Q6KAU7: Pleckstrin homology domain-containing family G member 2

General Information

Protein names	- Pleckstrin homology domain-containing family G member 2 - PH domain-containing family G member 2 - Common site lymphoma/leukemia guanine nucleotide exchange factor - Common site lymphoma/leukemia GEF
Gene names	Plekhg2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6KAU7

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEGARGLSL PKPSLRLGCG HQGEVCDCAA VSDTPTAQAA TTMASPRGSG SSTSLSTVGS
        70         80         90        100        110        120
EGDPSPACSA SRPEPLPEPP IRLHLLPVGI QGSVKPSRLE RVAREIVETE RAYVRDLRSI
       130        140        150        160        170        180
VEDYLGPLMD GRALGLNMEQ VGTLFANIED IYEFSSELLE DLEGCSSAGG IAECFVQRSE
       190        200        210        220        230        240
DFDIYTLYCM NYPSSLALLR ELSVSPPATL WLQERQAQLR HSLPLQSFLL KPVQRILKYH
       250        260        270        280        290        300
LLLQELGKHW AEGPDSGGRE MVEEAIVSMT AVAWYINDMK RKQEHAARLQ EVQRRLGGWT
       310        320        330        340        350        360
GPELSAFGEL VLEGTFRGGG GGGPRLRGGE RLLFLFSRML LVAKRRGPEY TYKGHIFCCN
       370        380        390        400        410        420
LSVSETPRDP LGFKVSDLTI PKHRHLFQAK NQEEKRLWIH CLQRLFFENH PASIPAKAKQ
       430        440        450        460        470        480
VLLENSLHCA PKSKHIPEPP TSPLDSPRPR DAPGFTPGRR NPAPSPRLSG SRRGRRQSEP
       490        500        510        520        530        540
AKEAYVIFPQ NDKPQVKHAG SEGELHPSSE LQPVSASGLP EDLEDAGPPT LDPSGTSITE
       550        560        570        580        590        600
EILELLNQRG LRDSGPATHD IPKFPRDSRV PVESEPLPFQ SLPSRESSEE EEEEDLETDE
       610        620        630        640        650        660
REPSPLHVLE GLEGSSAAEI PCIPSLTDIP SEVPSLPEIP EAPCLPCLSD ISGVFEVPCL
       670        680        690        700        710        720
SPTSTVPDIP SLATTPSFPC GSWLPGPLQE AAQPQATRRE LLSGSNPGRL SESPSESREG
       730        740        750        760        770        780
QEDDTEGVSF SAVQREAGTS VQGFPEELEY RSCSEIRSAW QALEQGQLAR PGFPEPLLIL
       790        800        810        820        830        840
EDSDLRGGST SGKTGMPHSE RSASRVRELA RLYSERIQQM QRAETRASTN APRRRPRVLA
       850        860        870        880        890        900
QPQPSPCPPQ EEAEPGALPA FGHVLVCELA FPLNCTQESV PLGPAVLVQA ATPLCIQGDD
       910        920        930        940        950        960
LSGQNLNVSD LSKQGHLSSN SIPPPVPLPG QSNFQNIQVP STSLLPKQEP PDVQVPTAST
       970        980        990       1000       1010       1020
LPDTSQLQSQ VPAATPSAGH RNCVEIQVQS TTSLPGQECQ ADTVALSKQE GHEDSQNPNK
      1030       1040       1050       1060       1070       1080
APGAEQRDVS IDQGLAVVGG RPVSPLPVCT SSPDQQIPAT TPLPLSTDFP DMEGPGALPL
      1090       1100       1110       1120       1130       1140
PTQEGRPDCS IPCNPLPSLS QDVQVPAVIP VSQLQGLTDT RATVPLSSHK QEDAPECLGP
      1150       1160       1170       1180       1190       1200
EPSLTDTPAP RLLSSLGQQN TTDGPVSAAA VPLTEQGCSQ DLQGLITSPV QTTMELPKPR
      1210       1220       1230       1240       1250       1260
GLVSRVATSE SLDLTPPHSP SLSTRQLLGP SAAALSRYLA ASYISQSLAR RQGPGGEGTV
      1270       1280       1290       1300       1310       1320
ASQGHWSSSA PTSRAPSPPP QPQPPAPPAR RLSYATTVSI QVGGGGRLRP AKAQVRLNHP
      1330       1340
ALLAAPHPGA VGPSQGPGGS

Isoforms

- Isoform 2 of Pleckstrin homology domain-containing family G member 2 - Isoform 3 of Pleckstrin homology domain-containing family G member 2

