Q6IA69: Glutamine-dependent NAD(+) synthetase

General Information

Protein names	- Glutamine-dependent NAD(+) synthetase - 6.3.5.1 {ECO:0000269\|PubMed:12547821} - NAD(+) synthase glutamine-hydrolyzing] - NAD(+) synthetase
Gene names	NADSYN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6IA69

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGRKVTVATC ALNQWALDFE GNLQRILKSI EIAKNRGARY RLGPELEICG YGCWDHYYES
        70         80         90        100        110        120
DTLLHSFQVL AALVESPVTQ DIICDVGMPV MHRNVRYNCR VIFLNRKILL IRPKMALANE
       130        140        150        160        170        180
GNYRELRWFT PWSRSRHTEE YFLPRMIQDL TKQETVPFGD AVLVTWDTCI GSEICEELWT
       190        200        210        220        230        240
PHSPHIDMGL DGVEIITNAS GSHQVLRKAN TRVDLVTMVT SKNGGIYLLA NQKGCDGDRL
       250        260        270        280        290        300
YYDGCAMIAM NGSVFAQGSQ FSLDDVEVLT ATLDLEDVRS YRAEISSRNL AASRASPYPR
       310        320        330        340        350        360
VKVDFALSCH EDLLAPISEP IEWKYHSPEE EISLGPACWL WDFLRRSQQA GFLLPLSGGV
       370        380        390        400        410        420
DSAATACLIY SMCCQVCEAV RSGNEEVLAD VRTIVNQISY TPQDPRDLCG RILTTCYMAS
       430        440        450        460        470        480
KNSSQETCTR ARELAQQIGS HHISLNIDPA VKAVMGIFSL VTGKSPLFAA HGGSSRENLA
       490        500        510        520        530        540
LQNVQARIRM VLAYLFAQLS LWSRGVHGGL LVLGSANVDE SLLGYLTKYD CSSADINPIG
       550        560        570        580        590        600
GISKTDLRAF VQFCIQRFQL PALQSILLAP ATAELEPLAD GQVSQTDEED MGMTYAELSV
       610        620        630        640        650        660
YGKLRKVAKM GPYSMFCKLL GMWRHICTPR QVADKVKRFF SKYSMNRHKM TTLTPAYHAE
       670        680        690        700
NYSPEDNRFD LRPFLYNTSW PWQFRCIENQ VLQLERAEPQ SLDGVD

Isoforms

- Isoform 2 of Glutamine-dependent NAD(+) synthetase

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6IA69-1-unknown	MGRKVT...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6IA69-372-unknown	MCCQVC...	372	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437172
Q6IA69-372-unknown	MCCQVC...	372	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431820

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ANVDES	520	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000437172
...LDGVD	706	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LDGVD	706		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LDGVD	706		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LDGVD	706		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LDGVD	706		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)