TopFIND 4.0

Q6IM78: DNA topoisomerase I, mitochondrial

General Information

Protein names
- DNA topoisomerase I, mitochondrial
- TOP1mt
- 5.6.2.2
Gene names Top1mt
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q6IM78

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLLLWLRALC RRFQHVPRRV PSRQVSRGSK ASRAGWGETS KSSVKWKQLE HKGPCFAPAY 
        70         80         90        100        110        120 
EPLPDGVRFF YDGKPVRLSL AAEEVATFYG KMLHLECTTK EVFRRNFFSD WQKEMTAEER 
       130        140        150        160        170        180 
KLITHLDKCD FSEIHRHFME RAEARRTLPR EQKQKLKEEA EKLQQEFGYC ILDGHREKIG 
       190        200        210        220        230        240 
NFKTEPPGLF RGRGDHPKMG MLKRRVMPED VVINCSRDSK IPEPPAGHQW KEVRSDNTVM 
       250        260        270        280        290        300 
WLAAWVENIQ NSFKYIILNP SSKPKGEMDW QKYEVARRLK GVVDKIRAQY QADWKSPEMK 
       310        320        330        340        350        360 
KRQLAVALYF IDKLALRTGN EKEEGETADT VGCCSLRVEH VRLHTPADGQ EHVVELDFLG 
       370        380        390        400        410        420 
KDSIRYKNHV TVEKLVFQNL QHFMEDKDPR DDLFDALTTS SLNKHLQDLM EGLTAKVFRT 
       430        440        450        460        470        480 
YNASITLQEQ LRVLTRAEDS LTCKVLAYNR ANRAVAVLCN HQRAIPKTFE ESMQTLQKKI 
       490        500        510        520        530        540 
ETKKAQVAEA QVELQKAETD LRMRGDSKSK SFLQKQQRLL KLEEQLARLC TKATDKEENK 
       550        560        570        580        590    
QVALGTAKLN YLDPRISIAW CKRFGVPVEK IYNKTQRERF AWAFNQAGED FEF

Isoforms



Sequence View



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Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6IM78-44-unknown VKWKQL... 44 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EDFEF 593 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)