Sequence View

        10         20         30         40         50         60
MPEGARGLSL PKPSLRLGCG HQGEVCDCAA VSDTPTAQAA TTMASPRGSG SSTSLSTVGS
        70         80         90        100        110        120
EGDPSPACSA SRPEPLPEPP IRLHLLPVGI QGSVKPSRLE RVAREIVETE RAYVRDLRSI
       130        140        150        160        170        180
VEDYLGPLMD GRALGLNMEQ VGTLFANIED IYEFSSELLE DLEGCSSAGG IAECFVQRSE
       190        200        210        220        230        240
DFDIYTLYCM NYPSSLALLR ELSVSPPATL WLQERQAQLR HSLPLQSFLL KPVQRILKYH
       250        260        270        280        290        300
LLLQELGKHW AEGPDSGGRE MVEEAIVSMT AVAWYINDMK RKQEHAARLQ EVQRRLGGWT
       310        320        330        340        350        360
GPELSAFGEL VLEGTFRGGG GGGPRLRGGE RLLFLFSRML LVAKRRGPEY TYKGHIFCCN
       370        380        390        400        410        420
LSVSETPRDP LGFKVSDLTI PKHRHLFQAK NQEEKRLWIH CLQRLFFENH PASIPAKAKQ
       430        440        450        460        470        480
VLLENSLHCA PKSKHIPEPP TSPLDSPRPR DAPGFTPGRR NPAPSPRLSG SRRGRRQSEP
       490        500        510        520        530        540
AKEAYVIFPQ NDKPQVKHAG SEGELHPSSE LQPVSASGLP EDLEDAGPPT LDPSGTSITE
       550        560        570        580        590        600
EILELLNQRG LRDSGPATHD IPKFPRDSRV PVESEPLPFQ SLPSRESSEE EEEEDLETDE
       610        620        630        640        650        660
REPSPLHVLE GLEGSSAAEI PCIPSLTDIP SEVPSLPEIP EAPCLPCLSD ISGVFEVPCL
       670        680        690        700        710        720
SPTSTVPDIP SLATTPSFPC GSWLPGPLQE AAQPQATRRE LLSGSNPGRL SESPSESREG
       730        740        750        760        770        780
QEDDTEGVSF SAVQREAGTS VQGFPEELEY RSCSEIRSAW QALEQGQLAR PGFPEPLLIL
       790        800        810        820        830        840
EDSDLRGGST SGKTGMPHSE RSASRVRELA RLYSERIQQM QRAETRASTN APRRRPRVLA
       850        860        870        880        890        900
QPQPSPCPPQ EEAEPGALPA FGHVLVCELA FPLNCTQESV PLGPAVLVQA ATPLCIQGDD
       910        920        930        940        950        960
LSGQNLNVSD LSKQGHLSSN SIPPPVPLPG QSNFQNIQVP STSLLPKQEP PDVQVPTAST
       970        980        990       1000       1010       1020
LPDTSQLQSQ VPAATPSAGH RNCVEIQVQS TTSLPGQECQ ADTVALSKQE GHEDSQNPNK
      1030       1040       1050       1060       1070       1080
APGAEQRDVS IDQGLAVVGG RPVSPLPVCT SSPDQQIPAT TPLPLSTDFP DMEGPGALPL
      1090       1100       1110       1120       1130       1140
PTQEGRPDCS IPCNPLPSLS QDVQVPAVIP VSQLQGLTDT RATVPLSSHK QEDAPECLGP
      1150       1160       1170       1180       1190       1200
EPSLTDTPAP RLLSSLGQQN TTDGPVSAAA VPLTEQGCSQ DLQGLITSPV QTTMELPKPR
      1210       1220       1230       1240       1250       1260
GLVSRVATSE SLDLTPPHSP SLSTRQLLGP SAAALSRYLA ASYISQSLAR RQGPGGEGTV
      1270       1280       1290       1300       1310       1320
ASQGHWSSSA PTSRAPSPPP QPQPPAPPAR RLSYATTVSI QVGGGGRLRP AKAQVRLNHP
      1330       1340
ALLAAPHPGA VGPSQGPGGS         10         20         30         40         50         60
MPEGARGLSL PKPSLRLGCG HQGEVCDCAA VSDTPTAQAA TTMASPRGSG SSTSLSTVGS
        70         80         90        100        110        120
EGDPSPACSA SRPEPLPEPP IRLHLLPVGI QGSVKPSRLE RVAREIVETE RAYVRDLRSI
       130        140        150        160        170        180
VEDYLGPLMD GRALGLNMEQ VGTLFANIED IYEFSSELLE DLEGCSSAGG IAECFVQRSE
       190        200        210        220        230        240
DFDIYTLYCM NYPSSLALLR ELSVSPPATL WLQERQAQLR HSLPLQSFLL KPVQRILKYH
       250        260        270        280        290        300
LLLQELGKHW AEGPDSGGRE MVEEAIVSMT AVAWYINDMK RKQEHAARLQ EVQRRLGGWT
