TopFIND 4.0

Q6IEE8: Schlafen family member 12-like

General Information

Protein names
- Schlafen family member 12-like
Gene names SLFN12L
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6IEE8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLARKEFLR GNGLAAGKMN ISIDLDTNYA ELVLNVGRVT LGENNRKKMK DCQLRKQQNE 
        70         80         90        100        110        120 
NVSRAVCALL NSGGGVIKAE VENKGYSYKK DGIGLDLENS FSNMLPFVPN FLDFMQNGNY 
       130        140        150        160        170        180 
FHIFVKSWSL ETSGPQIATL SSSLYKRDVT SAKVMNASAA LEFLKDMEKT GGRAYLRPEF 
       190        200        210        220        230        240 
PAKRACVDVQ EESNMEALAA DFFNRTELGY KEKLTFTEST HVEIKNFSTE KLLQRITEIL 
       250        260        270        280        290        300 
PQYVSAFANT DGGYLFVGLN EDKEVIGFKA EKSYLTKLEE VTKNSIGKLP VHHFCVEKGT 
       310        320        330        340        350        360 
INYLCKFLGV YDKGRLCGYV YALRVERFCC AVFAKKPDSW HVKDNRVKQL TEKEWIQFMV 
       370        380        390        400        410        420 
DSEPVCEELP SPASTSSPVS QSYPLREYIN FKIQPLRYHL PGLSEKITCA PKTFCRNLFS 
       430        440        450        460        470        480 
QHEGLKQLIC EEMGSVNKGS LIFSRSWSLD LGLQENHKVL CDALLISQDK PPVLYTFHMV 
       490        500        510        520        530        540 
QDEEFKDYST QTAQTLKQKL AKIGGYTKKV CVMTKIFYLS PEGKTSCQYD LNSQVIYPES 
       550        560        570        580    
YYWTTAQTMK DLEKALSNIL PKENQIFLFV CLFRFCLFVC WFVCFFLR

Isoforms

- Isoform 2 of Schlafen family member 12-like

Sequence View

        10         20         30         40         50         60 
MDLARKEFLR GNGLAAGKMN ISIDLDTNYA ELVLNVGRVT LGENNRKKMK DCQLRKQQNE 
        70         80         90        100        110        120 
NVSRAVCALL NSGGGVIKAE VENKGYSYKK DGIGLDLENS FSNMLPFVPN FLDFMQNGNY 
       130        140        150        160        170        180 
FHIFVKSWSL ETSGPQIATL SSSLYKRDVT SAKVMNASAA LEFLKDMEKT GGRAYLRPEF 
       190        200        210        220        230        240 
PAKRACVDVQ EESNMEALAA DFFNRTELGY KEKLTFTEST HVEIKNFSTE KLLQRITEIL 
       250        260        270        280        290        300 
PQYVSAFANT DGGYLFVGLN EDKEVIGFKA EKSYLTKLEE VTKNSIGKLP VHHFCVEKGT 
       310        320        330        340        350        360 
INYLCKFLGV YDKGRLCGYV YALRVERFCC AVFAKKPDSW HVKDNRVKQL TEKEWIQFMV 
       370        380        390        400        410        420 
DSEPVCEELP SPASTSSPVS QSYPLREYIN FKIQPLRYHL PGLSEKITCA PKTFCRNLFS 
       430        440        450        460        470        480 
QHEGLKQLIC EEMGSVNKGS LIFSRSWSLD LGLQENHKVL CDALLISQDK PPVLYTFHMV 
       490        500        510        520        530        540 
QDEEFKDYST QTAQTLKQKL AKIGGYTKKV CVMTKIFYLS PEGKTSCQYD LNSQVIYPES 
       550        560        570        580    
YYWTTAQTMK DLEKALSNIL PKENQIFLFV CLFRFCLFVC WFVCFFLR



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6IEE8-1-unknown MDLARK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CFFLR 588 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CFFLR 588 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt85736

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)