TopFIND 4.0

Q6IC98: GRAM domain-containing protein 4 {ECO:0000305}

General Information

Protein names
- GRAM domain-containing protein 4 {ECO:0000305}
- Death-inducing protein
Gene names GRAMD4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6IC98

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLRRLDKIRF RGHKRDDFLD LAESPNASDT ECSDEIPLKV PRTSPRDSEE LRDPAGPGTL 
        70         80         90        100        110        120 
IMATGVQDFN RTEFDRLNEI KGHLEIALLE KHFLQEELRK LREETNAEML RQELDRERQR 
       130        140        150        160        170        180 
RMELEQKVQE VLKARTEEQM AQQPPKGQAQ ASNGAERRSQ GLSSRLQKWF YERFGEYVED 
       190        200        210        220        230        240 
FRFQPEENTV ETEEPLSARR LTENMRRLKR GAKPVTNFVK NLSALSDWYS VYTSAIAFTV 
       250        260        270        280        290        300 
YMNAVWHGWA IPLFLFLAIL RLSLNYLIAR GWRIQWSIVP EVSEPVEPPK EDLTVSEKFQ 
       310        320        330        340        350        360 
LVLDVAQKAQ NLFGKMADIL EKIKNLFMWV QPEITQKLYV ALWAAFLASC FFPYRLVGLA 
       370        380        390        400        410        420 
VGLYAGIKFF LIDFIFKRCP RLRAKYDTPY IIWRSLPTDP QLKERSSAAV SRRLQTTSSR 
       430        440        450        460        470        480 
SYVPSAPAGL GKEEDAGRFH STKKGNFHEI FNLTENERPL AVCENGWRCC LINRDRKMPT 
       490        500        510        520        530        540 
DYIRNGVLYV TENYLCFESS KSGSSKRNKV IKLVDITDIQ KYKVLSVLPG SGMGIAVSTP 
       550        560        570    
STQKPLVFGA MVHRDEAFET ILSQYIKITS AAASGGDS

Isoforms

- Isoform 2 of GRAM domain-containing protein 4

Sequence View

        10         20         30         40         50         60 
MLRRLDKIRF RGHKRDDFLD LAESPNASDT ECSDEIPLKV PRTSPRDSEE LRDPAGPGTL 
        70         80         90        100        110        120 
IMATGVQDFN RTEFDRLNEI KGHLEIALLE KHFLQEELRK LREETNAEML RQELDRERQR 
       130        140        150        160        170        180 
RMELEQKVQE VLKARTEEQM AQQPPKGQAQ ASNGAERRSQ GLSSRLQKWF YERFGEYVED 
       190        200        210        220        230        240 
FRFQPEENTV ETEEPLSARR LTENMRRLKR GAKPVTNFVK NLSALSDWYS VYTSAIAFTV 
       250        260        270        280        290        300 
YMNAVWHGWA IPLFLFLAIL RLSLNYLIAR GWRIQWSIVP EVSEPVEPPK EDLTVSEKFQ 
       310        320        330        340        350        360 
LVLDVAQKAQ NLFGKMADIL EKIKNLFMWV QPEITQKLYV ALWAAFLASC FFPYRLVGLA 
       370        380        390        400        410        420 
VGLYAGIKFF LIDFIFKRCP RLRAKYDTPY IIWRSLPTDP QLKERSSAAV SRRLQTTSSR 
       430        440        450        460        470        480 
SYVPSAPAGL GKEEDAGRFH STKKGNFHEI FNLTENERPL AVCENGWRCC LINRDRKMPT 
       490        500        510        520        530        540 
DYIRNGVLYV TENYLCFESS KSGSSKRNKV IKLVDITDIQ KYKVLSVLPG SGMGIAVSTP 
       550        560        570    
STQKPLVFGA MVHRDEAFET ILSQYIKITS AAASGGDS



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6IC98-1-unknown MLRRLD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6IC98-478-unknown MPTDYI... 478 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76391

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SGGDS 578 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SGGDS 578 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt72009

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)