloendopeptidase

General Information

Protein names	- Astacin-like metalloendopeptidase - 3.4.-.- - Oocyte astacin - Ovastacin - Sperm acrosomal SLLP1-binding protein
Gene names	Astl
Organism	Mus musculus
Protease Family
Protease ID	M12.245
Chromosome location
UniProt ID	Q6HA09

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Astacin-like metalloendopeptidase - Isoform 3 of Astacin-like metalloendopeptidase - Isoform 4 of Astacin-like metalloendopeptidase - Isoform 5 of Astacin-like metalloendopeptidase - Isoform 6 of Astacin-like metalloendopeptidase

Sequence View

        10         20         30         40         50         60
MGIMGSLWPW ILTMLSLLGL SMGAPSASRC SGVCSTSVPE GFTPEGSPVF QDKDIPAINQ
        70         80         90        100        110        120
GLISEETPES SFLVEGDIIR PSPFRLLSVT NNKWPKGVGG FVEIPFLLSR KYDELSRRVI
       130        140        150        160        170        180
MDAFAEFERF TCIRFVAYHG QRDFVSILPM AGCFSGVGRS GGMQVVSLAP TCLRKGRGIV
       190        200        210        220        230        240
LHELMHVLGF WHEHSRADRD RYIQVNWNEI LPGFEINFIK SRSTNMLVPY DYSSVMHYGR
       250        260        270        280        290        300
FAFSWRGQPT IIPLWTSSVH IGQRWNLSTS DITRVCRLYN CSRSVPDSHG RGFEAQSDGS
       310        320        330        340        350        360
SLTPASISRL QRLLEALSEE SGSSAPSGSR TGGQSIAGLG NSQQGWEHPP QSTFSVGALA
       370        380        390        400        410        420
RPPQMLADAS KSGPGAGADS LSLEQFQLAQ APTVPLALFP EARDKPAPIQ DAFERLAPLP
       430
GGCAPGSHIR EVPRD         10         20         30         40         50         60
MGIMGSLWPW ILTMLSLLGL SMGAPSASRC SGVCSTSVPE GFTPEGSPVF QDKDIPAINQ
        70         80         90        100        110        120
GLISEETPES SFLVEGDIIR PSPFRLLSVT NNKWPKGVGG FVEIPFLLSR KYDELSRRVI
       130        140        150        160        170        180
MDAFAEFERF TCIRFVAYHG QRDFVSILPM AGCFSGVGRS GGMQVVSLAP TCLRKGRGIV
       190        200        210        220        230        240
LHELMHVLGF WHEHSRADRD RYIQVNWNEI LPGFEINFIK SRSTNMLVPY DYSSVMHYGR
       250        260        270        280        290        300
FAFSWRGQPT IIPLWTSSVH IGQRWNLSTS DITRVCRLYN CSRSVPDSHG RGFEAQSDGS
       310        320        330        340        350        360
SLTPASISRL QRLLEALSEE SGSSAPSGSR TGGQSIAGLG NSQQGWEHPP QSTFSVGALA
       370        380        390        400        410        420
RPPQMLADAS KSGPGAGADS LSLEQFQLAQ APTVPLALFP EARDKPAPIQ DAFERLAPLP
       430
GGCAPGSHIR EVPRD         10         20         30         40         50         60
MGIMGSLWPW ILTMLSLLGL SMGAPSASRC SGVCSTSVPE GFTPEGSPVF QDKDIPAINQ
        70         80         90        100        110        120
GLISEETPES SFLVEGDIIR PSPFRLLSVT NNKWPKGVGG FVEIPFLLSR KYDELSRRVI
       130        140        150        160        170        180
MDAFAEFERF TCIRFVAYHG QRDFVSILPM AGCFSGVGRS GGMQVVSLAP TCLRKGRGIV
       190        200        210        220        230        240
LHELMHVLGF WHEHSRADRD RYIQVNWNEI LPGFEINFIK SRSTNMLVPY DYSSVMHYGR
       250        260        270        280        290        300
FAFSWRGQPT IIPLWTSSVH IGQRWNLSTS DITRVCRLYN CSRSVPDSHG RGFEAQSDGS
       310        320        330        340        350        360
SLTPASISRL QRLLEALSEE SGSSAPSGSR TGGQSIAGLG NSQQGWEHPP QSTFSVGALA
       370        380        390        400        410        420
RPPQMLADAS KSGPGAGADS LSLEQFQLAQ APTVPLALFP EARDKPAPIQ DAFERLAPLP
       430
GGCAPGSHIR EVPRD         10         20         30         40         50         60
MGIMGSLWPW ILTMLSLLGL SMGAPSASRC SGVCSTSVPE GFTPEGSPVF QDKDIPAINQ
        70         80         90        100        110        120
GLISEETPES SFLVEGDIIR PSPFRLLSVT NNKWPKGVGG FVEIPFLLSR KYDELSRRVI
       130        140        150        160        170        180
MDAFAEFERF TCIRFVAYHG QRDFVSILPM AGCFSGVGRS GGMQVVSLAP TCLRKGRGIV
       190        200        210        220        230        240
LHELMHVLGF WHEHSRADRD RYIQVNWNEI LPGFEINFIK SRSTNMLVPY DYSSVMHYGR
       250        260        270        280        290        300
FAFSWRGQPT IIPLWTSSVH IGQRWNLSTS DITRVCRLYN CSRSVPDSHG RGFEAQSDGS
       310        320        330        340        350        360
SLTPASISRL QRLLEALSEE SGSSAPSGSR TGGQSIAGLG NSQQGWEHPP QSTFSVGALA
       370        380        390        400        410        420
RPPQMLADAS KSGPGAGADS LSLEQFQLAQ APTVPLALFP EARDKPAPIQ DAFERLAPLP
       430
GGCAPGSHIR EVPRD         10         20         30         40         50         60
MGIMGSLWPW ILTMLSLLGL SMGAPSASRC SGVCSTSVPE GFTPEGSPVF QDKDIPAINQ
        70         80         90        100        110        120
GLISEETPES SFLVEGDIIR PSPFRLLSVT NNKWPKGVGG FVEIPFLLSR KYDELSRRVI
       130        140        150        160        170        180
MDAFAEFERF TCIRFVAYHG QRDFVSILPM AGCFSGVGRS GGMQVVSLAP TCLRKGRGIV
       190        200        210        220        230        240
LHELMHVLGF WHEHSRADRD RYIQVNWNEI LPGFEINFIK SRSTNMLVPY DYSSVMHYGR
       250        260        270        280        290        300
FAFSWRGQPT IIPLWTSSVH IGQRWNLSTS DITRVCRLYN CSRSVPDSHG RGFEAQSDGS
       310        320        330        340        350        360
SLTPASISRL QRLLEALSEE SGSSAPSGSR TGGQSIAGLG NSQQGWEHPP QSTFSVGALA
       370        380        390        400        410        420
RPPQMLADAS KSGPGAGADS LSLEQFQLAQ APTVPLALFP EARDKPAPIQ DAFERLAPLP
       430
GGCAPGSHIR EVPRD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6HA09-1-unknown	MGIMGS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67696
Q6HA09-1-unknown	MGIMGS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67697
Q6HA09-22-unknown	MGAPSA...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67695
Q6HA09-22-unknown	MGAPSA...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67698
Q6HA09-22-unknown	MGAPSA...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67699
Q6HA09-22-unknown	MGAPSA...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102171
Q6HA09-22-unknown	MGAPSA...	22	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102172
Q6HA09-24-unknown	APSASR...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6HA09-24-unknown	APSASR...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113579
Q6HA09-24-unknown	APSASR...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113580
Q6HA09-24-unknown	APSASR...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113583
Q6HA09-24-unknown	APSASR...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113581
Q6HA09-24-unknown	APSASR...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113582

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EVPRD	435	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EVPRD	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63317
...EVPRD	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63316
...EVPRD	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63315
...EVPRD	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63314
...EVPRD	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63313

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)