TopFIND 4.0

Q6ISB3: Grainyhead-like protein 2 homolog

General Information

Protein names
- Grainyhead-like protein 2 homolog
- Brother of mammalian grainyhead
- Transcription factor CP2-like 3
Gene names GRHL2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6ISB3

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQESDNNKR LVALVPMPSD PPFNTRRAYT SEDEAWKSYL ENPLTAATKA MMSINGDEDS 
        70         80         90        100        110        120 
AAALGLLYDY YKVPRDKRLL SVSKASDSQE DQEKRNCLGT SEAQSNLSGG ENRVQVLKTV 
       130        140        150        160        170        180 
PVNLSLNQDH LENSKREQYS ISFPESSAII PVSGITVVKA EDFTPVFMAP PVHYPRGDGE 
       190        200        210        220        230        240 
EQRVVIFEQT QYDVPSLATH SAYLKDDQRS TPDSTYSESF KDAATEKFRS ASVGAEEYMY 
       250        260        270        280        290        300 
DQTSSGTFQY TLEATKSLRQ KQGEGPMTYL NKGQFYAITL SETGDNKCFR HPISKVRSVV 
       310        320        330        340        350        360 
MVVFSEDKNR DEQLKYWKYW HSRQHTAKQR VLDIADYKES FNTIGNIEEI AYNAVSFTWD 
       370        380        390        400        410        420 
VNEEAKIFIT VNCLSTDFSS QKGVKGLPLM IQIDTYSYNN RSNKPIHRAY CQIKVFCDKG 
       430        440        450        460        470        480 
AERKIRDEER KQNRKKGKGQ ASQTQCNSSS DGKLAAIPLQ KKSDITYFKT MPDLHSQPVL 
       490        500        510        520        530        540 
FIPDVHFANL QRTGQVYYNT DDEREGGSVL VKRMFRPMEE EFGPVPSKQM KEEGTKRVLL 
       550        560        570        580        590        600 
YVRKETDDVF DALMLKSPTV KGLMEAISEK YGLPVEKIAK LYKKSKKGIL VNMDDNIIEH 
       610        620    
YSNEDTFILN MESMVEGFKV TLMEI

Isoforms

- Isoform 2 of Grainyhead-like protein 2 homolog

Sequence View

        10         20         30         40         50         60 
MSQESDNNKR LVALVPMPSD PPFNTRRAYT SEDEAWKSYL ENPLTAATKA MMSINGDEDS 
        70         80         90        100        110        120 
AAALGLLYDY YKVPRDKRLL SVSKASDSQE DQEKRNCLGT SEAQSNLSGG ENRVQVLKTV 
       130        140        150        160        170        180 
PVNLSLNQDH LENSKREQYS ISFPESSAII PVSGITVVKA EDFTPVFMAP PVHYPRGDGE 
       190        200        210        220        230        240 
EQRVVIFEQT QYDVPSLATH SAYLKDDQRS TPDSTYSESF KDAATEKFRS ASVGAEEYMY 
       250        260        270        280        290        300 
DQTSSGTFQY TLEATKSLRQ KQGEGPMTYL NKGQFYAITL SETGDNKCFR HPISKVRSVV 
       310        320        330        340        350        360 
MVVFSEDKNR DEQLKYWKYW HSRQHTAKQR VLDIADYKES FNTIGNIEEI AYNAVSFTWD 
       370        380        390        400        410        420 
VNEEAKIFIT VNCLSTDFSS QKGVKGLPLM IQIDTYSYNN RSNKPIHRAY CQIKVFCDKG 
       430        440        450        460        470        480 
AERKIRDEER KQNRKKGKGQ ASQTQCNSSS DGKLAAIPLQ KKSDITYFKT MPDLHSQPVL 
       490        500        510        520        530        540 
FIPDVHFANL QRTGQVYYNT DDEREGGSVL VKRMFRPMEE EFGPVPSKQM KEEGTKRVLL 
       550        560        570        580        590        600 
YVRKETDDVF DALMLKSPTV KGLMEAISEK YGLPVEKIAK LYKKSKKGIL VNMDDNIIEH 
       610        620    
YSNEDTFILN MESMVEGFKV TLMEI



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6ISB3-1-unknown MSQESD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6ISB3-17-unknown MPSDPP... 17 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76426

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TLMEI 625 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TLMEI 625 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt72044

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)