TopFIND 4.0

Q6J4K2: Mitochondrial sodium/calcium exchanger protein {ECO:0000305}

General Information

Protein names
- Mitochondrial sodium/calcium exchanger protein {ECO:0000305}
- Na(+)/K(+)/Ca(2+)-exchange protein 6 {ECO:0000250|UniProtKB:Q925Q3}
- Sodium/calcium exchanger protein, mitochondrial {ECO:0000303|PubMed:15060069}
- Sodium/potassium/calcium exchanger 6 {ECO:0000250|UniProtKB:Q925Q3}
- Solute carrier family 24 member 6 {ECO:0000312|HGNC:HGNC:26175}
- Solute carrier family 8 member B1 {ECO:0000312|HGNC:HGNC:26175}
Gene names SLC8B1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6J4K2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGRRLNLRW ALSVLCVLLM AETVSGTRGS STGAHISPQF PASGVNQTPV VDCRKVCGLN 
        70         80         90        100        110        120 
VSDRCDFIRT NPDCHSDGGY LDYLEGIFCH FPPSLLPLAV TLYVSWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TTLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPHTAGLA LGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFFRDIVFYM VAVFLTFLML FRGRVTLAWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVILCTWI YQRQRRGSLF CPMPVTPEIL SDSEEDRVSS NTNSYDYGDE YRPLFFYQET 
       310        320        330        340        350        360 
TAQILVRALN PLDYMKWRRK SAYWKALKVF KLPVEFLLLL TVPVVDPDKD DQNWKRPLNC 
       370        380        390        400        410        420 
LHLVISPLVV VLTLQSGTYG VYEIGGLVPV WVVVVIAGTA LASVTFFATS DSQPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVV FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ ISRSHTEVKL EPDGLLVWVL AGALGLSLVF 
       550        560        570        580    
SLVSVPLQCF QLSRVYGFCL LLFYLNFLVV ALLTEFGVIH LKSM

Isoforms

- Isoform 2 of Sodium/potassium/calcium exchanger 6, mitochondrial - Isoform 2 of Mitochondrial sodium/calcium exchanger protein

Sequence View

        10         20         30         40         50         60 
MAGRRLNLRW ALSVLCVLLM AETVSGTRGS STGAHISPQF PASGVNQTPV VDCRKVCGLN 
        70         80         90        100        110        120 
VSDRCDFIRT NPDCHSDGGY LDYLEGIFCH FPPSLLPLAV TLYVSWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TTLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPHTAGLA LGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFFRDIVFYM VAVFLTFLML FRGRVTLAWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVILCTWI YQRQRRGSLF CPMPVTPEIL SDSEEDRVSS NTNSYDYGDE YRPLFFYQET 
       310        320        330        340        350        360 
TAQILVRALN PLDYMKWRRK SAYWKALKVF KLPVEFLLLL TVPVVDPDKD DQNWKRPLNC 
       370        380        390        400        410        420 
LHLVISPLVV VLTLQSGTYG VYEIGGLVPV WVVVVIAGTA LASVTFFATS DSQPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVV FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ ISRSHTEVKL EPDGLLVWVL AGALGLSLVF 
       550        560        570        580    
SLVSVPLQCF QLSRVYGFCL LLFYLNFLVV ALLTEFGVIH LKSM         10         20         30         40         50         60 
MAGRRLNLRW ALSVLCVLLM AETVSGTRGS STGAHISPQF PASGVNQTPV VDCRKVCGLN 
        70         80         90        100        110        120 
VSDRCDFIRT NPDCHSDGGY LDYLEGIFCH FPPSLLPLAV TLYVSWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TTLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPHTAGLA LGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFFRDIVFYM VAVFLTFLML FRGRVTLAWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVILCTWI YQRQRRGSLF CPMPVTPEIL SDSEEDRVSS NTNSYDYGDE YRPLFFYQET 
       310        320        330        340        350        360 
TAQILVRALN PLDYMKWRRK SAYWKALKVF KLPVEFLLLL TVPVVDPDKD DQNWKRPLNC 
       370        380        390        400        410        420 
LHLVISPLVV VLTLQSGTYG VYEIGGLVPV WVVVVIAGTA LASVTFFATS DSQPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVV FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ ISRSHTEVKL EPDGLLVWVL AGALGLSLVF 
       550        560        570        580    
SLVSVPLQCF QLSRVYGFCL LLFYLNFLVV ALLTEFGVIH LKSM



Filter Information:


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Directness:


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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q6J4K2-1-unknown MAGRRL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82399
    Q6J4K2-27-unknown TRGSST... 27 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q6J4K2-27-unknown TRGSST... 27 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114155

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HLKSM 584 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HLKSM 584 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78017

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)