       310        320        330        340        350        360
GPELSAFGEL VLEGTFRGGG GGGPRLRGGE RLLFLFSRML LVAKRRGPEY TYKGHIFCCN
       370        380        390        400        410        420
LSVSETPRDP LGFKVSDLTI PKHRHLFQAK NQEEKRLWIH CLQRLFFENH PASIPAKAKQ
       430        440        450        460        470        480
VLLENSLHCA PKSKHIPEPP TSPLDSPRPR DAPGFTPGRR NPAPSPRLSG SRRGRRQSEP
       490        500        510        520        530        540
AKEAYVIFPQ NDKPQVKHAG SEGELHPSSE LQPVSASGLP EDLEDAGPPT LDPSGTSITE
       550        560        570        580        590        600
EILELLNQRG LRDSGPATHD IPKFPRDSRV PVESEPLPFQ SLPSRESSEE EEEEDLETDE
       610        620        630        640        650        660
REPSPLHVLE GLEGSSAAEI PCIPSLTDIP SEVPSLPEIP EAPCLPCLSD ISGVFEVPCL
       670        680        690        700        710        720
SPTSTVPDIP SLATTPSFPC GSWLPGPLQE AAQPQATRRE LLSGSNPGRL SESPSESREG
       730        740        750        760        770        780
QEDDTEGVSF SAVQREAGTS VQGFPEELEY RSCSEIRSAW QALEQGQLAR PGFPEPLLIL
       790        800        810        820        830        840
EDSDLRGGST SGKTGMPHSE RSASRVRELA RLYSERIQQM QRAETRASTN APRRRPRVLA
       850        860        870        880        890        900
QPQPSPCPPQ EEAEPGALPA FGHVLVCELA FPLNCTQESV PLGPAVLVQA ATPLCIQGDD
       910        920        930        940        950        960
LSGQNLNVSD LSKQGHLSSN SIPPPVPLPG QSNFQNIQVP STSLLPKQEP PDVQVPTAST
       970        980        990       1000       1010       1020
LPDTSQLQSQ VPAATPSAGH RNCVEIQVQS TTSLPGQECQ ADTVALSKQE GHEDSQNPNK
      1030       1040       1050       1060       1070       1080
APGAEQRDVS IDQGLAVVGG RPVSPLPVCT SSPDQQIPAT TPLPLSTDFP DMEGPGALPL
      1090       1100       1110       1120       1130       1140
PTQEGRPDCS IPCNPLPSLS QDVQVPAVIP VSQLQGLTDT RATVPLSSHK QEDAPECLGP
      1150       1160       1170       1180       1190       1200
EPSLTDTPAP RLLSSLGQQN TTDGPVSAAA VPLTEQGCSQ DLQGLITSPV QTTMELPKPR
      1210       1220       1230       1240       1250       1260
GLVSRVATSE SLDLTPPHSP SLSTRQLLGP SAAALSRYLA ASYISQSLAR RQGPGGEGTV
      1270       1280       1290       1300       1310       1320
ASQGHWSSSA PTSRAPSPPP QPQPPAPPAR RLSYATTVSI QVGGGGRLRP AKAQVRLNHP
      1330       1340
ALLAAPHPGA VGPSQGPGGS

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6KAU7-1-unknown	MPEGAR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6KAU7-1-unknown	MPEGAR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85391
Q6KAU7-43-unknown	MASPRG...	43	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85390
Q6KAU7-43-unknown	MASPRG...	43	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt103940

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VGSEGD	62	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122050
...VGSEGD	62	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt118681
...RELSVS	204	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118217
...RELSVS	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt118677
...RELSVS	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt118678
...VSDLSK	912	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115651
...VSDLSK	912	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt118674
...VSDLSK	912	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt118675
...GPGGS	1340	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GPGGS	1340	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81008
...GPGGS	1340	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81009

TopFIND

Q6KAU7: Pleckstrin homology domain-containing family G member 2

General Information

2

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates